Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roman V. Lenchine"'
Autor:
Lisa M. Butler, Christopher G. Proud, Zeyad D. Nassar, Yu Wu, Danielle M. Fang, Roman V. Lenchine, Jianling Xie, Jing Li, Xuemin Wang, Xin Jin
Publikováno v:
Biochemical Journal. 477:4367-4381
Emerging advances in cancer therapy have transformed the landscape towards cancer immunotherapy regimens. Recent discoveries have resulted in the development of clinical immune checkpoint inhibitors that are ‘game-changers’ for cancer immunothera
Publikováno v:
The Biochemical journal. 478(8)
Cells within solid tumours can become deprived of nutrients; in order to survive, they need to invoke mechanisms to conserve these resources. Using cancer cells in culture in the absence of key nutrients, we have explored the roles of two potential s
Autor:
Lisa M. Butler, Yu Wu, Christopher G. Proud, Roman V. Lenchine, Xin Jin, Jing Li, Xuemin Wang, Danielle M. Fang, Jianling Xie, Zeyad D. Nassar
Emerging advances in cancer therapy have transformed the landscape from conventional therapies towards cancer immunotherapy regimens. Recent discoveries have resulted in the development of clinical immune checkpoint inhibitors that are ‘game-change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f676aff2b84495763ef67ac7672a0556
https://doi.org/10.1101/2020.09.01.278655
https://doi.org/10.1101/2020.09.01.278655
Autor:
Makoto Kamei, Roman V. Lenchine, Marina Kochetkova, Jianling Xie, Kaikai Shen, Lee A. Gethings, Christopher G. Proud, Xuemin Wang, Paul J. Trim, Justin W. Kenney, Marten F. Snel, Ying Zhou
Publikováno v:
International Journal of Cancer. 142:1865-1877
Eukaryotic elongation factor 2 kinase (eEF2K) negatively regulates the elongation phase of mRNA translation and hence protein synthesis. Increasing evidence indicates that eEF2K plays an important role in the survival and migration of cancer cells an
Autor:
Stuart P. De Poi, Makoto Kamei, Ming Hong Shen, Roman V. Lenchine, Shuye Tian, Andrew C.W. Zannettino, Xuemin Wang, Sally Martin, Christopher G. Proud, Swati Irani, Ashley T. Jones, Derick Wong, Lisa M. Butler, Marten F. Snel, Kirk B. Jensen, Jianling Xie, James E. Merrett, Stephen Fitter, Andrew R. Tee, Paul J. Trim, Kaikai Shen, Jian Yang, Mengyuan Yu
Publikováno v:
Cellular and molecular life sciences : CMLS. 78(1)
eIF4E plays key roles in protein synthesis and tumorigenesis. It is phosphorylated by the kinases MNK1 and MNK2. Binding of MNKs to eIF4G enhances their ability to phosphorylate eIF4E. Here, we show that mTORC1, a key regulator of mRNA translation an
Autor:
Jianling, Xie, Kaikai, Shen, Roman V, Lenchine, Lee A, Gethings, Paul J, Trim, Marten F, Snel, Ying, Zhou, Justin W, Kenney, Makoto, Kamei, Marina, Kochetkova, Xuemin, Wang, Christopher G, Proud
Publikováno v:
International journal of cancer. 142(9)
Eukaryotic elongation factor 2 kinase (eEF2K) negatively regulates the elongation phase of mRNA translation and hence protein synthesis. Increasing evidence indicates that eEF2K plays an important role in the survival and migration of cancer cells an