Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Romeo Gabriel Mihaila"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8407-8423 (2024)
Myeloproliferative neoplasms (MPNs), encompassing disorders like polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), are characterized by clonal hematopoiesis without the Philadelphia chromosome. The JAK2 V617F mu
Externí odkaz:
https://doaj.org/article/a49f87b12aaa447683216f7cda8c9265
Autor:
Bogdan-Axente Bocea, Mihai-Dan Roman, Nicolas Catalin Ionut Ion, Sorin Radu Fleaca, Cosmin-Ioan Mohor, Darius Alexandru Popa, Romeo-Gabriel Mihaila
Publikováno v:
Healthcare, Vol 12, Iss 15, p 1511 (2024)
One of the complications after total hip arthroplasty (THA) or total knee arthroplasty (TKA) is periprosthetic joint infection (PJI). Numerous studies have been performed to explore the value of biological parameters in the early identification of in
Externí odkaz:
https://doaj.org/article/1b610e790f3945b89d580f2b37f6a69c
Autor:
Romeo Gabriel Mihaila
Publikováno v:
Biomedical Papers, Vol 167, Iss 1, Pp 1-8 (2023)
The treatment of hemophilia A has progressed amazingly in recent years. Emicizumab, a bispecific-humanized monoclonal antibody, is able to improve coagulation by bridging activated factor IX and factor X. Emicizumab is administered subcutaneously and
Externí odkaz:
https://doaj.org/article/350b903fa11c474387c8340b39181f7a
Autor:
Romeo Gabriel Mihaila
Publikováno v:
Biomedical Papers, Vol 166, Iss 2, Pp 150-154 (2022)
Adverse effects of drugs are one of the objective criteria used for choosing the most appropriate anticoagulant. It is worrying that warfarin may be involved in the progression of systemic atherosclerosis, as more and more articles suggest. Warfarin
Externí odkaz:
https://doaj.org/article/93b2522656cc48ba9535770ae23158ff
Autor:
Romeo Gabriel Mihaila, Diana Topircean
Publikováno v:
Biomedical Papers, Vol 165, Iss 3, Pp 249-257 (2021)
Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection
Externí odkaz:
https://doaj.org/article/80b275a3ae6e4e0da9613e401454cc5f
Publikováno v:
Biomedical Papers, Vol 164, Iss 3, Pp 226-235 (2020)
A better understanding of the pathogenetic mechanisms triggered by SARS-CoV-2 infection may contribute to a more effective management of patients with COVID-19. Coagulation dysfunction is a key pathogenetic element of this disease as well as a challe
Externí odkaz:
https://doaj.org/article/61c65bdc844647e7b2639d6c82ae3769
Publikováno v:
Medicine and Pharmacy Reports. 96:65-70
Background. Stroke is one of the leading causes of mortality and morbidity worldwide. Despite extensive research, to this date there is no panel of biomarkers for the prevention and prognosis of ischemic stroke and there is still much incomplete and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbdf1306099d5dd86ca0b0ace506894
https://doi.org/10.15386/mpr-2365
https://doi.org/10.15386/mpr-2365
Autor:
Romeo-Gabriel Mihaila
Publikováno v:
Biomedical Papers, Vol 161, Iss 1, Pp 50-53 (2017)
The diagnosis of essential thrombocythemia and polycythemia vera is often made during a thrombotic event which can be serious. Philadelphia-negative chronic myeloproliferative neoplasia patients have an increased thrombotic risk. This is assessed usi
Externí odkaz:
https://doaj.org/article/8bafa87092b94583aacb100ded65833b
Autor:
Romeo-Gabriel Mihaila
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 18
Background: The treatment of chronic myeloid leukemia has progressed in recent decades, becoming a model for a disease whose pathogenesis is primarily based on a genetic mutation and has led to survivals comparable to those of the general population.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9dd09e17489acbca7d27a98332efdbc
https://doi.org/10.2174/1574892818666230111115040
https://doi.org/10.2174/1574892818666230111115040
Autor:
Romeo Gabriel Mihaila
Publikováno v:
Biomedical Papers, Vol 159, Iss 4, Pp 519-526 (2015)
Background: Na+/H+ exchanger-1 (NHE-1) is involved in pH regulation and is up-regulated in different malignancies. Activation of NHE-1 is one way for allowing cells to avoid intracellular acidification and protect them against apoptosis. Inhibitors o
Externí odkaz:
https://doaj.org/article/8e3728a221644f7f83cbb912da24c5b3