Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Romney M, Humphries"'
Autor:
Jeffrey A. Freiberg, Connor R. Deri, Whitney J. Nesbitt, Romney M. Humphries, George E. Nelson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT The use of molecular-based diagnostic testing, such as the Luminex Verigene system, to rapidly identify the most common bacterial isolates from blood cultures is an important tool that reduces the duration of inappropriate antibiotics and de
Externí odkaz:
https://doaj.org/article/0338e46b9cbd4dffa124832fda60d2e8
Publikováno v:
Journal of Clinical Microbiology. 61
Publikováno v:
Clinical Infectious Diseases. 76:1868-1870
Publikováno v:
Journal of Clinical Microbiology.
Antibacterial susceptibility testing (AST) is performed to guide therapy, perform resistance surveillance studies, and support development of new antibacterial agents. For 5 decades, broth microdilution (BMD) has served as the reference method to ass
Autor:
Romney M. Humphries, Eugene Bragin, Julian Parkhill, Grace Morales, Jonathan E. Schmitz, Paul A. Rhodes
The declining cost of performing bacterial whole-genome sequencing (WGS) coupled with the availability of large libraries of sequence data for well-characterized isolates have enabled the application of machine-learning (ML) methods to the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5c66bf274985a48c1360d232615a59
https://www.repository.cam.ac.uk/handle/1810/349213
https://www.repository.cam.ac.uk/handle/1810/349213
Publikováno v:
Open Forum Infectious Diseases. 10
Increasing parechovirus (PeV) infections prompted a Centers for Disease Control and Prevention Health Advisory in July 2022. We retrospectively assessed national PeV trends in cerebrospinal fluid and observed unexpected viral dynamics from 2020 to 20
Autor:
Carmila Manuel, Richard Maynard, April Abbott, Kara Adams, Kevin Alby, Amy Sweeney, Jennifer Dien Bard, Irvin Ibarra Flores, Violet Rekasius, Amanda Harrington, Tiffany S. Kidd, Amy J. Mathers, Tsigereda Tekle, Patricia J. Simner, Romney M. Humphries
Publikováno v:
Journal of Clinical Microbiology. 61
In 2022, the Clinical and Laboratory Standards Institute (CLSI) updated piperacillin-tazobactam (TZP) breakpoints for Enterobacterales , based on substantial data suggesting that historical breakpoints did not predict treatment outcomes for TZP. The
Publikováno v:
J Clin Microbiol
Globally, piperacillin-tazobactam resistance among Escherichia coli and Klebsiella pneumoniae is driven by OXA-1 beta-lactamases. Expression of bla(OXA-1) yields piperacillin-tazobactam MICs of 8 to 16 μg/mL, which straddle the susceptible/susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa181c6760948a7537d7127a3e509c9f
https://europepmc.org/articles/PMC9769679/
https://europepmc.org/articles/PMC9769679/
Autor:
Nathan Mullen, Hugo Raposo, Polyxeni Gudis, Linsey Barker, Romney M. Humphries, Bryan H. Schmitt, Ryan F. Relich, Meghan May
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT Antimicrobial susceptibility testing of clinical isolates is a crucial step toward appropriate treatment of infectious diseases. The clinical isolate Francisella philomiragia 14IUHPL001, recently isolated from a 63-year-old woman with atypic
Externí odkaz:
https://doaj.org/article/d5862d1c06454700bce2c4bcbfd189a7
Publikováno v:
Clinical Microbiology Newsletter. 43:97-107
The fluoroquinolones are a commonly prescribed class of antibiotics with broad activity across a variety of bacteria. As an antimicrobial class, the fluoroquinolones exert antimicrobial activity by direct inhibition of DNA synthesis due to interactio