Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ron Boch"'
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Canadian academic and industry stakeholders are concerned about the inclusion of “virus-like particles or sub-viral particles” in the definition of New Substances Notification Regulations for Organisms (NSNR(O)) which impacts clinical cell and ge
Externí odkaz:
https://doaj.org/article/bc75517d72444008bdcecc980e5bc200
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :146-155
A series of β,β-dihydroxychlorins derived from meso-tetraphenylporphyrins (TPPs) have been synthesized. Their in vitro cytotoxicity has been measured and compared to BPDMA (verteporfin). Under the assay conditions BPDMA had an LD 50 (lethal dose to
Publikováno v:
Canadian Journal of Chemistry. 79:1068-1074
The photophysical properties of a ring B benzoporphyrin derivative 1,3-diene dimethylester were investigated in solution (waterDMSO mixtures). At low proportions of water in DMSO, the diester obeys Beer's law at all pH values and ionic strengths in
Autor:
Alice J. Canaan, John Robert North, Ethan Sternberg, Anna M. Richter, Angela Cho, Claire Smits, Lina Hong, Ron Boch, David Dolphin, Ashok K. Jain
Publikováno v:
Photochemistry and photobiology. 82(1)
A newly synthesized diethylene glycol functionalized chlorin-type photosensitizer, lemuteporfin, was characterized for use in photodynamic therapy (PDT) in a panel of in vitro and in vivo test systems. The photosensitizer was highly potent, killing c
Autor:
Theresa M. Allen, Janny X. Zhang, Anthony S. K. Vancouver Boey, Ron Boch, Christian B. Hansen
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 86(2-3)
In this paper, we describe the development of micellar formulations for increasing the solubility of lipophilic benzoporphyrins. Using a simple procedure that is readily adaptable for large-scale manufacturing, both A-ring (1) and B-ring isomers (2)
Autor:
Alon Peled, Ofer Sarig, Liat Samuelov, Marta Bertolini, Limor Ziv, Daphna Weissglas-Volkov, Marina Eskin-Schwartz, Christopher A Adase, Natalia Malchin, Ron Bochner, Gilad Fainberg, Ilan Goldberg, Koji Sugawara, Avital Baniel, Daisuke Tsuruta, Chen Luxenburg, Noam Adir, Olivier Duverger, Maria Morasso, Stavit Shalev, Richard L Gallo, Noam Shomron, Ralf Paus, Eli Sprecher
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006369 (2016)
Despite recent advances in our understanding of the pathogenesis of ectodermal dysplasias (EDs), the molecular basis of many of these disorders remains unknown. In the present study, we aimed at elucidating the genetic basis of a new form of ED featu
Externí odkaz:
https://doaj.org/article/2a310f48642d4138a48fbddd5896a7f3
Autor:
Dan Vodo, Ofer Sarig, Shamir Geller, Edna Ben-Asher, Tsviya Olender, Ron Bochner, Ilan Goldberg, Judith Nosgorodsky, Anna Alkelai, Pavel Tatarskyy, Alon Peled, Sharon Baum, Aviv Barzilai, Saleh M Ibrahim, Detlef Zillikens, Doron Lancet, Eli Sprecher
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006008 (2016)
Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous blistering disease caused by disruption of intercellular adhesion due to auto-antibodies directed against epithelial components. Treatment is limited to immunosuppressive agents,
Externí odkaz:
https://doaj.org/article/a12a4bbe1ad744ff8c325b9792779ab8
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