Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Romina Paula Bulacio"'
Erythropoietin alters the pharmacokinetics of organic anions mainly eliminated by the kidney in rats
Autor:
María Herminia Hazelhoff, María Julia Severin, Adriana M. Torres, Anabel Brandoni, María E. Mamprin, Romina Paula Bulacio
Publikováno v:
Canadian journal of physiology and pharmacology. 99(4)
Erythropoietin (EPO) is a cytokine originally used for its effects on the hematopoietic system, and is widely prescribed around the world. In the present study, the effects of EPO administration on p-aminohippurate (PAH, a prototype organic anion) ph
Publikováno v:
Pharmacology. 106(5-6)
Introduction: The presence of mercury in the environment is a worldwide concern. Inorganic mercury is present in industrial materials, is employed in medical devices, is widely used in batteries, is a component of fluorescent light bulbs, and it has
Publikováno v:
Toxicology letters. 313
Acute kidney injury (AKI) is a heterogeneous clinical syndrome with diverse outcomes. The recovery from AKI has prognostic importance. Little research has been done in order to find biomarkers that can predict recovery from AKI. Cav-2 is one of the m
Mercuric ions (Hg+2) gain access to proximal tubule cells primarily by the Organic Anion Transporter 1 (Oat1) and 3 (Oat3) in the basolateral plasma membrane. The removal process of Hg+2 ions from cells into the lumen involves an efflux process mainl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3671adafda3ad719ea425305d347567d
https://www.sciencedirect.com/science/article/abs/pii/S0378427418315030
https://www.sciencedirect.com/science/article/abs/pii/S0378427418315030
Publikováno v:
Journal of cellular biochemistry. 120(4)
Caveolin-2 (Cav-2) is expressed in a variety of cell tissue, and it has also been found in renal tissue. The expression of Cav-2 in proximal tubules is still unclear. The aim of this study was to carry out a complete evaluation of the expression patt
Autor:
María Herminia Hazelhoff, Romina Paula Bulacio, Adriana M. Torres, María Eugenia Mamprin, Anabel Brandoni, María Julia Severin
Publikováno v:
Nephrology (Carlton, Vic.). 22(8)
Aim: Furosemide is a loop diuretic. Different authors demonstrated that continuous administration of furosemide modulates the expression of organic anion transporters. This study was undertaken to simultaneously evaluate the effects of furosemide pre
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 13; Issue 8; Pages: 10523-10536
International Journal of Molecular Sciences, Vol 13, Iss 8, Pp 10523-10536 (2012)
International Journal of Molecular Sciences; Volume 13; Issue 8; Pages: 10523-10536
International Journal of Molecular Sciences, Vol 13, Iss 8, Pp 10523-10536 (2012)
The aim of this study was to determine if there are sex-related differences in the acute kidney injury induced by HgCl2 since female rats express lower levels of renal Oat1 and Oat3 (transporters involved in renal uptake of mercury) as compared with
Publikováno v:
Pharmacology. 90:66-77
Background/Aims: Calcium overload in vascular smooth muscle is a highly pathogenic event, which progresses with advancing age. Old patients are polymedicated, and several pharmacotherapeutic agents circulate in the plasma as organic anions. The organ
Cisplatin is a commonly used chemotherapeutic agent. Its main side-effect is nephrotoxicity. It was reported that the organic anion transporter 5 (Oat5) urinary excretion is elevated, implying renal perturbation, when no modifications of traditional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d56eb21e60ada5492c81e513603dad7
http://pubs.acs.org/doi/abs/10.1021/acs.chemrestox.5b00176
http://pubs.acs.org/doi/abs/10.1021/acs.chemrestox.5b00176
Publikováno v:
Archives of toxicology. 89(8)
Cisplatin is a widely used citostatic drug employed in the treatment of many solid tumors. Its principal side-effect is nephrotoxicity. The organic anion transporter 5 (Oat5) is exclusively expressed in the kidneys. The aim of this study was to evalu