Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Rommel A. Mathias"'
Autor:
Caroline L. Ashley, Brian P. McSharry, Hamish E. G. McWilliam, Richard J. Stanton, Ceri A. Fielding, Rommel A. Mathias, David P. Fairlie, James McCluskey, Jose A. Villadangos, Jamie Rossjohn, Allison Abendroth, Barry Slobedman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells (MAIT cells).MethodsT
Externí odkaz:
https://doaj.org/article/53babfbfbc814e488fc54d15c6f86de6
Autor:
Declan L. Turner, Rommel A. Mathias
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Human cytomegalovirus (HCMV) is a ubiquitous human pathogen that can cause severe disease in immunocompromised individuals, transplant recipients, and to the developing foetus during pregnancy. There is no protective vaccine currently available, and
Externí odkaz:
https://doaj.org/article/49b7ed0d06fa4fa8ae09d96aa7507c1d
Autor:
Declan L. Turner, Svenja Fritzlar, Sara Sadeghipour, Adele A. Barugahare, Brendan E. Russ, Stephen J. Turner, Rommel A. Mathias
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105168- (2022)
Summary: More than half the world’s population is infected with human cytomegalovirus (HCMV), causing congenital birth defects and impacting the immuno-compromised. Many of the >170 HCMV genes remain uncharacterized, and this gap in knowledge limit
Externí odkaz:
https://doaj.org/article/d3d3183e099843a985101a7dec9804bf
Autor:
Declan L. Turner, Rachel M. Templin, Adele A. Barugahare, Brendan E. Russ, Stephen J. Turner, Georg Ramm, Rommel A. Mathias
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5773 (2022)
Over 50% of the world’s population is infected with Human Cytomegalovirus (HCMV). HCMV is responsible for serious complications in the immuno-compromised and is a leading cause of congenital birth defects. The molecular function of many HCMV protei
Externí odkaz:
https://doaj.org/article/89fc41e3f8924726b5a5c91d901299a0
Autor:
Callum J. Vidor, Audrey Hamiot, Jessica Wisniewski, Rommel A. Mathias, Bruno Dupuy, Milena Awad, Dena Lyras
Publikováno v:
Toxins, Vol 14, Iss 2, p 124 (2022)
Protein secretion is generally mediated by a series of distinct pathways in bacteria. Recently, evidence of a novel bacterial secretion pathway involving a bacteriophage-related protein has emerged. TcdE, a holin-like protein encoded by toxigenic iso
Externí odkaz:
https://doaj.org/article/c599de286eeb402298634a248bbe8fc1
Autor:
Callum J, Vidor, Audrey, Hamiot, Jessica, Wisniewski, Rommel A, Mathias, Bruno, Dupuy, Milena, Awad, Dena, Lyras
Publikováno v:
Toxins. 14(2)
Protein secretion is generally mediated by a series of distinct pathways in bacteria. Recently, evidence of a novel bacterial secretion pathway involving a bacteriophage-related protein has emerged. TcdE, a holin-like protein encoded by toxigenic iso
Autor:
Bow J. Tauro, David W. Greening, Rommel A. Mathias, Hong Ji, Richard J. Simpson, Suresh Mathivanan
Exosomes are naturally occurring biological nanomembranous vesicles (̃40 to 100 nm) of endocytic origin that are released from diverse cell types into the extracellular space. They have pleiotropic functions such as antigen presentation and intercel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7e0c31134d78758a9f3c1154801642
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Human Cytomegalovirus (HCMV) infects over half the world's population, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals. To expand the molecular knowledge governing virion maturation, we analy
Autor:
Eric Hanssen, David W. Greening, Richard J. Simpson, Hong-Jian Zhu, Rommel A. Mathias, Shashi K. Gopal
Publikováno v:
Oncotarget
The metastatic cascade describes the escape of primary tumour cells to distant secondary sites. Cells at the leading tumour edge are thought to undergo epithelial-mesenchymal transition (EMT), to enhance their motility and invasion for spreading. Whe