Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses.

Autor: Altas B; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Tuffy LP; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Patrizi A; Department of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy., Dimova K; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany; Neuroproteomics Group, Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Soykan T; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Brandenburg C; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Romanowski AJ; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Whitten JR; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Robertson CD; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Khim SN; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Crutcher GW; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland., Ambrozkiewicz MC; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Yagensky O; Research Group Protein Trafficking in Synaptic Development and Function, Laboratory of Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Krueger-Burg D; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Hammer M; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Hsiao HH; Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Laskowski PR; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Dyck L; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Puche AC; Department of Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland., Sassoè-Pognetto M; Department of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy., Chua JJE; Research Group Protein Trafficking in Synaptic Development and Function, Laboratory of Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Urlaub H; Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany; Bioanalytics Group, Institute of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany., Jahn O; Neuroproteomics Group, Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany; Translational Neuroproteomics Group, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Brose N; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Poulopoulos A; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland; Department of Molecular Neurobiology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. Electronic address: apoulopoulos@som.umaryland.edu.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2024 Nov 15; Vol. 96 (10), pp. 815-828. Date of Electronic Publication: 2023 Dec 27.

Rapid modeling of an ultra-rare epilepsy variant in wild-type mice by in utero prime editing.

Autor: Robertson CD; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Davis P; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Richardson RR; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Iffland PH 2nd; Department of Neurology, and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Vieira DCO; Department of Physiology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Steyert M; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., McKeon PN; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Romanowski AJ; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Crutcher G; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Jašarević E; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.; Current affiliations: MS: Department of Neurological Surgery, University of California San Francisco; EJ: Department Computational and Systems Biology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine; TB: Department of Psychiatry, University of Colorado School of Medicine., Wolff SBE; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Mathur BN; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Crino PB; Department of Neurology, and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Bale TL; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.; Current affiliations: MS: Department of Neurological Surgery, University of California San Francisco; EJ: Department Computational and Systems Biology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine; TB: Department of Psychiatry, University of Colorado School of Medicine., Dick IE; Department of Physiology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Poulopoulos A; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 19. Date of Electronic Publication: 2023 Dec 19.

NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold.

Autor: Iffland PH; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Everett ME; Clinic for Special Children, Strasburg, PA 17579, USA., Cobb-Pitstick KM; UPMC Children's Hospital of Pittsburgh Department of Neurology, Pittsburgh, PA 15224, USA., Bowser LE; Clinic for Special Children, Strasburg, PA 17579, USA., Barnes AE; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Babus JK; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Romanowski AJ; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Baybis M; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Elziny S; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Puffenberger EG; Clinic for Special Children, Strasburg, PA 17579, USA., Gonzaga-Jauregui C; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, New York, 10591, USA., Poulopoulos A; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA., Carson VJ; Clinic for Special Children, Strasburg, PA 17579, USA., Crino PB; University of Maryland School of Medicine Departments of Neurology and Pharmacology, Baltimore, MD 21201, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2022 Nov 21; Vol. 145 (11), pp. 3872-3885.

Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity.

Autor: Altas B; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, United States., Romanowski AJ; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, United States., Bunce GW; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, United States., Poulopoulos A; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, United States.

Publikováno v: Frontiers in cellular neuroscience [Front Cell Neurosci] 2022 Apr 07; Vol. 16, pp. 853634. Date of Electronic Publication: 2022 Apr 07 (Print Publication: 2022).