Zobrazeno 1 - 4
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pro vyhledávání: '"Romell B. Gletten"'
Autor:
Kevin L. Schey, Romell B. Gletten, Carla V. T. O’Neale, Zhen Wang, Rosica S. Petrova, Paul J. Donaldson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cataract and presbyopia are the leading cause of vision loss and impaired vision, respectively, worldwide. Changes in lens biochemistry and physiology with age are responsible for vision impairment, yet the specific molecular changes that underpin su
Externí odkaz:
https://doaj.org/article/94cbc0e6f70d4a00ae9ae54f75833ed8
Publikováno v:
Molecularcellular proteomics : MCP. 22(1)
The eye lens is responsible for focusing and transmitting light to the retina. The lens does this in the absence of organelles, yet maintains transparency for at least 5 decades before onset of age-related nuclear cataract (ARNC). It is hypothesized
PURPOSETo spatially map aquaporin-5 (AQP5) expression in bovine lens, molecularly characterize cytoplasmic AQP5-containing vesicles in the outer cortex, and elucidate AQP5 membrane trafficking mechanisms.METHODSImmunofluorescence was performed on bov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e58d934e73a3c95dc619eee6127e896
https://doi.org/10.1101/2022.02.16.480789
https://doi.org/10.1101/2022.02.16.480789
Publikováno v:
Investigative Opthalmology & Visual Science. 63:5
To spatially map aquaporin-5 (AQP5) expression in the bovine lens, molecularly characterize cytoplasmic AQP5-containing vesicles in the outer cortex, and elucidate AQP5 membrane trafficking mechanisms.Immunofluorescence was performed on bovine lens c