Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Romina S. Goldszmid"'
Autor:
Amélie, Lopès, Romina S, Goldszmid
Publikováno v:
Immunity. 55:582-585
Immune checkpoint blockade has dramatically improved cancer therapy but remains ineffective for most colorectal tumors. In this issue of Immunity, Peuker et al. describe a microbiota-myeloid-tumor cell crosstalk that inhibits CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce8d9808303b7e751b38fde39a8b65a
https://doi.org/10.1016/j.immuni.2022.03.011
https://doi.org/10.1016/j.immuni.2022.03.011
Autor:
Amélie Lopès, Jessica Rappaport, Eva Pérez Guijarro, Quanyi Chen, Emily Wu, Isabella Church, April Huang, Jessica Bridge, Sung Chin, Cari Smith, Charli Gruen, Khiem C. Lam, Romina E. Araya, Antonella Sassano, Chi-Ping Day, Glenn Merlino, Romina S. Goldszmid
Publikováno v:
Cancer Research. 83:5188-5188
Brain metastases (BrM) remain an intractable, deadly complication for advanced melanoma patients and efficient therapeutic strategies are desperately needed. The tumor microenvironment (TME) plays an important role in response to therapy. However, st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473556e4dd1dcf33b7a2f05787564c65
https://doi.org/10.1158/1538-7445.am2023-5188
https://doi.org/10.1158/1538-7445.am2023-5188
Autor:
Khiem C. Lam, Romina S. Goldszmid
Publikováno v:
Cancer Cell. 39:1314-1316
A recent report in Nature Medicine pinpoints a role for gut microbiota in response and toxicity to combined immune checkpoint blockade targeting CTLA-4 and PD-1. This emergent study provides insights that can be used to leverage microbiota in the des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce638515607d9c283324b1b06baca4e3
https://doi.org/10.1016/j.ccell.2021.09.013
https://doi.org/10.1016/j.ccell.2021.09.013
Autor:
Jennifer A. Wargo, Giorgio Trinchieri, Kenya Honda, Romina S. Goldszmid, Laurence Zitvogel, B. Brett Finlay
Publikováno v:
Nature Reviews Immunology
There is currently much interest in defining how the microbiota shapes immune responses in the context of cancer. Various studies in both mice and humans have associated particular commensal species with better (or worse) outcomes in different cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803ccbd51c1062f93b389902028e6380
https://doi.org/10.1038/s41577-020-0374-6
https://doi.org/10.1038/s41577-020-0374-6
Autor:
Chi-Ping Day, Eva Pérez-Guijarro, Amélie Lopès, Romina S. Goldszmid, Meera Murgai, Lalage Wakefield, Glenn Merlino
Publikováno v:
Cancer Cell. 40:231-232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db45773dc288c74e507edd415e474e5e
https://doi.org/10.1016/j.ccell.2022.01.015
https://doi.org/10.1016/j.ccell.2022.01.015
Autor:
Romina E Araya, Khiem C Lam, April Huang, Quanyi Chen, Martina Di Modica, Amelie Lopes, Howard Yang, Huaitian Liu, Maxwell P. Lee, Romina S. Goldszmid
Publikováno v:
The Journal of Immunology. 208:120.03-120.03
Neutrophils play an important role in cancer progression and both pro- and antitumorigenic functions have been described. However, their role in response to therapy and whether environmental signals modulate their function in the tumor microenvironme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ee4639f23fe59ffc0f748ce3ec95cd8
https://doi.org/10.4049/jimmunol.208.supp.120.03
https://doi.org/10.4049/jimmunol.208.supp.120.03
Publikováno v:
The Journal of Immunology. 208:120.08-120.08
Gut microbiota impacts antitumor immunity and recent studies have shown that manipulating microbiota via fecal transplant can rescue immune checkpoint blockade (ICB) response in refractory melanoma patients. However, not all patients benefited from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcb78727f9e4727d289863e555a23487
https://doi.org/10.4049/jimmunol.208.supp.120.08
https://doi.org/10.4049/jimmunol.208.supp.120.08
Autor:
Roger S. Lo, Khiem C. Lam, Maxwell P. Lee, Aleksandra M. Michalowski, Eva Pérez-Guijarro, Romina S. Goldszmid, Howard H. Yang, Romina E. Araya, Glenn Merlino, Terry Van Dyke, Rajaa El Meskini, Alan Kulaga, Helen T. Michael, Chi-Ping Day, Nicholas P. Restifo, Willy Hugo, Zoe Weaver Ohler, Shyam K. Sharan, Suman K. Vodnala, Sung Chin, Kerrie L. Marie, Anthony J. Iacovelli, Anyen Fon, Andres Thorkelsson, Cari Smith
Publikováno v:
Nat Med
Although immunotherapy has revolutionized cancer treatment, only a subset of patients demonstrate durable clinical benefit. Definitive predictive biomarkers and targets to overcome resistance remain unidentified, underscoring the urgency to develop r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1ec36e5bc84e0bf67987f72cd8b005
https://europepmc.org/articles/PMC8482620/
https://europepmc.org/articles/PMC8482620/
Autor:
Romina E. Araya, Romina S. Goldszmid
Publikováno v:
Methods Enzymol
The tumor microenvironment (TME) is a highly complex and dynamic ensemble of cells of which a variety of immune cells are a major component. The unparalleled results obtained with immunotherapeutic approaches have underscored the importance of examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cd0f8f58da73cff31945645d411303
https://pubmed.ncbi.nlm.nih.gov/32000903
https://pubmed.ncbi.nlm.nih.gov/32000903
Autor:
Joshua K. Stone, Araya Romina, Natalia von Muhlinen, Chenran Zhang, Romina S. Goldszmid, Curtis C. Harris
Publikováno v:
Cancer Research. 81:1782-1782
Lung cancer is the most common cause of cancer-related death worldwide in both men and women. The overall survival of lung cancer remains poor due to limitations in diagnostic and therapeutic strategies. Therefore, the development of novel biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ccf195a1de81d4184bafa01f8af5543
https://doi.org/10.1158/1538-7445.am2021-1782
https://doi.org/10.1158/1538-7445.am2021-1782