Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.

Autor: Deycmar S; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Roche Postdoctoral Fellowship (RPF) Program, Basel, Switzerland., Johnson BJ; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Ray K; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Schaaf GW; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Ryan DP; School of Veterinary Medicine, University of California Davis, Davis, CA, USA., Cullin C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Dozier BL; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Ferguson B; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Bimber BN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Olson JD; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Caudell DL; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Whitlow CT; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Solingapuram Sai KK; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Romero EC; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA., Villinger FJ; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA., Burgos AG; Caribbean Primate Research Center, University of Puerto Rico, Toa Baja, PR, USA., Ainsworth HC; Department of Biostatistics and Data Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Miller LD; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Hawkins GA; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Chou JW; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Gomes B; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Hettich M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Ceppi M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; iTeos Therapeutics, Translational Medicine, Gosselies, Belgium., Charo J; Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland., Cline JM; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA. jmcline@wakehealth.edu.

Publikováno v: Journal of translational medicine [J Transl Med] 2024 Mar 19; Vol. 22 (1), pp. 292. Date of Electronic Publication: 2024 Mar 19.

Comparative analysis of a novel N-butanol-prepared antigen vs thermo-resistant and sonicated antigens for human leptospirosis detection.

Autor: Blanco RM; Instituto Adolfo Lutz, Centro de Bacteriologia, Laboratório de Leptospirose, 01246-000 São Paulo, SP, Brazil.; Universidade de São Paulo, Faculdade de Medicina, Departamento de Doenças Infecciosas e Parasitárias, 01246-903 São Paulo, SP, Brazil., Lima EDS; Instituto Adolfo Lutz, Centro de Bacteriologia, Laboratório de Leptospirose, 01246-000 São Paulo, SP, Brazil., de Haro GN; Universidade de São Paulo, Faculdade de Medicina, Departamento de Doenças Infecciosas e Parasitárias, 01246-903 São Paulo, SP, Brazil., Kamikawa CM; Instituto Adolfo Lutz, Centro de Imunologia, Laboratório de Imunodiagnóstico das Micoses, 01246-000 São Paulo, SP, Brazil., Blanco RM; Associação Nova Escola 05422-001 São Paulo, SP, Brazil., Vincentini AP; Instituto Adolfo Lutz, Centro de Imunologia, Laboratório de Imunodiagnóstico das Micoses, 01246-000 São Paulo, SP, Brazil., Romero EC; Instituto Adolfo Lutz, Centro de Bacteriologia, Laboratório de Leptospirose, 01246-000 São Paulo, SP, Brazil.; Universidade de São Paulo, Faculdade de Medicina, Departamento de Doenças Infecciosas e Parasitárias, 01246-903 São Paulo, SP, Brazil.

Publikováno v: Letters in applied microbiology [Lett Appl Microbiol] 2024 Jan 02; Vol. 77 (1).

A New Recombinant Multiepitope Chimeric Protein of Leptospira interrogans Is a Promising Marker for the Serodiagnosis of Leptospirosis.

Autor: Fernandes LGV; Laboratório de Desenvolvimento de Vacinas, Instituto Butantan, Avenida Vital Brazil, 1500, Sao Paulo 05503-900, SP, Brazil., Avelar KES; Laboratório de Referência Nacional para Leptospirose, Instituto Oswaldo Cruz-Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil., Romero EC; Centro de Bacteriología, Instituto Adolfo Lutz, Sao Paulo 01246-902, SP, Brazil., Heinemann MB; Laboratório de Zoonoses Bacterianas do VPS, Faculdade de Medicina Veterinária e Zootecnia, USP, Sao Paulo 05508-270, SP, Brazil., Kirchgatter K; Laboratório de Bioquímica e Biologia Molecular, Instituto Pasteur, Sao Paulo 01027-000, SP, Brazil.; Programa de Pós Graduação em Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo 05403-000, SP, Brazil., Nascimento ALTO; Laboratório de Desenvolvimento de Vacinas, Instituto Butantan, Avenida Vital Brazil, 1500, Sao Paulo 05503-900, SP, Brazil.

Publikováno v: Tropical medicine and infectious disease [Trop Med Infect Dis] 2022 Nov 09; Vol. 7 (11). Date of Electronic Publication: 2022 Nov 09.

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components.

Autor: Rossini AD; Laboratorio Especial de Desenvolvimento de Vacinas-Centro de Biotecnologia, Instituto Butantan, Avenida Vital Brazil, 1500, 05503-900, Sao Paulo, SP, Brazil; Programa de Pós-Graduação Interunidades em Biotecnologia, ICB, USP, Avenida Prof. LineuPrestes, 1730, 05508-900, Sao Paulo, SP, Brazil., Teixeira AF; Laboratorio Especial de Desenvolvimento de Vacinas-Centro de Biotecnologia, Instituto Butantan, Avenida Vital Brazil, 1500, 05503-900, Sao Paulo, SP, Brazil., Souza Filho A; Laboratório de Zoonoses Bacterianas do VPS, Faculdade de Medicina Veterinária e Zootecnia, USP, Avenida Prof. Dr. Orlando Marques de Paiva, 87, 05508-270, Sao Paulo, SP, Brazil., Souza GO; Laboratório de Zoonoses Bacterianas do VPS, Faculdade de Medicina Veterinária e Zootecnia, USP, Avenida Prof. Dr. Orlando Marques de Paiva, 87, 05508-270, Sao Paulo, SP, Brazil., Vasconcellos SA; Laboratório de Zoonoses Bacterianas do VPS, Faculdade de Medicina Veterinária e Zootecnia, USP, Avenida Prof. Dr. Orlando Marques de Paiva, 87, 05508-270, Sao Paulo, SP, Brazil., Heinemann MB; Laboratório de Zoonoses Bacterianas do VPS, Faculdade de Medicina Veterinária e Zootecnia, USP, Avenida Prof. Dr. Orlando Marques de Paiva, 87, 05508-270, Sao Paulo, SP, Brazil., Romero EC; Centro de Bacteriologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 355, CEP 01246-902, Sao Paulo, Brazil., Nascimento ALTO; Laboratorio Especial de Desenvolvimento de Vacinas-Centro de Biotecnologia, Instituto Butantan, Avenida Vital Brazil, 1500, 05503-900, Sao Paulo, SP, Brazil. Electronic address: ana.nascimento@butantan.gov.br.

Publikováno v: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2020 Feb; Vol. 53 (1), pp. 163-175. Date of Electronic Publication: 2019 Jan 22.

Recombinant outer membrane protein Lipl41 from Leptospira interrogans robust immune responses in mice model.

Autor: Golab, Narges¹, Khaki, Pejvak² P.khaki@rvsri.ac.ir, Tebianian, Majid³, Esmaelizad, Majid⁴, Harzandi, Naser¹

Publikováno v: Iranian Journal of Microbiology. Aug2024, Vol. 16 Issue 4, p545-551. 7p.