Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ron Drengler"'
Autor:
Michael J. Wick, Alexander W. Miller, Monica Farley, Amita Patnaik, Kyriakos P. Papadopoulos, Teresa L. Vaught, Drew W. Rasco, Ron Drengler, Anthony W. Tolcher, Lizette Gamez
Publikováno v:
Molecular Cancer Therapeutics. 12:A13-A13
Background: A majority of metastatic melanomas are driven by BRAF and NRAS mutations in the MAP/ERK kinase pathway. Recently approved therapies targeting B-Raf and Erk kinases have improved patient outcome; however, anticancer effects of these agents
Autor:
Lizette Gamez, Anthony W. Tolcher, Lon Smith, Michael J. Wick, Kyriakos P. Papadopoulos, Amita Patnaik, Drew W. Rasco, Teresa L. Vaught, Ron Drengler, Armando Diaz
Publikováno v:
Molecular Cancer Therapeutics. 12:A107-A107
Background: Regorafenib is a multi-tyrosine kinase recently approved for unresectable and drug refractory gastrointestinal stromal tumors (GIST) and treatment-refractory colorectal cancers regardless of Ras status. While a subset of colorectal cancer