Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Romina Wechsel"'
Publikováno v:
Angewandte Chemie. 128:9809-9813
Publikováno v:
Wechsel, R, Ward, J W, Clayden, J & Zabka, M 2018, ' Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer : A Molecular Spring Torsion Balance ', Journal of the American Chemical Society, vol. 140, no. 10, pp. 3528-3531 . https://doi.org/10.1021/jacs.8b00567
Symmetrical oligourea foldamers were made from meso cyclohexane-1,2-diamine and desymmetrised by incorporating terminal functional groups (carbamates, ureas or thioureas) with differing hydrogen-bonding capacities. Irrespective of solvent, the foldam
Publikováno v:
Wechsel, R, Raftery, J, Cavagnat, D, Guichard, G & Clayden, J 2016, ' The meso Helix : Symmetry and Symmetry-Breaking in Dynamic Oligourea Foldamers with Reversible Hydrogen-Bond Polarity ', Angewandte Chemie-International Edition, vol. 55, no. 33, pp. 9657-9661 . https://doi.org/10.1002/anie.201604496
Oligoureas (up to n=6) of meso cyclohexane-1,2-diamine were synthesized by chain extension with an enzymatically desymmetrized monomer 2. Despite being achiral, the meso oligomers adopt chiral canonical 2.5-helical conformations, the equally populate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37ab15ea9c1b75be6f71e9bdd17f8a9
https://research-information.bris.ac.uk/en/publications/c001387e-b0b2-4f4d-97aa-14ed467eb781
https://research-information.bris.ac.uk/en/publications/c001387e-b0b2-4f4d-97aa-14ed467eb781
Autor:
Romina Wechsel, Julien Maury, Juliette Fremaux, Scott P. France, Gilles Guichard, Jonathan Clayden
Publikováno v:
Chemical communications (Cambridge, England). 50(95)
The ability of urea-linked oligomers of achiral diamines (achiral analogues of the well-established chiral oligourea foldamers) to adopt helical conformations was explored spectroscopically. Up to four achiral units were ligated either to a well-form
Autor:
Jonathan D. Beadle, Jordi Solà, Alejandro Castellanos, Thomas Boddaert, Robert A. Brown, Romina Wechsel, Jonathan Clayden, Liam Byrne, Matteo De Poli
Publikováno v:
De Poli, M, Byrne, L, Brown, R A, Solà, J, Castellanos, A, Boddaert, T, Wechsel, R, Beadle, J D & Clayden, J 2014, ' Engineering the structure of an N-terminal β-turn to maximize screw-sense preference in achiral helical peptide chains ', Journal of Organic Chemistry, vol. 79, no. 10, pp. 4659-4675 . https://doi.org/10.1021/jo500714b
Oligomers of α-aminoisobutyric acid (Aib) are achiral peptides that typically adopt 310 helical conformations in which enantiomeric left- and right-handed conformers are, necessarily, equally populated. Incorporating a single protected chiral residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00173acaec34d7ed0bc35793d73f8665
https://www.ccdc.cam.ac.uk/structures/search?id=doi:10.5517/cc11yx52&sid=DataCite
https://www.ccdc.cam.ac.uk/structures/search?id=doi:10.5517/cc11yx52&sid=DataCite