Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Romina Ponzielli"'
Autor:
Manpreet Kalkat, Pak-Kei Chan, Amanda R Wasylishen, Tharan Srikumar, Sam S Kim, Romina Ponzielli, David P Bazett-Jones, Brian Raught, Linda Z Penn
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115337 (2014)
The c-MYC transcription factor is a master regulator of many cellular processes and deregulation of this oncogene has been linked to more than 50% of all cancers. This deregulation can take many forms, including altered post-translational regulation.
Externí odkaz:
https://doaj.org/article/36543a850d5a4a229521ec2c61e6d4e2
Autor:
Linda Z. Penn, Cynthia E. Hawkins, Daniel Picard, Eric Bouffet, Dalia Barsyte-Lovejoy, Romina Ponzielli, Cynthia S.W. Ho, Annie Huang
Supplementary Figure 1 from Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e667c93eb7b70492a9829410678ed00
https://doi.org/10.1158/0008-5472.22364415
https://doi.org/10.1158/0008-5472.22364415
Autor:
Linda Z. Penn, Cynthia E. Hawkins, Daniel Picard, Eric Bouffet, Dalia Barsyte-Lovejoy, Romina Ponzielli, Cynthia S.W. Ho, Annie Huang
c-myc oncogene activation is critical in the pathogenesis of a spectrum of human malignancies. The c-Myc NH2-terminal domain (MycNTD) is essential for cellular transformation, and mediates critical protein interactions that modulate c-Myc oncogenic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9d5ce1dc0641ce5dae1e3bccee6597
https://doi.org/10.1158/0008-5472.c.6494181
https://doi.org/10.1158/0008-5472.c.6494181
Autor:
Angelina Stojanova, Pak-Kei Chan, Linda Z. Penn, Fereshteh Khosravi, Brian Raught, William B. Tu, Paul C. Boutros, Max Kotlyar, Igor Jurisica, Romina Ponzielli
Publikováno v:
Cell Cycle
Cell cycle (Georgetown, Tex.), vol 15, iss 13
Cell cycle (Georgetown, Tex.), vol 15, iss 13
MYC is a key driver of cellular transformation and is deregulated in most human cancers. Studies of MYC and its interactors have provided mechanistic insight into its role as a regulator of gene transcription. MYC has been previously linked to chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718565ebe6877ec1eee02a8d1340d0dd
https://doi.org/10.1080/15384101.2016.1146836
https://doi.org/10.1080/15384101.2016.1146836
Autor:
Dharmendra Dingar, Lindsay C. Lustig, Ichiro Inamoto, William B. Tu, Jumi A. Shin, Corey Lourenco, Manpreet Kalkat, Warren C. W. Chan, Linda Z. Penn, Romina Ponzielli
Publikováno v:
Oncogene. 36(49)
Developing therapeutics to effectively inhibit the MYC oncoprotein would mark a key advance towards cancer patient care as MYC is deregulated in over 50% of human cancers. MYC deregulation is correlated with aggressive disease and poor patient outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5c65d6cd55e7c3698f6301b6c54035
https://pubmed.ncbi.nlm.nih.gov/28806396
https://pubmed.ncbi.nlm.nih.gov/28806396
Autor:
Jumi A. Shin, Warren W.C Chan, Sarmitha Sathiamoorthy, Ichiro Inamoto, Linda Z. Penn, Peter S. Tang, Romina Ponzielli, Lindsay C. Lustig
Publikováno v:
Future Science OA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03ea1fd82b0e9aaa50c0d01d7601391
https://doi.org/10.4155/fso.15.1
https://doi.org/10.4155/fso.15.1
Publikováno v:
European Journal of Cancer. 41:2485-2501
The potent Myc oncoprotein plays a pivotal role as a regulator of tumorigenesis in numerous human cancers of diverse origin. Experimental evidence shows that inhibiting Myc significantly halts tumour cell growth and proliferation. This review summari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bf05f82a0fa05bbe2c038675125c80
https://doi.org/10.1016/j.ejca.2005.08.017
https://doi.org/10.1016/j.ejca.2005.08.017
Autor:
Eric Bouffet, Cynthia S.W. Ho, Dalia Barsyte-Lovejoy, Romina Ponzielli, Cynthia Hawkins, Daniel Picard, Annie Huang, Linda Z. Penn
Publikováno v:
Cancer Research. 65:5607-5619
c-myc oncogene activation is critical in the pathogenesis of a spectrum of human malignancies. The c-Myc NH2-terminal domain (MycNTD) is essential for cellular transformation, and mediates critical protein interactions that modulate c-Myc oncogenic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb891196de9d3bc1f835e2ae2cbbce7
https://doi.org/10.1158/0008-5472.can-05-0500
https://doi.org/10.1158/0008-5472.can-05-0500
Publikováno v:
Developmental Biology
Developmental Biology, Elsevier, 2004, 272, pp.419-431
Developmental Biology, 2004, 272, pp.419-431
HAL
Developmental Biology, Elsevier, 2004, 272, pp.419-431
Developmental Biology, 2004, 272, pp.419-431
HAL
The segmented Drosophila linear cardiac tube originates from two cell lineages that give rise to the anterior aorta (AA) and the posterior cardiac tube. The three Hox genes of the Bithorax Complex as well as Antennapedia (Antp) have been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb07a6e440834849efed9ec4b810fb7
https://doi.org/10.1016/j.ydbio.2004.04.036
https://doi.org/10.1016/j.ydbio.2004.04.036
Publikováno v:
Journal de la Société de Biologie. 197:161-168
Chez la Drosophile, le cœur est un simple tube lineaire, le tube cardiaque, forme a partir de 52 paires de cellules myoendotheliales, qui, en fin d’embryogenese, se differencient pour donner un organe fonctionnel. C’est un organe pulsatile, a ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::809a68466d184eff7340fc2098c404b6
https://doi.org/10.1051/jbio/2003197020161
https://doi.org/10.1051/jbio/2003197020161