Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Romina, Tripaldi"'
Autor:
Paola Simeone, Romina Tripaldi, Annika Michelsen, Thor Ueland, Rossella Liani, Sonia Ciotti, Kåre I. Birkeland, Hanne L. Gulseth, Augusto Di Castelnuovo, Francesco Cipollone, Pål Aukrust, Agostino Consoli, Bente Halvorsen, Francesca Santilli
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-12 (2022)
Abstract Background Soluble suppression of tumorigenesis-2 (sST2) and galectin (Gal)-3 are two biomarkers related to inflammation, metabolic disturbances and to myocardial fibrosis that characterize several cardiac pathological conditions. Increased
Externí odkaz:
https://doaj.org/article/c5101446b48348edacf0cd4fde89aee2
Autor:
Paola Simeone, Rossella Liani, Romina Tripaldi, Sonia Ciotti, Antonio Recchiuti, Vittorio Abbonante, Benedetta Porro, Piero Del Boccio, Augusto di Castelnuovo, Paola Lanuti, Marina Camera, Damiana Pieragostino, Melissa Lee-Sundlov, Myriam Luongo, Raffaella Auciello, Giuseppina Bologna, Maria Concetta Cufaro, Elena Tremoli, Karin M Hoffmeister, Francesco Cipollone, Alessandra Balduini, Francesca Santilli
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Cardiovascular (CV) disease prevention with low-dose aspirin can be less effective in patients with a faster recovery of platelet (PLT) cyclooxygenase (COX)-1 activity during the 24-hour dosing interval. We previously showed that incomplete suppressi
Externí odkaz:
https://doaj.org/article/07483750cdc74317a0447d692fac0177
Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer
Autor:
Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Romina Tripaldi, Giovanna Vacca, Martina Ceci, Khouloud Boujnah, Valeria Garbo, Antonino Moschella, Romina Zappacosta, Pasquale Simeone, Robert de Lange, Ulrich H. Weidle, Maria Teresa Rotelli, Arcangelo Picciariello, Raffaella Depalo, Patrizia Querzoli, Massimo Pedriali, Enzo Bianchini, Domenico Angelucci, Giuseppe Pizzicannella, Carla Di Loreto, Mauro Piantelli, Laura Antolini, Xiao-Feng Sun, Donato F. Altomare, Saverio Alberti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 898-911 (2021)
We recently reported that activation of Trop-2 through its cleavage at R87-T88 by ADAM10 underlies Trop-2–driven progression of colon cancer. However, the mechanism of action and pathological impact of Trop-2 in metastatic diffusion remain unexplor
Externí odkaz:
https://doaj.org/article/47c452d30d02427780fceca7aeda7338
Autor:
Romina Tripaldi, Paola Lanuti, Paola Giustina Simeone, Rossella Liani, Giuseppina Bologna, Sonia Ciotti, Pasquale Simeone, Augusto Di Castelnuovo, Marco Marchisio, Francesco Cipollone, Francesca Santilli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Protease proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL cholesterol clearance and has been associated with cardiovascular risk. PCSK9 inhibitors increase in vivo circulating endothelial progenitor cells (EPCs), a
Externí odkaz:
https://doaj.org/article/240420d0916c4f7da323f4207dc7fb87
Autor:
Rossella Liani, Sara La Torre, Valentina Liani, Angela Melchiorre, Danilo D’Ettorre, Romina Tripaldi, Stefano Lattanzio, Rossano Di Luzio, Mauro Coli, Carlo Velussi
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Microangiopathy compromises the structural and functional integrity of organs and tissues in patients with type II diabetes mellitus (T2DM) negatively affecting the perceived quality of life. Nitric oxide (NO) is a multifunctional signalling molecule
Externí odkaz:
https://doaj.org/article/ebc540c746224c04ad238208f143727a
Autor:
Paola G. Simeone, Francesco Vadini, Romina Tripaldi, Rossella Liani, Sonia Ciotti, Augusto Di Castelnuovo, Francesco Cipollone, Francesca Santilli
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Growing evidence indicates that cognitive decline and cardiovascular diseases (CVDs) share common vascular risk factors. Protease proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with CV disease risk and has been also i
Externí odkaz:
https://doaj.org/article/4a6b958d25ae4b9783a757721fac4065
Autor:
Rossella Liani, Paola Giustina Simeone, Romina Tripaldi, Damiano D'Ardes, Valeria Creato, Raffaele Pepe, Gianfranco Lessiani, Giuseppina Bologna, Francesco Cipollone, Marco Marchisio, Paola Lanuti, Francesca Santilli
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:1096-1106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559012e0e3283b73de06b7f38400764e
https://doi.org/10.1002/cpt.2865
https://doi.org/10.1002/cpt.2865
Autor:
Paola G. Simeone, Rossella Liani, Giuseppina Bologna, Romina Tripaldi, Augusto Di Castelnuovo, Pasquale Simeone, Damiano D'Ardes, Sebastiano Miscia, Francesco Cipollone, Marco Marchisio, Agostino Consoli, Paola Lanuti, Francesca Santilli
Publikováno v:
Nutrition, Metabolism and Cardiovascular Diseases. 33:124-132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b3b392e8a1f8a7b168f3c53d0ae2201
https://doi.org/10.1016/j.numecd.2022.09.010
https://doi.org/10.1016/j.numecd.2022.09.010
Autor:
Saverio Alberti, Laura Antolini, Nicola Tinari, Manuela Iezzi, Pietro Roversi, Massimo Pedriali, Patrizia Querzoli, Nicole Travali, Pasquale Simeone, Kristina M. Havas, Andrea Sacchetti, Ludovica Pantalone, Khouloud Boujnah, Martina Ceci, Romina Tripaldi, Rossano Lattanzio, Valeria Relli, Marco Trerotola, Emanuela Guerra
Supplementary Movie S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38280e45a49e7f825ba244207ef8ac88
https://doi.org/10.1158/1535-7163.22932210.v1
https://doi.org/10.1158/1535-7163.22932210.v1
Autor:
Saverio Alberti, Laura Antolini, Nicola Tinari, Manuela Iezzi, Pietro Roversi, Massimo Pedriali, Patrizia Querzoli, Nicole Travali, Pasquale Simeone, Kristina M. Havas, Andrea Sacchetti, Ludovica Pantalone, Khouloud Boujnah, Martina Ceci, Romina Tripaldi, Rossano Lattanzio, Valeria Relli, Marco Trerotola, Emanuela Guerra
Next-generation Trop-2–targeted therapy against advanced cancers is hampered by expression of Trop-2 in normal tissues. We discovered that Trop-2 undergoes proteolytic activation by ADAM10 in cancer cells, leading to the exposure of a previously in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643e3a47b8127482baa4b306ef223703
https://doi.org/10.1158/1535-7163.c.6653601
https://doi.org/10.1158/1535-7163.c.6653601