Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ron A. Hoebe"'
Autor:
Anna C. Nuijens, Arlene L. Oei, Lisa Koster, Ron A. Hoebe, Nicolaas A.P. Franken, Coen R.N. Rasch, Lukas J.A. Stalpers
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background A predictive assay for late radiation toxicity would allow more personalized treatment planning, reducing the burden of toxicity for the more sensitive minority, and improving the therapeutic index for the majority. In a previous
Externí odkaz:
https://doaj.org/article/22edc391216a45a5a7f4fc0566347cc8
Autor:
Selami Baglamis, Vivek M. Sheraton, Debora Meijer, Haibin Qian, Ron A. Hoebe, Kristiaan J Lenos, Max A. Betjes, Sander Tans, Jeroen van Zon, Louis Vermeulen, Przemek M. Krawczyk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Clonal growth and competition underlie processes of key relevance in etiology, progression and therapy response across all cancers. Here, we demonstrate a novel experimental approach, based on multi-color, fluorescent tagging of cell nuclei,
Externí odkaz:
https://doaj.org/article/05a85a4d65f946e1b17ffb699bf1566f
Autor:
Haibin Qian, Ron A. Hoebe, Michel R. Faas, Marc Jan van Goethem, Emiel R. van der Graaf, Christoph Meyer, Harry Kiewiet, Sytze Brandenburg, Przemek M. Krawczyk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cellular responses to DNA double-strand breaks (DSBs) not only promote genomic integrity in healthy tissues, but also largely determine the efficacy of many DNA-damaging cancer treatments, including X-ray and particle therapies. A growing bo
Externí odkaz:
https://doaj.org/article/f53b3751d3154ed185a148a298d26f11
Autor:
I. Michel Antolovic, Samuel Burri, Ron A. Hoebe, Yuki Maruyama, Claudio Bruschini, Edoardo Charbon
Publikováno v:
Sensors, Vol 16, Iss 7, p 1005 (2016)
The paper presents a camera comprising 512 × 128 pixels capable of single-photon detection and gating with a maximum frame rate of 156 kfps. The photon capture is performed through a gated single-photon avalanche diode that generates a digital pulse
Externí odkaz:
https://doaj.org/article/2188aea3bc6e4699937c0969aaf12c74
Autor:
Gerarda H. Khan, Floor Veltkamp, Mirte Scheper, Ron A. Hoebe, Nike Claessen, Loes Butter, Antonia H.M. Bouts, Sandrine Florquin, Jeroen E.J. Guikema
Levamisole (LMS) is a small molecule used in the treatment of idiopathic nephrotic syndrome (INS). The pathogenesis of INS remains unknown, but most evidence points towards an immunological basis of the disease. Recently, LMS has been shown to increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15de4a79dbdaf4e8a2cdbd44ae892ff
https://doi.org/10.1101/2023.05.08.539819
https://doi.org/10.1101/2023.05.08.539819
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
D-2HG inhibits IDH-mediated NADPH production capacity, but not G6PD-mediated NADPH production capacity or IDH-mediated NADH production capacity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c00fef62eafc6548de46176770adc97
https://doi.org/10.1158/0008-5472.22412280.v1
https://doi.org/10.1158/0008-5472.22412280.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
SPSS output statistics for comparisons between survival curves from colony-formation assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d1222c3980f828fe4ee1f14a765f79
https://doi.org/10.1158/0008-5472.22412268.v1
https://doi.org/10.1158/0008-5472.22412268.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
Isocitrate dehydrogenase 1 (IDH1) is mutated in various types of human cancer to IDH1R132H, a structural alteration that leads to catalysis of α-ketoglutarate to the oncometabolite D-2-hydroxyglutarate. In this study, we present evidence that small-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c1fa1f1ef7af279dc9e5e587d4809e
https://doi.org/10.1158/0008-5472.c.6508407.v1
https://doi.org/10.1158/0008-5472.c.6508407.v1
Autor:
Enzo M. Scutigliani, Yongxin Liang, Marloes IJff, Hans Rodermond, Xionge Mei, Miriam P. Korver, Vaneesha S. Orie, Ron A. Hoebe, Daisy I. Picavet, Arlene Oei, Roland Kanaar, Przemek M. Krawczyk
Publikováno v:
Cancers, 14(21):5250. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers; Volume 14; Issue 21; Pages: 5250
Cancers; Volume 14; Issue 21; Pages: 5250
Hyperthermia is being used as a radio- and chemotherapy sensitizer for a growing range of tumor subtypes in the clinic. Its potential is limited, however, by the ability of cancer cells to activate a protective mechanism known as the heat stress resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d50a4880dffeeb81fc955ae73e2fa6
https://pure.amc.nl/en/publications/evaluation-of-the-heat-shock-protein-90-inhibitor-ganetespib-as-a-sensitizer-to-hyperthermiabased-cancer-treatments(bbb07e88-3cd7-4c56-859d-f5edddd25274).html
https://pure.amc.nl/en/publications/evaluation-of-the-heat-shock-protein-90-inhibitor-ganetespib-as-a-sensitizer-to-hyperthermiabased-cancer-treatments(bbb07e88-3cd7-4c56-859d-f5edddd25274).html
Autor:
Karlijne W. Geijtenbeek, Jolien Janzen, Aleksandra E. Bury, Alicia Sanz-Sanz, Ron A. Hoebe, Marie K. Bondulich, Gillian P. Bates, Eric A. J. Reits, Sabine Schipper-Krom
Publikováno v:
PLoS ONE, 17(12 December):e0278130. Public Library of Science
Huntington’s disease is an autosomal dominant heritable disorder caused by an expanded CAG trinucleotide repeat at the N-terminus of the Huntingtin (HTT) gene. Lowering the levels of soluble mutant HTT protein prior to aggregation through increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f2f55d79f4bfca07123fb2074942d8
https://pubmed.ncbi.nlm.nih.gov/36574405
https://pubmed.ncbi.nlm.nih.gov/36574405