Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rommel Morales"'
Autor:
Yong-Hyun Kim, Takeshi Kitai, Rommel Morales, Kathryn Kiefer, Thanat Chaikijurajai, W. H. Wilson Tang
Publikováno v:
The American Journal of Cardiology. 176:73-78
The surface layer of endothelium contains the endothelial glycocalyx (eGC), consisting of proteoglycan polymers. Syndecan-1, heparan sulfate, and hyaluronic acid are major constituents of eGC, and their increasing detection in serum represents active
Autor:
Takeshi Kitai, Ina Nemet, Timothy Engelman, Rommel Morales, Thanat Chaikijurajai, Kathryn Morales, Stanley L. Hazen, W.H. Wilson Tang
Publikováno v:
American Heart Journal. 245:78-80
We prospectively performed serial differential sugar absorption test in 29 consecutively consented patients with advanced decompensated heart failure admitted to the heart failure intensive care unit for hemodynamically-guided therapy. We observed th
The IgG3 subclass of β1-adrenergic receptor autoantibodies is an endogenous biaser of β1AR signaling
Autor:
Timothy Engelman, Sromona D Mukherjee, Rommel Morales, Maradumane L. Mohan, W.H. Wilson Tang, Yuji Nagatomo, Stanley L. Hazen, Sathyamangla V. Naga Prasad, Prasenjit Prasad Saha
Publikováno v:
Molecular Biology of the Cell
Dysregulation of immune responses has been linked to the generation of immunoglobulin G (IgG) autoantibodies that target human β1ARs and contribute to deleterious cardiac outcomes. Given the benefits of β-blockers observed in patients harboring the
Autor:
Rommel Morales, Maradumane L. Mohan, Sromona Mukherjee, Sathyamangla V. Naga Prasad, Timothy Engelman, Yuji Nagatomo, W.H. Wilson Tang
Autoantibodies recognizing human {beta}1ARs generated due to dysregulation in autoimmune response are generally associated with deleterious cardiac outcomes. However, cellular studies show that isolates of {beta}1AR autoantibody from patients differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ab25abe23f9db73316769eb4fc66468
https://doi.org/10.1101/2020.09.17.302059
https://doi.org/10.1101/2020.09.17.302059
Autor:
Christine S. Moravec, Kayla Mislick, Andre Klaassen Kamdar, Srinivasa T. Reddy, David J. Kennedy, Xi Wang, Brendan Agatisa-Boyle, Rommel Morales, Malory E. Weber, Diana M. Shih, Zhili Shao, Wei Li, W.H. Wilson Tang, Kathryn Kiefer
Publikováno v:
Free Radical Biology and Medicine. 121:117-126
Background Mitochondrial oxidation is a major source of reactive oxygen species (ROS) and mitochondrial dysfunction plays a central role in development of heart failure (HF). Paraoxonase 2 deficient (PON2-def) mitochondria are impaired in function. I
Autor:
W.H. Wilson Tang, Rommel Morales, Takeshi Kitai, Yong Hyun Kim, Thanat Chaikijurajai, Kathryn Morales
Publikováno v:
Journal of Cardiac Failure. 26:S15-S16
Introduction Endothelial glycocalyx (eGC) contains proteoglycan polymers, such as syndecan-1, heparan sulfate (HS), and hyaluronic acid (HA), which play an important role in protecting endothelial cells from inflammatory cells and cytokines, as well
Autor:
W.H. Wilson Tang, Xavier F. Jimenez, David O. Taylor, J. Bradley Williams, Shamanthika Shelkay, Richard W. Rosenquist, Rommel Morales, Dmitry M. Yaranov, Kimberly Miracle, Kay Kendall, Edward G. Soltesz
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 39(9)
Circulating Osteocrin Levels Do Not Track with Myocardial Function in Chronic Systolic Heart Failure
Publikováno v:
Journal of Cardiac Failure. 26:S20
Background Osteocrin was originally classified as a muscular and bone secretory protein with the ability to modulate bone growth through osteoblast activity, yet it shares a similar sequence to the family of natriuretic peptides (NPs). Despite their
Autor:
Anjli Maroo, W.H. Wilson Tang, Allyson Zabell, Praful V. Maroo, Yogesh G. Shah, Tracy Kovach, Brendan Sheehy, Sangithan Jules Moodley, Meera Kumari, Rommel Morales
Publikováno v:
Clin Biochem
BACKGROUND Corin is a serine protease known to convert B-type natriuretic peptide (BNP) prohormone into BNP and its amino-terminal fragment (NT-proBNP). In mice lacking corin, high blood pressure and proteinuria were found at late gestational stages,
Autor:
George E. Havelka, Melina R. Kibbe, Nadiezhda Cantu-Medellin, Eric E. Kelley, Rommel Morales, Edward Moreira Bahnson
Publikováno v:
Redox Biology, Vol 4, Iss C, Pp 226-233 (2015)
Redox Biology
Redox Biology
Background Nitric oxide (•NO) is more effective at inhibiting neointimal hyperplasia following arterial injury in male versus female rodents, though the etiology is unclear. Given that superoxide (O2•−) regulates cellular proliferation, and •