Výsledky vyhledávání - "Romane Josselin"

Akademický článek

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

Autor: Sílvia Chaves, Simonetta Resta, Federica Rinaldo, Marina Costa, Romane Josselin, Karolina Gwizdala, Luca Piemontese, Vito Capriati, A. Raquel Pereira-Santos, Sandra M. Cardoso, M. Amélia Santos

Publikováno v: Molecules, Vol 25, Iss 4, p 985 (2020)

A series of multi-target-directed ligands (MTDLs), obtained by attachment of a hydroxyphenylbenzimidazole (BIM) unit to donepezil (DNP) active mimetic moiety (benzyl-piperidine/-piperazine) was designed, synthesized, and evaluated as potential anti-A

Externí odkaz: https://doaj.org/article/59ba6ba596204f28bef514a8a69921be

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Large Hybrid Polymer/Lipid Unilamellar Vesicle (LHUV) at the nanoscale: An insight into the lipid distribution in the membrane and permeability control

Autor: Annie Brûlet, Martin Fauquignon, Elise Courtecuisse, Jean-François Le Meins, Angela Mutschler, Marc Schmutz, Romane Josselin

Publikováno v: Journal of Colloid and Interface Science
Journal of Colloid and Interface Science, Elsevier, 2021, ⟨10.1016/j.jcis.2021.06.172⟩
Journal of Colloid and Interface Science, 2021, ⟨10.1016/j.jcis.2021.06.172⟩

Membrane structuration of Large Hybrid Unilamellar Polymer/Lipid Vesicle (LHUV) is an important parameter on the optimization of their properties and thus their valuation in various fields. However, this kind of information is hardly accessible. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386c860d5a5bce69325c072e5dffdd6c
https://hal.archives-ouvertes.fr/hal-03284778/document

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Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

Autor: M. Amélia Santos, Karolina Gwizdala, Federica Rinaldo, Sílvia Chaves, Vito Capriati, Marina Costa, A. Raquel Pereira-Santos, Romane Josselin, Sandra M. Cardoso, Simonetta Resta, Luca Piemontese

Publikováno v: Molecules, Vol 25, Iss 4, p 985 (2020)
Molecules
Volume 25
Issue 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e01e0194479869baa90bad387fe4f5
https://www.mdpi.com/1420-3049/25/4/985

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Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization

Autor: Sílvia Chaves, Nóra V. May, Marina Costa, Sandra M. Cardoso, Romane Josselin, Diana Silva, M. Amélia Santos

Publikováno v: Journal of Inorganic Biochemistry. 206:111039

The intricate and multifactorial nature of Alzheimer's disease (AD) requires the development of compounds able to hit different pathophysiological targets, such as cholinergic dysfunction, deposits of amyloid beta (Aβ) peptide and metal dyshomeostas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097f62ab4891457e643e7a0c53c745c7
https://doi.org/10.1016/j.jinorgbio.2020.111039

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