Zobrazeno 1 - 10
of 1 283
pro vyhledávání: '"Romosozumab"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract We aimed to investigate the efficacy of romosozumab treatment compared with that of denosumab in especially male osteoporosis patients. This retrospective cohort study included 174 Japanese male patients receiving either denosumab or romosoz
Externí odkaz:
https://doaj.org/article/5ccca53c681c493c810eec19cca479f5
Autor:
Ronald Man Yeung Wong, Pui Yan Wong, Chaoran Liu, Hei Yuet Wong, Man Ki Fong, Ning Zhang, Wing Hoi Cheung, Sheung Wai Law
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 107-122 (2024)
Background: Romosozumab is a novel monoclonal antibody that binds to sclerostin, and has dual effects of increasing bone formation and decreasing bone resorption, giving it a unique mechanism of action. The objective of this study was to perform a sy
Externí odkaz:
https://doaj.org/article/1d72d4d00968450b87c52ca245f98ee9
Autor:
Shruthi Reghunath, Roshni Ramesh, Raseena Beevi Nafeesa, Divya Purushothaman Visalakshy, Binitta Paul Kannappillil, Ambili Gopalakrishnan
Publikováno v:
Journal of Oral Research and Review, Vol 16, Iss 2, Pp 163-169 (2024)
Sclerostin is a glycoprotein predominantly released by specialized bone-forming cells (osteocytes). It serves as a principal inhibitor of osteogenesis and plays a key act in modulating the metabolism of alveolar bone. Sclerostin is shown to contribut
Externí odkaz:
https://doaj.org/article/2dcf7e58a40742039ca6aea127c356b2
Publikováno v:
Neurospine, Vol 21, Iss 2, Pp 416-429 (2024)
Objective We investigated the clinical efficacy of anabolic agents compared with bisphosphonates (BPs) for the incidence of new osteoporotic vertebral fracture (OVF) and fracture healing of OVF in the patients with OVF via meta-analyses of randomized
Externí odkaz:
https://doaj.org/article/0c1bb19a390943aa9909f2d34b99d744
Autor:
Maria L.R. Defante, Victoria Alzogaray, Davi Said Gonçalves Celso, Lucas Antônio Torres, Mayara Bearse, Ana Claudia Frota Machado de Melo Lopes
Publikováno v:
Osteoporosis and Sarcopenia, Vol 10, Iss 2, Pp 47-53 (2024)
Objectives: There are challenges for the treatment of osteoporosis in patients with kidney failure and monoclonal antibodies (MAb) might be a suitable therapy. However, the efficacy and safety of MAb among patients with osteoporosis and renal insuffi
Externí odkaz:
https://doaj.org/article/4cdc8db900864c718a882c9d9484ca67
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundPostmenopausal osteoporosis (PMOP) increases fracture risk in women. Though traditional treatments are slow to act, combining romosozumab with conventional therapy shows promise. Despite its growing use, studies on effectiveness are limited
Externí odkaz:
https://doaj.org/article/1cbeff0f2964449a89893a6055edc397
Autor:
Keishi Maruo, Tomoyuki Kusukawa, Masakazu Toi, Tetsuto Yamaura, Masaru Hatano, Hayato Oishi, Kazuma Nagao, Fumihiro Arizumi, Kazuya Kishima, Norichika Yoshie, Toshiya Tachibana
Publikováno v:
Bone Reports, Vol 21, Iss , Pp 101762- (2024)
Introduction: Domino osteoporotic vertebral fracture (OVF) is as a subsequent fracture that develops within 3 months before the initial OVF heals. There is limited evidence regarding the efficacy of osteoanabolic agents on its treatment. This study e
Externí odkaz:
https://doaj.org/article/60a35d12b45c44279c2b331e34e3ae6b
Autor:
Danbi Park, Seo Eun Kim, Hong Kyung Shin, Junghan Seo, Jeong Kyun Joo, Chongman Kim, Sang Hyub Lee, Jin Hoon Park
Publikováno v:
Neurospine, Vol 20, Iss 4, Pp 1217-1223 (2023)
Objective Romosozumab is increasingly employed to manage osteoporosis. However, no studies have analyzed its effects on recent osteoporotic vertebral compression fractures (OVCFs). Therefore, this study aimed to evaluate the efficacy of romosozumab c
Externí odkaz:
https://doaj.org/article/ef3fa1d33b834e45b3803c2e6b133143
Akademický článek
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Autor:
Matthias Tröltzsch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/2855def93bb44e9eb16d3e3ccd098183