Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rommel Mallari"'
Autor:
Rommel Mallari, Edwin Paming
Publikováno v:
JPAIR, Vol 42, Iss 1, Pp 53-62 (2020)
Ang pag-aaral na ito ay isasagawa upang maalaman ang “Isang Pagsisiyasat sa mga Akdang Pampanitikan sa Ikaapat na Antas ng Batsilyer ng Elementarya at Edukasyon sa Paglinang ng mga Pilosopiyang Likas at Pagpapahalagang Moral na Ginagamit sa Pagtutu
Externí odkaz:
https://doaj.org/article/2f1c818850134410a9cb1b86c83d52d4
Autor:
Gwenaella Rescourio, Ana Z. Gonzalez, Salman Jabri, Brian Belmontes, Gordon Moody, Doug Whittington, Xin Huang, Sean Caenepeel, Mario Cardozo, Alan C. Cheng, David Chow, Hannah Dou, Adrie Jones, Ron C. Kelly, Yihong Li, Mike Lizarzaburu, Mei-Chu Lo, Rommel Mallari, Cesar Meleza, Yosup Rew, Scott Simonovich, Daqing Sun, Simon Turcotte, Xuelei Yan, Simon G. Wong, Evelyn Yanez, Manuel Zancanella, Jonathan Houze, Julio C. Medina, Paul E. Hughes, Sean P. Brown
Publikováno v:
Journal of Medicinal Chemistry. 62:10258-10271
Overexpression of the antiapoptotic protein Mcl-1 provides a survival advantage to some cancer cells, making inhibition of this protein an attractive therapeutic target for the treatment of certain types of tumors. Herein, we report our efforts towar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e56bfd1df312774368ff5b90efcd7cc
https://doi.org/10.1021/acs.jmedchem.9b01310
https://doi.org/10.1021/acs.jmedchem.9b01310
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(2)
Since the revolutionary discovery of RNA interference (RNAi) more than 20 years ago, synthetic small interfering RNAs (siRNAs) have held great promise as therapeutic agents for treating human diseases by the specific knockdown of disease-causing gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4b5df416fe6b8a58b37efc4850613f
https://pubmed.ncbi.nlm.nih.gov/33016168
https://pubmed.ncbi.nlm.nih.gov/33016168
Supplemental material, Supplemental_Material_FISH_Dou_et_al for An Automated High-Throughput Fluorescence In Situ Hybridization (FISH) Assay Platform for Use in the Identification and Optimization of siRNA-Based Therapeutics by Hui H. Dou, Rommel Mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090d776c0c91cc7f0f381e150524036d
Publikováno v:
SLAS Discovery. 8:198-204
A generic high-throughput screening assay based on the scintillation proximity assay technology has been developed for protein kinases. In this assay, the biotinylated (33)P-peptide product is captured onto polylysine Ysi bead via avidin. The scintil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8da8e6912477acd384cf2e899f7c2c
https://doi.org/10.1177/1087057103252306
https://doi.org/10.1177/1087057103252306
Autor:
Ian Foltz, Jennifer J. Kordich, Julia C. Piasecki, Thu Dang, Jonathan David Graves, John M. Rossi, Daniel Branstetter, Tzu-Hsuan Huang, Heather Douangpanya, Timothy J. Sullivan, Alexander M. Long, Wesley Chang, Xiaoning Zhao, Rommel Mallari, Xin Huang, Jason W. O'Neill, Pamela M. Holland, Tammy L. Bush
Publikováno v:
Cancer cell. 26(2)
SummaryDeath receptor agonist therapies have exhibited limited clinical benefit to date. Investigations into why Apo2L/TRAIL and AMG 655 preclinical data were not predictive of clinical response revealed that coadministration of Apo2L/TRAIL with AMG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf1740040e409bf2ef4eb812b916eeb
https://pubmed.ncbi.nlm.nih.gov/25043603
https://pubmed.ncbi.nlm.nih.gov/25043603
Autor:
Shu-Chen Lu, Soo Hang Wong, Wei Gu, Paul H. Lee, Melissa Graham, Larissa Atangan, Xiaoning Zhao, Rommel Mallari
Publikováno v:
Assay and drug development technologies. 8(4)
Lysophosphatidic acid (LPA) is a bioactive phospholipid that signals through G-protein-coupled receptors to produce a range of biological responses. A recently reported LPA receptor GPR23 (LPA4 receptor) has a low homology to the LPA(1-3) receptors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37d9b689f05044fce8cdcbd7ddafaed
https://pubmed.ncbi.nlm.nih.gov/20482379
https://pubmed.ncbi.nlm.nih.gov/20482379
Autor:
Shou-Hua Xiao, Adam Park, Keith R. Olson, Adrie D. Jones, Stephen W. Young, Danilo Nebalasca, Rommel Mallari, Kun Peng, Tom S. Wehrman, Xiaoning Zhao
Publikováno v:
Journal of biomolecular screening. 13(8)
G-protein-coupled receptors (GPCRs) represent one of the largest gene families in the human genome and have long been regarded as valuable targets for small-molecule drugs. The authors describe a new functional assay that directly monitors GPCR activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7140f579460e439cc3d83cc08117335
https://pubmed.ncbi.nlm.nih.gov/18660457
https://pubmed.ncbi.nlm.nih.gov/18660457
Autor:
Soo Hang Wong, Rommel Mallari, Melissa Graham, Larissa Atangan, Shu-Chen Lu, Xiaoning Zhao, Wei Gu, Paul H. Lee
Publikováno v:
Assay & Drug Development Technologies; Aug2010, Vol. 8 Issue 4, p459-470, 12p