Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Romeo J. Rosario"'
Autor:
Julio Nieves, Romeo J. Rosario, Szilard Kiss, Judith Greengard, Mehdi Gasmi, Aivan Nguyen, Ruslan Grishanin, Claire M. Gelfman
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 345-353 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Several standard-of-care therapies for the treatment of retinal disease, including aflibercept, inhibit vascular endothelial growth factor (VEGFA). The main shortcoming of these therapies is potential undertreatment due to a lack of compliance result
Autor:
Mehdi Gasmi, Ruslan Grishanin, Pallavi Sharma, Julio Nieves, Szilard Kiss, Kelly Hanna, Aivan Nguyen, Kristina Oresic Bender, Romeo J. Rosario, Claire M. Gelfman, Judith Greengard
Publikováno v:
Translational Vision Science & Technology
Purpose To evaluate the long-term safety of vascular endothelial growth factor (VEGF) suppression with sustained aflibercept expression after a single intravitreal injection (IVI) of ADVM-022, an anti-VEGF gene therapy, in non-human primates (NHPs).