Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Romy Kirsten"'
Autor:
Solomon A. Sowah, Alessio Milanese, Ruth Schübel, Jakob Wirbel, Ece Kartal, Theron S. Johnson, Frank Hirche, Mirja Grafetstätter, Tobias Nonnenmacher, Romy Kirsten, Marina López-Nogueroles, Agustín Lahoz, Kathrin V. Schwarz, Jürgen G. Okun, Cornelia M. Ulrich, Johanna Nattenmüller, Arnold von Eckardstein, Daniel Müller, Gabriele I. Stangl, Rudolf Kaaks, Tilman Kühn, Georg Zeller
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background The gut microbiota has been suggested to play a significant role in the development of overweight and obesity. However, the effects of calorie restriction on gut microbiota of overweight and obese adults, especially over longer du
Externí odkaz:
https://doaj.org/article/b2a9d6f5ed5d4fb9a3a65f3eb76bef31
Autor:
Afshin Saffari, Claire Cannet, Astrid Blaschek, Andreas Hahn, Georg F. Hoffmann, Jessika Johannsen, Romy Kirsten, Musa Kockaya, Stefan Kölker, Wolfgang Müller-Felber, Andreas Roos, Hartmut Schäfer, Ulrike Schara, Manfred Spraul, Friedrich K. Trefz, Katharina Vill, Wolfgang Wick, Markus Weiler, Jürgen G. Okun, Andreas Ziegler
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Background 5q spinal muscular atrophy (SMA) is a disabling and life-limiting neuromuscular disease. In recent years, novel therapies have shown to improve clinical outcomes. Yet, the absence of reliable biomarkers renders clinical assessment
Externí odkaz:
https://doaj.org/article/d1420f1c464d4e51b184e3fd1fc57e55
Autor:
Sibylle Stoll, Solomon A. Sowah, Matthias A. Fink, Tobias Nonnenmacher, Mirja E. Graf, Theron Johnson, Christopher L. Schlett, Oyunbileg von Stackelberg, Romy Kirsten, Fabian Bamberg, Jeffrey Keller, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor, Fabian Rengier, Tilman Kühn, Johanna Nattenmüller
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Obesity-related metabolic disorders such as hypertension, hyperlipidemia and chronic inflammation have been associated with aortic dilatation and resulting in aortic aneurysms in many cases. Whether weight loss may reduce the risk of aortic dilatatio
Externí odkaz:
https://doaj.org/article/50071b72af794923a164fe080d0459c0
Autor:
Manuela Spurny, Yixin Jiang, Solomon A. Sowah, Tobias Nonnenmacher, Ruth Schübel, Romy Kirsten, Theron Johnson, Oyunbileg von Stackelberg, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor, Tilman Kühn, Johanna Nattenmüller
Publikováno v:
Nutrients, Vol 14, Iss 7, p 1437 (2022)
As the metabolic role of kidney fat remains unclear, we investigated the effects of dietary weight loss on kidney fat content (KFC) and its connection to kidney function and metabolism. Overweight or obese participants (n = 137) of a dietary interven
Externí odkaz:
https://doaj.org/article/1f79b323f10646f8870da988ddc32929
Autor:
Tilman Kühn, Tobias Nonnenmacher, Disorn Sookthai, Ruth Schübel, Daniel Antonio Quintana Pacheco, Oyunbileg von Stackelberg, Mirja E. Graf, Theron Johnson, Christopher L. Schlett, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor, Johanna Nattenmüller
Publikováno v:
BMC Gastroenterology, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Backround Non-alcoholic fatty liver disease (NAFLD) comprises non-progressive steatosis and non-alcoholic steatohepatitis (NASH), the latter of which may cause cirrhosis and hepatocellular carcinoma (HCC). As NAFLD detection is imperative fo
Externí odkaz:
https://doaj.org/article/458a5630dfae45abaf728beb99841d8b
Autor:
Manuela Spurny, Yixin Jiang, Solomon A. Sowah, Ruth Schübel, Tobias Nonnenmacher, Robert Bertheau, Romy Kirsten, Theron Johnson, Jens Hillengass, Christopher L. Schlett, Oyunbileg von Stackelberg, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor, Tilman Kühn, Johanna Nattenmüller
Publikováno v:
Nutrients, Vol 12, Iss 5, p 1509 (2020)
Background: Bone marrow fat is implicated in metabolism, bone health and haematological diseases. Thus, this study aims to analyse the impact of moderate weight loss on bone marrow fat content (BMFC) in obese, healthy individuals. Methods: Data of th
Externí odkaz:
https://doaj.org/article/baa5a406c0754719aad81a178f696a6d
Autor:
Solomon A. Sowah, Frank Hirche, Alessio Milanese, Theron S. Johnson, Mirja Grafetstätter, Ruth Schübel, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Georg Zeller, Tilman Kühn, Gabriele I. Stangl
Publikováno v:
Nutrients, Vol 12, Iss 2, p 452 (2020)
Gut microbial-derived short-chain fatty acids (SCFAs) may regulate energy homeostasis and exert anti-carcinogenic, immunomodulatory and anti-inflammatory effects. Smaller trials indicate that dietary weight loss may lead to decreased SCFA production,
Externí odkaz:
https://doaj.org/article/8afb17b30f30477d8ef540cbc49d8ee2
Autor:
Ruth Schübel, Tobias Nonnenmacher, Disorn Sookthai, Sandra Gonzalez Maldonado, Solomon A. Sowah, Oyunbileg von Stackelberg, Christopher L. Schlett, Mirja Grafetstätter, Diana Nabers, Theron Johnson, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Hans-Ulrich Kauczor, Tilman Kühn, Johanna Nattenmüller
Publikováno v:
Nutrients, Vol 11, Iss 3, p 544 (2019)
Background: Preliminary evidence suggests that weight loss among obese has differential metabolic effects depending on the presence of non-alcoholic fatty liver disease (NAFLD). We assessed whether NAFLD predisposes to differential changes in liver f
Externí odkaz:
https://doaj.org/article/895adadccaf049f88749313bfa423617
Autor:
Ruth Schübel, Disorn Sookthai, Judith Greimel, Theron S. Johnson, Mirja E. Grafetstätter, Romy Kirsten, Mario Kratz, Cornelia M. Ulrich, Rudolf Kaaks, Tilman Kühn
Publikováno v:
Nutrients, Vol 11, Iss 3, p 639 (2019)
Smaller cross-sectional studies and bariatric surgery trials suggest that weight loss may change the expression of genes in adipose tissue that have been implicated in the development of metabolic diseases, but well-powered intervention trials are la
Externí odkaz:
https://doaj.org/article/c1e6a2c119d943fab821c46e22bc8a07
Autor:
Wolfgang Müller-Felber, Manfred Spraul, A. Blaschek, Georg F. Hoffmann, Musa Kockaya, Claire Cannet, Jürgen G. Okun, Andreas Roos, Katharina Vill, Andreas Hahn, Friedrich K. Trefz, Afshin Saffari, Markus Weiler, Wolfgang Wick, Romy Kirsten, Hartmut Schäfer, Jessika Johannsen, Andreas Ziegler, Ulrike Schara, Stefan Kölker
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-16 (2021)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Background 5q spinal muscular atrophy (SMA) is a disabling and life-limiting neuromuscular disease. In recent years, novel therapies have shown to improve clinical outcomes. Yet, the absence of reliable biomarkers renders clinical assessment and prog