Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ron Kerkhoven"'
Autor:
Xin Lei, Indu Khatri, Tom de Wit, Iris de Rink, Marja Nieuwland, Ron Kerkhoven, Hans van Eenennaam, Chong Sun, Abhishek D. Garg, Jannie Borst, Yanling Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
The presence of classical type 1 dendritic cells (cDC1) positively influences prognosis in cancer, but their intricate networking with the various T cell types found in the tumour microenvironment is not fully appreciated. Here the authors show that
Externí odkaz:
https://doaj.org/article/c8c7c60050dc41968a22f225d73ae370
Autor:
Julia M. Houthuijzen, Roebi de Bruijn, Eline van der Burg, Anne Paulien Drenth, Ellen Wientjens, Tamara Filipovic, Esme Bullock, Chiara S. Brambillasca, Emilia M. Pulver, Marja Nieuwland, Iris de Rink, Frank van Diepen, Sjoerd Klarenbeek, Ron Kerkhoven, Valerie G. Brunton, Colinda L.G.J. Scheele, Mirjam C. Boelens, Jos Jonkers
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
The origin of cancer-associated fibroblasts (CAFs) in cancer remains to be identified. Here, single-cell transcriptomics, in vivo and in vitro studies suggest that CD26+ and CD26- normal fibroblasts transform into distinct CAF subpopulations in mouse
Externí odkaz:
https://doaj.org/article/98fa8f8030b34a05844572c6f0069230
Autor:
Rosa A. Krimpenfort, Felix M. Behr, Marja Nieuwland, Iris de Rink, Ron Kerkhoven, Marieke von Lindern, Micha Nethe
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1706 (2022)
E-cadherin is a key regulator of epithelial cell–cell adhesion, the loss of which accelerates tumor growth and invasion. E-cadherin is also expressed in hematopoietic cells as well as epithelia. The function of hematopoietic E-cadherin is, however,
Externí odkaz:
https://doaj.org/article/a914931423c94e2dab2c0c3a66e2890f
Autor:
Alberto Gil-Jimenez, Jeroen van Dorp, Alberto Contreras-Sanz, Kristan van der Vos, Daniel J. Vis, Linde Braaf, Annegien Broeks, Ron Kerkhoven, Kim E.M. van Kessel, María José Ribal, Antonio Alcaraz, Lodewyk F.A. Wessels, Roland Seiler, Jonathan L. Wright, Lourdes Mengual, Joost Boormans, Bas W.G. van Rhijn, Peter C. Black, Michiel S. van der Heijden
Publikováno v:
European Urology, 83(4), 313-317. Elsevier
Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy is recommended for patients with muscle-invasive bladder cancer (MIBC). It has been shown that somatic deleterious mutations in ERCC2, gain-of-function mutations in ERBB2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea18b92415cba71106d1ad203bbbff7
https://doi.org/10.1016/j.eururo.2022.07.023
https://doi.org/10.1016/j.eururo.2022.07.023
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Supplementary Figure 1 and Tables 1-8. Supplementary figure 1. Heatmap of common response, 2 and 6 hours after irradiation. Heatmap of the common response to 4 Gy irradiation in all 32 cell lines, adapted from the BRB-array tools time course plug-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c75d76e59327c9a6632145004d999f
https://doi.org/10.1158/1078-0432.22460798.v1
https://doi.org/10.1158/1078-0432.22460798.v1
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Supplementary Information. This file contains a text file with the interactions between miRs and mRNAs used for the analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86459a1a7fd7e7b93db1cf1973b48578
https://doi.org/10.1158/1078-0432.22460795
https://doi.org/10.1158/1078-0432.22460795
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Purpose: Predominant causes of head and neck cancer recurrence after radiotherapy are rapid repopulation, hypoxia, fraction of cancer stem cells, and intrinsic radioresistance. Currently, intrinsic radioresistance can only be assessed by ex vivo colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3921aee5c179bb9b506e07f368a84821
https://doi.org/10.1158/1078-0432.c.6524594.v1
https://doi.org/10.1158/1078-0432.c.6524594.v1
Autor:
Wilbert Zwart, Els M.J.J. Berns, Sabine C. Linn, Lodewyk Wessels, John A. Foekens, Xanthippi Alexi, Luc Dirix, Steven van Laere, Arno Velds, Marjolein Droog, Ron Kerkhoven, Iris Simon, Esther A. Reijm, Theo Knijnenburg, Maurice P.H.M. Jansen
PDF file - 56K, Supplementary Table S3 Read count, filtering and number of peaks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761622b87aadbfe89a440236809be051
https://doi.org/10.1158/0008-5472.22396988.v1
https://doi.org/10.1158/0008-5472.22396988.v1
Autor:
Wilbert Zwart, Els M.J.J. Berns, Sabine C. Linn, Lodewyk Wessels, John A. Foekens, Xanthippi Alexi, Luc Dirix, Steven van Laere, Arno Velds, Marjolein Droog, Ron Kerkhoven, Iris Simon, Esther A. Reijm, Theo Knijnenburg, Maurice P.H.M. Jansen
PDF file - 101K, Supplementary Figure S5 Venn diagram, depicting the level of overlap of genes between 'proximity' and 'functionality' genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293510ffca54cff9d418f9216073fa4d
https://doi.org/10.1158/0008-5472.22397009.v1
https://doi.org/10.1158/0008-5472.22397009.v1
Autor:
Wilbert Zwart, Els M.J.J. Berns, Sabine C. Linn, Lodewyk Wessels, John A. Foekens, Xanthippi Alexi, Luc Dirix, Steven van Laere, Arno Velds, Marjolein Droog, Ron Kerkhoven, Iris Simon, Esther A. Reijm, Theo Knijnenburg, Maurice P.H.M. Jansen
PDF file - 46K, Supplementary Table S2 Clinicopathological characteristics of the aromatase inhibitor cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7962f7cfc1899d16535c70a46137cf19
https://doi.org/10.1158/0008-5472.22396994.v1
https://doi.org/10.1158/0008-5472.22396994.v1