A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects.

Autor: Kraig E; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Cell Systems and Anatomy, The University of Texas Health Science Center, San Antonio, USA. Electronic address: kraig@uthscsa.edu., Linehan LA; Department of Cell Systems and Anatomy, The University of Texas Health Science Center, San Antonio, USA., Liang H; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA., Romo TQ; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; GRECC, South Texas Veterans Health Care System, The University of Texas Health Science Center, San Antonio, USA., Liu Q; Department of Epidemiology and Biostatistics, The University of Texas Health Science Center, San Antonio, USA., Wu Y; Department of Medicine, The University of Texas Health Science Center, San Antonio, USA., Benavides AD; Department of Microbiology, Immunology, and Molecular Genetics, The University of Texas Health Science Center, San Antonio, USA., Curiel TJ; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Medicine, The University of Texas Health Science Center, San Antonio, USA., Javors MA; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Psychiatry, The University of Texas Health Science Center, San Antonio, USA., Musi N; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Medicine, The University of Texas Health Science Center, San Antonio, USA; GRECC, South Texas Veterans Health Care System, The University of Texas Health Science Center, San Antonio, USA., Chiodo L; GRECC, South Texas Veterans Health Care System, The University of Texas Health Science Center, San Antonio, USA., Koek W; Department of Cell Systems and Anatomy, The University of Texas Health Science Center, San Antonio, USA; Department of Psychiatry, The University of Texas Health Science Center, San Antonio, USA., Gelfond JAL; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Epidemiology and Biostatistics, The University of Texas Health Science Center, San Antonio, USA., Kellogg DL Jr; Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, USA; Department of Medicine, The University of Texas Health Science Center, San Antonio, USA; GRECC, South Texas Veterans Health Care System, The University of Texas Health Science Center, San Antonio, USA.

Publikováno v: Experimental gerontology [Exp Gerontol] 2018 May; Vol. 105, pp. 53-69. Date of Electronic Publication: 2018 Feb 03.