Výsledky vyhledávání - "Ron J. Jankowski"

A double-blind, randomized, placebo-controlled clinical trial evaluating the safety and efficacy of autologous muscle derived cells in female subjects with stress urinary incontinence

Autor: Christopher Carlson, Min Chen, Scott Snyder, Michael B. Chancellor, Kevin Carlson, Le Mai Tu, David M. Quinlan, Magali Robert, Lesley K. Carr, Ron J. Jankowski, Roger R. Dmochowski, Andreas Eisenhardt, Ryan Pruchnic, Melissa R. Kaufman

Publikováno v: International Urology and Nephrology. 50:2153-2165

The purpose of the study was to assess safety and efficacy of autologous muscle derived cells for urinary sphincter repair (AMDC-USR) in female subjects with predominant stress urinary incontinence. A randomized, double-blind, multicenter trial exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a157ead5e56fce972beb567c7386ec0e
https://doi.org/10.1007/s11255-018-2005-8

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Human Skeletal Muscle Cells With a Slow Adhesion Rate After Isolation and an Enhanced Stress Resistance Improve Function of Ischemic Hearts

Autor: Lauren Drowley, Johnny Huard, Bradley B. Keller, Masaho Okada, William C.W. Chen, Kimimasa Tobita, Thomas Payne, Ron J. Jankowski, Sarah A Beckman, Nobuo Momoi

Publikováno v: Molecular Therapy. 20(1):138-145

Identification of cells that are endowed with maximum potency could be critical for the clinical success of cell-based therapies. We investigated whether cells with an enhanced efficacy for cardiac cell therapy could be enriched from adult human skel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a3031fa882ca7ce637ea9f4987ab8c

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Endoscopic injection of skeletal muscle–derived cells augments gut smooth muscle sphincter function: implications for a novel therapeutic approach

Autor: Pankaj J. Pasricha, Ijaz Ahmed, Maria-Adelaide Micci, Ron J. Jankowski

Publikováno v: Gastrointestinal Endoscopy. 70:1231-1237

Introduction Sphincter function is a common problem in gastroenterology and leads to disorders such as GERD and fecal incontinence. Objective We hypothesized that transplantation of skeletal muscle–derived cells (MDCs) into GI sphincters may improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::690885d447d003d2ace2627073234d13
https://doi.org/10.1016/j.gie.2009.05.014

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Regenerative Therapy for Stress Urinary Incontinence

Autor: David Wagner, Michael B. Chancellor, Ryan Pruchnic, Ron J. Jankowski

Publikováno v: Tzu Chi Medical Journal. 20(3):169-176

In anatomical and functional studies of the human and animal urethra, the middle urethral contained rhabdosphincter is critical for maintaining continence. Transplanted muscle and/or stem cells may have the ability to undergo self-renewal and multipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb44da880fa6fa2ac4fe3c5b93c55a37

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State of the art of where we are at using stem cells for stress urinary incontinence

Autor: Naoki Yoshimura, Ryan Pruchnic, Akira Furuta, Michael B. Chancellor, Masashi Honda, Ron J. Jankowski

Publikováno v: Neurourology and Urodynamics. 26:966-971

Aims This review aims to discuss: 1) the neurophysiology, highlighting the importance of the middle urethra, and treatment of stress urinary incontinence (SUI); 2) current injectable cell sources for minimally-invasive treatment; and 3) the potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2484b91026dca3e2547d99847c9ce063
https://doi.org/10.1002/nau.20448

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Periurethral cellular injection: Comparison of muscle-derived progenitor cells and fibroblasts with regard to efficacy and tissue contractility in an animal model of stress urinary incontinence

Autor: Yong Tae Kim, Johnny Huard, Ryan Pruchnic, Fernando De Miguel, Ron J. Jankowski, Irma Usiene, Michael B. Chancellor, Dong Deuk Kwon

Publikováno v: Urology. 68:449-454

Objectives To compare muscle-derived cells (MDCs) and fibroblasts with regard to their potential for restoration of urethral function on injection in a previously established animal model of stress urinary incontinence. Methods The animals were divid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84839bcfd66cc323e67c06696a704c78
https://doi.org/10.1016/j.urology.2006.03.040

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