Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roman U. Goz"'
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://doaj.org/article/0dab2a5c70df4751af18ae27826dc208
Autor:
Roman U. Goz, Bryan M. Hooks
In mammalian cortex, feedforward excitatory connections recruit feedforward inhibition. This is often carried by parvalbumin (PV+) interneurons, which may densely connect to local pyramidal (Pyr) neurons. Whether this inhibition affects all local exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf869bb0613b29df3af75508c8829c78
https://doi.org/10.1101/2022.09.12.507457
https://doi.org/10.1101/2022.09.12.507457
Autor:
Bryan M. Hooks, Sandra U Okoro, Madhumita Harish, Catherine F. Ruff, Charles R. Gerfen, Brigdet W. Njeri, Sarah E. Ross, Roman U Goz
Publikováno v:
J Neurosci
Intracortical inhibition in motor cortex (M1) regulates movement and motor learning. If cortical and thalamic inputs target different inhibitory cell types in different layers, then these afferents may play different roles in regulating M1 output. Us
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Pärn, A, Olsen, D, Tuvikene, J, Kaas, M, Borisova, E, Bilgin, M, Elhauge, M, Vilstrup, J, Madsen, P, Ambrozkiewicz, M C, Goz, R U, Timmusk, T, Tarabykin, V, Gustafsen, C & Glerup, S 2022, ' PCSK9 deficiency alters brain lipid composition without affecting brain development and function ', Frontiers in Molecular Neuroscience, vol. 15, pp. 1084633 . https://doi.org/10.3389/fnmol.2022.1084633
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3581b02e08f0a7fb6ef1652b1549c718
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
BACKGROUNDFrequentde-novosomatic mutations in major components (PI3KCA, AKT3, TSC1, TSC2, mTOR, BRAF) of molecular pathways crucial for cell differentiation, proliferation, growth and migration (mTOR, MAPK) has been previously implicated in malformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7946f385439b961454141ce9728799d