Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ron, Geller"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Viral glycoproteins mediate entry into host cells, thereby dictating host range and pathogenesis. In addition, they constitute the principal target of neutralizing antibody responses, making them important antigens in vaccine development. Re
Externí odkaz:
https://doaj.org/article/5cf792bd1a544b67b52d3ace644dc0fb
Autor:
Ángela Sánchez-Simarro, Daniel Fernández-Soto, Brayan Grau, Eliseo Albert, Estela Giménez, Ana Isabel Avilés-Alía, Roberto Gozalbo-Rovira, Luciana Rusu, Beatriz Olea, Ron Geller, Hugh T. Reyburn, David Navarro
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The immune effector mechanisms involved in protecting against severe COVID-19 infection in elderly nursing home residents following vaccination or natural infection are not well understood. Here, we measured SARS-CoV-2 Spike (S)-directed fun
Externí odkaz:
https://doaj.org/article/a130eb88f682489f873bc05779fcfa72
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002709 (2024)
RNA viruses have notoriously high mutation rates due to error-prone replication by their RNA polymerase. However, natural selection concentrates variability in a few key viral proteins. To test whether this stems from different mutation tolerance pro
Externí odkaz:
https://doaj.org/article/35114a97011f45c5aa003c9936fc79e5
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Despite their fundamental role in resolving viral infections, our understanding of how polyclonal neutralizing antibody responses target non-enveloped viruses remains limited. To define these responses, we obtained the full antigenic profile
Externí odkaz:
https://doaj.org/article/ba12145d1f9947409ff27bc355448036
Autor:
Marina Rius-Salvador, Maria Jesús García-Múrria, Luciana Rusu, Manuel Bañó-Polo, Rubén León, Ron Geller, Ismael Mingarro, Luis Martinez-Gil
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297291 (2024)
BackgroundThe oral cavity is the site of entry and replication for many respiratory viruses. Furthermore, it is the source of droplets and aerosols that facilitate viral transmission. It is thought that appropriate oral hygiene that alters viral infe
Externí odkaz:
https://doaj.org/article/fd6f37fd8c7548c78d5d5cc2a9dd991a
Autor:
Christine Bäuerl, Joao Zulaica, Luciana Rusu, Alicia Rodríguez Moreno, Francisco J. Pérez-Cano, Carles Lerin, Desirée Mena-Tudela, Laia Aguilar-Camprubí, Anna Parra-Llorca, Cecilia Martínez-Costa, Ron Geller, Maria Carmen Collado
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106802- (2023)
Summary: Breastmilk contains antibodies that could protect breastfed infants from infections. In this work, we examined if antibodies in breastmilk could neutralize SARS-CoV-2 in 84 breastmilk samples from women that were either vaccinated (Comirnaty
Externí odkaz:
https://doaj.org/article/4c94f2d8a12543009e7328be27410fa3
Autor:
Beatriz Sánchez-Sendra, Eliseo Albert, Joao Zulaica, Ignacio Torres, Estela Giménez, Pilar Botija, María José Beltrán, Celia Rodado, Ron Geller, David Navarro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Immunosenescence may impact the functionality and breadth of vaccine-elicited humoral immune responses. The ability of sera to neutralize the SARS-CoV-2 spike protein (S) from Beta, Gamma, Delta, and Epsilon variants of concern (VOCs) relati
Externí odkaz:
https://doaj.org/article/fd94a4adb8234948b308be7eee9f1304
Autor:
Tiziana Ginex, Clara Marco-Marín, Miłosz Wieczór, Carlos P Mata, James Krieger, Paula Ruiz-Rodriguez, Maria Luisa López-Redondo, Clara Francés-Gómez, Roberto Melero, Carlos Óscar Sánchez-Sorzano, Marta Martínez, Nadine Gougeard, Alicia Forcada-Nadal, Sara Zamora-Caballero, Roberto Gozalbo-Rovira, Carla Sanz-Frasquet, Rocío Arranz, Jeronimo Bravo, Vicente Rubio, Alberto Marina, IBV-Covid19-Pipeline, Ron Geller, Iñaki Comas, Carmen Gil, Mireia Coscolla, Modesto Orozco, José Luis Llácer, Jose-Maria Carazo
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010995 (2022)
[This corrects the article DOI: 10.1371/journal.ppat.1010631.].
Externí odkaz:
https://doaj.org/article/ba2f6b5305b14bfdb18ac6c0d06dd810
Autor:
Tiziana Ginex, Clara Marco-Marín, Miłosz Wieczór, Carlos P Mata, James Krieger, Paula Ruiz-Rodriguez, Maria Luisa López-Redondo, Clara Francés-Gómez, Roberto Melero, Carlos Óscar Sánchez-Sorzano, Marta Martínez, Nadine Gougeard, Alicia Forcada-Nadal, Sara Zamora-Caballero, Roberto Gozalbo-Rovira, Carla Sanz-Frasquet, Rocío Arranz, Jeronimo Bravo, Vicente Rubio, Alberto Marina, IBV-Covid19-Pipeline, Ron Geller, Iñaki Comas, Carmen Gil, Mireia Coscolla, Modesto Orozco, José Luis Llácer, Jose-Maria Carazo
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010631 (2022)
The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation has since reappeared in the Delta subvariant AY.4.2, raising questions about its specific e
Externí odkaz:
https://doaj.org/article/2ac3186a08434f9d9f6e2286ac7350ff
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The replication machinery of most RNA viruses lacks proofreading mechanisms. As a result, RNA virus populations harbor a large amount of genetic diversity that confers them the ability to rapidly adapt to changes in their environment. In thi
Externí odkaz:
https://doaj.org/article/9c21002cc93c401dbeedb77867896e13