Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Romano, M Carmen"'
We extend the paradigmatic and versatile TASEP (Totally Asymmetric Simple Exclusion Process) for stochastic 1d transport to allow for two different particle species, each having specific entry and exit rates. We offer a complete mean-field analysis,
Externí odkaz:
http://arxiv.org/abs/2102.02486
Publikováno v:
Phys. Rev. E 100, 050402 (2019)
Translation is a key step in the synthesis of proteins. Accordingly, cells have evolved an intricate array of control mechanisms to regulate this process. By constructing a multi-component mathematical framework for translation we uncover how transla
Externí odkaz:
http://arxiv.org/abs/1904.03064
Publikováno v:
Phys. Rev. E 97, 052139 (2018)
We develop a power series method for the nonequilibrium steady state of the inhomogeneous one-dimensional totally asymmetric simple exclusion process (TASEP) in contact with two particle reservoirs and with site-dependent hopping rates in the bulk. T
Externí odkaz:
http://arxiv.org/abs/1803.00887
Publikováno v:
Phys. Rev. Lett. 120, 128101 (2018)
One of the greatest challenges in biophysical models of translation is to identify coding sequences features that affect the rate of translation and therefore the overall protein production in the cell. We propose an analytic method to solve a transl
Externí odkaz:
http://arxiv.org/abs/1708.07678
Motor enzymes are remarkable molecular machines that use the energy derived from the hydrolysis of a nucleoside triphosphate to generate mechanical movement, achieved through different steps that constitute their kinetic cycle. These macromolecules,
Externí odkaz:
http://arxiv.org/abs/1312.1911
Publikováno v:
Phys Rev E, 87, 012705 (2013)
Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically non-static: affected by a fluctuating environment, they can undergo conformational changes. This is p
Externí odkaz:
http://arxiv.org/abs/1207.1804
Publikováno v:
J. Stat. Mech. (2012) P03002
The TASEP is a paradigmatic model from non-equilibrium statistical physics, which describes particles hopping along a lattice of discrete sites. The TASEP is applicable to a broad range of different transport systems, but does not consider the fact t
Externí odkaz:
http://arxiv.org/abs/1201.2855
Publikováno v:
Phys. Rev. E 85, 011142 (2012)
We introduce a mean-field theoretical framework to describe multiple totally asymmetric simple exclusion processes (TASEPs) with different lattice lengths, entry and exit rates, competing for a finite reservoir of particles. We present relations for
Externí odkaz:
http://arxiv.org/abs/1111.1775
We examine the dynamics of the translation stage of cellular protein production, in which ribosomes move uni-directionally along mRNA strands building an amino acid chain as they go. We describe the system using a timed event graph - a class of Petri
Externí odkaz:
http://arxiv.org/abs/1105.3580
Publikováno v:
In Biophysical Journal 2 September 2014 107(5):1176-1184