Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Ron Kasher"'
1
Miniaturized proteins: the backbone cyclic proteinomimetic approach 1 1Edited by A. R. Fersht
Autor: Yaniv Barda, Ron Kasher, Chaim Gilon, Deena A. Oren
Publikováno v: Journal of Molecular Biology. 292:421-429
The field of proteinomimetics utilizes peptide-based molecules to mimic native protein functions. We describe a novel general method for mimicking proteins by small cyclic peptides for the purpose of drug design, and demonstrate its applicability on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00aeb81463a5d4207427ef4f90fb4094
https://doi.org/10.1006/jmbi.1999.3053
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2
Building units for N-backbone cyclic peptides. Part 4.1 Synthesis of protected Nα-functionalized alkyl amino acids by reductive alkylation of natural amino acids
Autor: Ron Kasher, Chaim Gilon, Gal Bitan, Evgenia V. Gluhov, Dan Muller
Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :1501-1510
A new method for the synthesis of protected Nα-(ω-Y-alkyl) amino acids (Y is a thio, amino or carboxy group) and related compounds by reductive alkylation of natural amino acids is reported. These new amino acids serve as building units for the syn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::781cebfca8a74add8126cf5ea3d5f14a
https://doi.org/10.1039/a608389g
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3
Electron-Transfer Communication in Glutathione Reductase Assemblies: Electrocatalytic, Photocatalytic, and Catalytic Systems for the Reduction of Oxidized Glutathione
Autor: Ron Kasher, Eugenii Katz, Itamar Willner, Noa Lapidot, Azalia Riklin, Eran Zahavy
Publikováno v: Journal of the American Chemical Society. 116:1428-1441
Glutathione reductase, GR, is electrically communicated with its environment in electrochemical, photochemical, and chemical assemblies. Electron-transfer communication between the protein redox site and its surroundings is achieved either by covalen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d883cc6a85354c804c49fdbb53b587a2
https://doi.org/10.1021/ja00083a031
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5
Synthesis of a bicyclic BPTI mimetic containing 4-thioproline replacing Cys38
Autor: Christeen Halloun, Ron Kasher, Chaim Gilon, Gal Bitan
Publikováno v: Letters in Peptide Science. 5:101-103
The synthesis of a backbone bicyclic nonapeptide that mimics the binding site of bovine pancreatic trypsin inhibitor (BPTI) is described. The BPTI mimetic, which contains cis-thioproline replacing Cys38 of the protein, inhibits trypsin with a Ki of 7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd0bfff8e9dc3e7d9184906de705aa72
https://doi.org/10.1007/bf02443447
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6
Electron-transfer communication between redox-functionalized polymers and the active center of the enzyme glutathione reductase
Autor: Noa Lapidot, Ron Kasher, Eran Zahavy, Itamar Willner
Publikováno v: Journal of the American Chemical Society. 114:10963-10965
cyclohexanones-even by a relatively bulky reducing agent such as an alkoxysiliconate ion.Is The relatively greater yield of cis product from 2 compared to 1 is believed to be due, in part, to axial reduction of the small amount of the higher energy s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1aafc46c72d413a3fe1d12e5a5519164
https://doi.org/10.1021/ja00053a044
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