Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ron A. A. Math"'
Autor:
Michael E. Cloesmeijer, Erik Sjögren, Sjoerd F. Koopman, Peter. J. Lenting, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1630-1640 (2024)
Abstract Patients with severe and sometimes moderate hemophilia B are prophylactically treated with factor IX concentrates to prevent bleeding. For some time now, various extended terminal half‐life (EHL) recombinant factor IX concentrates are avai
Externí odkaz:
https://doaj.org/article/5f163a5353a04a9587192c9f9d3e1653
Autor:
Amadou Samb, Thomas H. Dierikx, Yuma A. Bijleveld, Timo R. de Haan, Caspar J. Hodiamont, Elisabeth van Leeuwen, Anton H. L. C. van Kaam, Ron A. A. Mathôt, Douwe H. Visser
Publikováno v:
Maternal Health, Neonatology and Perinatology, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Background and method Dutch obstetrics guideline suggest an initial maternal benzylpenicillin dose of 2,000,000 IU followed by 1,000,000 IU every 4 h for group-B-streptococci (GBS) prophylaxis. The objective of this study was to evaluate whe
Externí odkaz:
https://doaj.org/article/f3c37e13c8184d7e9ecbf6410c3e2e96
Autor:
Laura H. Bukkems, Siv Jönsson, Marjon H. Cnossen, Mats O. Karlsson, Ron A. A. Mathôt, the OPTI‐CLOT studies and the SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 706-718 (2023)
Abstract Publications on the exposure‐effect relationships of factor concentrates for hemophilia treatment are limited, whereas such analyses give insight on treatment efficacy. Our objective was to examine the relationship between the dose, factor
Externí odkaz:
https://doaj.org/article/7eec7fdf7ae047a5bdab05ee3fb2e3b5
Autor:
Luca F. Roggeveen, Tingjie Guo, Lucas M. Fleuren, Ronald Driessen, Patrick Thoral, Reinier M. van Hest, Ron A. A. Mathot, Eleonora L. Swart, Harm-Jan de Grooth, Bas van den Bogaard, Armand R. J. Girbes, Rob J. Bosman, Paul W. G. Elbers
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)
Abstract Background Adequate antibiotic dosing may improve outcomes in critically ill patients but is challenging due to altered and variable pharmacokinetics. To address this challenge, AutoKinetics was developed, a decision support system for bedsi
Externí odkaz:
https://doaj.org/article/6a01424511e0433f9b3a6d071324f5c2
Autor:
Alexander Janssen, Mark Hoogendoorn, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT Study Group and SYMPHONY Consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 8, Pp 1100-1110 (2022)
Abstract In population pharmacokinetic (PK) models, interindividual variability is explained by implementation of covariates in the model. The widely used forward stepwise selection method is sensitive to bias, which may lead to an incorrect inclusio
Externí odkaz:
https://doaj.org/article/0ab8e6d545d7478e9376b677b1290db2
Autor:
Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 7, Pp 934-945 (2022)
Abstract Nonlinear mixed effect (NLME) models are the gold standard for the analysis of patient response following drug exposure. However, these types of models are complex and time‐consuming to develop. There is great interest in the adoption of m
Externí odkaz:
https://doaj.org/article/9c0772ba25f9456fb3e8391b85d47457
Autor:
Thomas Kerbusch, Hans M. M. B. Otten, Hendrikus J. M. Van Kan, Jos H. Beijnen, Ron A. A. Math, Jan H.M. Schellens, Eelco W. Meesters
Publikováno v:
Pharmacology & Toxicology. 90:243-245
We report a case of a 39-year-old male with bipolar affective disorder who was admitted to hospital with an intentional acute lithium intoxication resulting in renal insufficiency. The patient had previously been treated with lithium, risperidone, fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7328378e6fadf5ca7a447abb8d96af78
https://doi.org/10.1034/j.1600-0773.2002.900503.x
https://doi.org/10.1034/j.1600-0773.2002.900503.x
Autor:
Youssef Chahid, Nienke M. G. Rorije, Soufian el Boujoufi, Ron A. A. Mathôt, Liffert Vogt, Hein J. Verberne
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Background Increased vascular permeability is an early sign of vascular damage and can be measured with the transcapillary escape rate of albumin (TERalb). Although TERalb has a multi-exponential kinetic model, most published TERalb data are
Externí odkaz:
https://doaj.org/article/8ef6f9eeefcc429987c1d50eb22c87ef
Autor:
Anne Steins, Remy Klaassen, Igor Jacobs, Matthias C. Schabel, Monique G. J. T. B. vanLier, Eva A. Ebbing, Stefanie J. Hectors, Sander W. Tas, Chrissta X. Maracle, Cornelis J. A. Punt, Maria Siebes, Jacques J. G. H. M. Bergman, Jan Paul Medema, Johanna W. Wilmink, Ron A. A. Mathot, Gustav J. Strijkers, Maarten F. Bijlsma, Hanneke W. M. vanLaarhoven
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 704-720 (2020)
Anti‐angiogenic agents combined with chemotherapy is an important strategy for the treatment of solid tumors. However, survival benefit is limited, urging the improvement of combination therapies. We aimed to clarify the effects of vascular endothe
Externí odkaz:
https://doaj.org/article/4fc054b713b34feebcdc0f4ca8a8d073
Autor:
Saskia E. Zieck, Suzanne L. de Vroom, Frouke Ph. Mulder, Gitte van Twillert, Ron A. A. Mathôt, Suzanne E. Geerlings, Reinier M. van Hest
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 469 (2023)
No prospective evidence exists on the pharmacokinetic/pharmacodynamic (PK/PD) target attainment of ceftazidime in adult patients on general wards. We aimed to investigate whether the PK/PD target of ceftazidime (50% T > MIC) is attained in adult pati
Externí odkaz:
https://doaj.org/article/d6cf004ab4a246269165059832481ab1