Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ron K. Wolff"'
Publikováno v:
Inhalation Toxicology. 25:219-232
Biopharmaceuticals are complex molecules often manufactured from living systems and their specificity and novelty holds great promise for the treatment of chronic diseases for which there are currently no cures. The inhalation route of biopharmaceuti
Autor:
Lee M. Nagao, Roger O McClellan, Wmark Vogel, David Jacobson-Kram, Timothy McGovern, Ron K. Wolff, Daniel L. Norwood, Douglas J. Ball, James Blanchard
Publikováno v:
Toxicological Sciences. 97:226-236
Safety thresholds for chemical impurities and leachables in consumer products such as foods and drugs have helped to ensure public health while establishing scientifically sound limits for identification and risk assessment of these compounds. The Pr
Autor:
Lea Ann Dailey, Colin J. Hardy, Per Gerde, Ben Forbes, Graham Somers, Douglas Ferguson, Tim McGovern, Gary R. Pitcairn, Ron K. Wolff, David G. Hassall, Ruth Lock, Rhys M. Jones, Janet Maas, Bahman Asgharian, Lena Gustavsson, Mark Gumbleton
Publikováno v:
Advanced drug delivery reviews. 63(1-2)
Dosimetry, safety and the efficacy of drugs in the lungs are critical factors in the development of inhaled medicines. This article considers the challenges in each of these areas with reference to current industry practices for developing inhaled pr
Autor:
McElroy, Mary C.1 (AUTHOR) Mary.Mcelroy@crl.com, Kirton, Chris2 (AUTHOR), Gliddon, Dan3 (AUTHOR), Wolff, Ron K.4 (AUTHOR)
Publikováno v:
Inhalation Toxicology. Mar2013, Vol. 25 Issue 4, p219-232. 14p.
Autor:
Philip Chi Lip Kwok, Hak-Kim Chan
The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generall