Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Roman V. Deev"'
Autor:
Sergey N. Bardakov, Angelina A. Titova, Sergey S. Nikitin, Valentin Nikitins, Margarita O. Sokolova, Vadim A. Tsargush, Elena A. Yuhno, Oleg V. Vetrovoj, Pierre G. Carlier, Yana V. Sofronova, Аrtur А. Isaev, Roman V. Deev
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Dysferlinopathy is a phenotypically heterogeneous group of hereditary diseases caused by mutations in the DYSF gene. Early contractures are considered rare, and rigid spine syndrome in dysferlinopathy has been previously reported
Externí odkaz:
https://doaj.org/article/33b3ec8b75d34bd1862d731412b97b9a
Autor:
Sergey N. Bardakov, Roman V. Deev, Аrtur А. Isaev, Nikita N. Khromov‐Borisov, Evgeniy D. Kopylov, Мaria R. Savchuk, Maxim S. Pushkin, Evgeniy V. Presnyakov, Raisat M. Magomedova, Patimat G. Achmedova, Zoya R. Umakhanova, Vladimir S. Kaimonov, Elizaveta V. Musatova, Konstantin А. Blagodatskikh, Aleksandra А. Tveleneva, Yana V. Sofronova, Ivan A. Yakovlev
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract Background Dysferlinopathy has a high prevalence in relatively isolated ethnic groups where consanguineous marriages are characteristic and/or the founder effect exists. However, the frequency of endemic mutations in most isolates has not be
Externí odkaz:
https://doaj.org/article/293d70115cc14046b98306c7af3f8ccc
Autor:
Ivan A. Yakovlev, Aleksei M. Emelin, Yana S. Slesarenko, Igor S. Limaev, Iuliia A. Vetrova, Liliya D. Belikova, Ekaterina N. Grafskaia, Pavel A. Bobrovsky, Mikhail V. Pokrovsky, Elena V. Kuzubova, Vladimir M. Pokrovsky, Pyotr A. Lebedev, Sergei N. Bardakov, Artur A. Isaev, Roman V. Deev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13551 (2023)
Dysferlinopathy treatment is an active area of investigation. Gene therapy is one potential approach. We studied muscle regeneration and inflammatory response after injection of an AAV-9 with a codon-optimized DYSF gene. A dual-vector system AAV.DYSF
Externí odkaz:
https://doaj.org/article/67ee5682befc4594b6f8fa72e658939b
Autor:
Eugene N. Kozlov, Roman V. Deev, Elena V. Tokmatcheva, Anna Tvorogova, Zaur M. Kachaev, Rudolf A. Gilmutdinov, Mariya Zhukova, Elena V. Savvateeva-Popova, Paul Schedl, Yulii V. Shidlovskii
Publikováno v:
Cells, Vol 12, Iss 13, p 1717 (2023)
Intracellular trafficking plays a critical role in the functioning of highly polarized cells, such as neurons. Transport of mRNAs, proteins, and other molecules to synaptic terminals maintains contact between neurons and ensures the transmission of n
Externí odkaz:
https://doaj.org/article/113e321edc534cb68cd76ede37f140a9
Autor:
Eugene N. Kozlov, Elena V. Tokmatcheva, Anastasia M. Khrustaleva, Eugene S. Grebenshchikov, Roman V. Deev, Rudolf A. Gilmutdinov, Lyubov A. Lebedeva, Mariya Zhukova, Elena V. Savvateeva-Popova, Paul Schedl, Yulii V. Shidlovskii
Publikováno v:
Cells, Vol 12, Iss 2, p 318 (2023)
Activation of local translation in neurites in response to stimulation is an important step in the formation of long-term memory (LTM). CPEB proteins are a family of translation factors involved in LTM formation. The Drosophila CPEB protein Orb2 play
Externí odkaz:
https://doaj.org/article/8c81c77751544639a294a99f6877d87b
Autor:
Igor L. Plaksa, Nina D. Mzhavanadze, Roman E. Kalinin, Igor A. Suchkov, Michail U. Bakunov, Vyacheslav T. Krivichin, Sergey A. Matveev, Artur A. Isaev, Roman V. Deev
Publikováno v:
Сахарный диабет, Vol 22, Iss 6, Pp 559-567 (2019)
BACKGROUND: The syndrome of diabetic foot remains the main cause of non-traumatic amputation of the lower extremity in the world. Even with the provision of comprehensive medical care in the conditions of a specialized center, 10-15% of patients do n
Externí odkaz:
https://doaj.org/article/10ea3aa93c384104a861a4d47aaf033e
Autor:
Anna V. Vakhrusheva, Aleksandr V. Kudriavtsev, Nickolay A. Kryuchkov, Roman V. Deev, Maria E. Frolova, Konstantin A. Blagodatskikh, Milana Djonovic, Andrey A. Nedorubov, Elena Odintsova, Aleksandr V. Ivanov, Ekaterina A. Romanovskaya-Romanko, Marina A. Stukova, Artur A. Isaev, Igor V. Krasilnikov
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1290 (2022)
Public health threat coming from a rapidly developing COVID-19 pandemic calls for developing safe and effective vaccines with innovative designs. This paper presents preclinical trial results of “Betuvax-CoV-2”, a vaccine developed as a subunit v
Externí odkaz:
https://doaj.org/article/851cfce278b44cd98b921243d6ba8a58
Autor:
Piers Wilkinson, Ilya Y. Bozo, Thomas Braxton, Peter Just, Elena Jones, Roman V. Deev, Peter V. Giannoudis, Georg A. Feichtinger
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Bone defects and improper healing of fractures are an increasing public health burden, and there is an unmet clinical need in their successful repair. Gene therapy has been proposed as a possible approach to improve or augment bone healing with the p
Externí odkaz:
https://doaj.org/article/0f6c1889b40a413ba8a5e05bc1502bd9
Autor:
Ilia Y. Bozo, Alexey Y. Drobyshev, Nikolay A. Redko, Vladimir S. Komlev, Artur A. Isaev, Roman V. Deev
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Bone grafting and reconstruction are still challenging in clinical practice because of the limitations of bone autografts and the drawbacks of currently approved bone substitutes. We thus developed a gene-activated bone substitute based on octacalciu
Externí odkaz:
https://doaj.org/article/1e24cdec711945b98c3ba9c048f76a44
Publikováno v:
HERALD of North-Western State Medical University named after I.I. Mechnikov. 14:43-52
BACKGROUND: According to clinical and statistical observations, there is the high prevalence of gingival recession in children and adults. Currently, the methods of treating gingival recession are considered as corrective surgical measures. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a1a43ddfab4df47c980567edab0b28
https://doi.org/10.17816/mechnikov112258
https://doi.org/10.17816/mechnikov112258