Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Roman Tůma"'
Helicase domain of nonstructural protein 3 (NS3H) unwinds double-stranded RNA replication intermediate during flavivirus life cycle in ATP-dependent manner. While the helicases mechanism of Dengue and Zika viruses has been extensively studied, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58291c563b27703a9ee628da2edf294
https://doi.org/10.1101/2022.03.15.484399
https://doi.org/10.1101/2022.03.15.484399
Direct Synthesis and Characterization of Hydrophilic Cu-Deficient Copper Indium Sulfide Quantum Dots
Autor:
Amanda Richardson, Jan Alster, Petro Khoroshyy, Jakub Psencik, Jan Valenta, Roman Tuma, Kevin Critchley
Publikováno v:
ACS Omega, Vol 9, Iss 15, Pp 17114-17124 (2024)
Externí odkaz:
https://doaj.org/article/e134c750078547848ef28bfe904b2437
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C853-C853
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::389cef5ec16259ab814b729944505e2f
https://doi.org/10.1107/s0108767321088450
https://doi.org/10.1107/s0108767321088450
Autor:
Helena Zábranská, Roman Tůma, Iva Pichová, Tomáš Ruml, Richard Hrabal, Ivan Kluh, Aleš Svatoš
Publikováno v:
Journal of Molecular Biology. 365:1493-1504
Retroviral proteases are translated as a part of Gag-related polyproteins, and are released and activated during particle release. Mason-Pfizer monkey virus (M-PMV) Gag polyproteins assemble into immature capsids within the cytoplasm of the host cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3709c9f83ecd3b4fd25b3184ec0f39b
https://doi.org/10.1016/j.jmb.2006.11.005
https://doi.org/10.1016/j.jmb.2006.11.005
Autor:
Matthew G. Iadanza, Bob Schiffrin, Paul White, Matthew A. Watson, Jim E. Horne, Anna J. Higgins, Antonio N. Calabrese, David J. Brockwell, Roman Tuma, Antreas C. Kalli, Sheena E. Radford, Neil A. Ranson
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
With cryo-EM, single-molecule FRET and MD simulations, Iadanza et al. characterise the membrane protein insertase complex BAM in lipid bilayer nanodiscs. They show that the β-barrel domain of BamA is in a ‘lateral open’ conformation, and that BA
Externí odkaz:
https://doaj.org/article/cc183779d41f4d5aabd191eaa4c934aa
Autor:
Antonio N. Calabrese, Bob Schiffrin, Matthew Watson, Theodoros K. Karamanos, Martin Walko, Julia R. Humes, Jim E. Horne, Paul White, Andrew J. Wilson, Antreas C. Kalli, Roman Tuma, Alison E. Ashcroft, David J. Brockwell, Sheena E. Radford
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The chaperone SurA is involved in outer membrane protein (OMP) biogenesis in Gram-negative bacteria, but its mechanism of action is not fully understood. Combining mass spectrometric, biophysical and computational approaches, the authors here show ho
Externí odkaz:
https://doaj.org/article/2047c9564bc341c98f0fa558c55a100a
Artificial Differences in Clostridium difficile Infection Rates Associated with Disparity in Testing
Autor:
Mini Kamboj, Jennifer Brite, Anoshe Aslam, Jessica Kennington, N. Esther Babady, David Calfee, Yoko Furuya, Donald Chen, Michael Augenbraun, Belinda Ostrowsky, Gopi Patel, Monica Mircescu, Vivek Kak, Roman Tuma, Teresa A. Karre, Deborah A. Fry, Yola P. Duhaney, Amber Moyer, Denise Mitchell, Sherry Cantu, Candace Hsieh, Nancy Warren, Stacy Martin, Jill Willson, Jeanne Dickman, Julie Knight, Kim Delahanty, Annemarie Flood, Jennifer Harrington, Deborah Korenstein, Janet Eagan, Kent Sepkowitz
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 3, Pp 584-587 (2018)
In 2015, Clostridium difficile testing rates among 30 US community, multispecialty, and cancer hospitals were 14.0, 16.3, and 33.9/1,000 patient-days, respectively. Pooled hospital onset rates were 0.56, 0.84, and 1.57/1,000 patient-days, respectivel
Externí odkaz:
https://doaj.org/article/44d90c5f72814f668d040474ed21cd09
Autor:
Tomas Fessl, Daniel Watkins, Peter Oatley, William John Allen, Robin Adam Corey, Jim Horne, Steve A Baldwin, Sheena E Radford, Ian Collinson, Roman Tuma
Publikováno v:
eLife, Vol 7 (2018)
Protein translocation across cell membranes is a ubiquitous process required for protein secretion and membrane protein insertion. In bacteria, this is mostly mediated by the conserved SecYEG complex, driven through rounds of ATP hydrolysis by the cy
Externí odkaz:
https://doaj.org/article/f35fb7d26f204ee7a792ed18827c7779
Autor:
William John Allen, Robin Adam Corey, Peter Oatley, Richard Barry Sessions, Steve A Baldwin, Sheena E Radford, Roman Tuma, Ian Collinson
Publikováno v:
eLife, Vol 5 (2016)
The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However,
Externí odkaz:
https://doaj.org/article/59d7786eb5d341c08ab44400f000bb12