Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Roman S Kirsanov"'
Autor:
Iliuza R Iaubasarova, Ljudmila S Khailova, Alexander M Firsov, Vera G Grivennikova, Roman S Kirsanov, Galina A Korshunova, Elena A Kotova, Yuri N Antonenko
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244499 (2020)
The synthesis of a mitochondria-targeted derivative of the classical mitochondrial uncoupler carbonyl cyanide-m-chlorophenylhydrazone (CCCP) by alkoxy substitution of CCCP with n-decyl(triphenyl)phosphonium cation yielded mitoCCCP, which was able to
Externí odkaz:
https://doaj.org/article/06c2b5d970a34d868e4289644bb2430a
Autor:
Roman S. Kirsanov, Ljudmila S. Khailova, Tatyana I. Rokitskaya, Konstantin G. Lyamzaev, Alisa A. Panteleeva, Pavel A. Nazarov, Alexander M. Firsov, Iliuza R. Iaubasarova, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11551-11561 (2024)
Externí odkaz:
https://doaj.org/article/a4be645a79fa4de490a45a3780dca471
Autor:
Svyatoslav S. Sokolov, Ekaterina A. Smirnova, Olga V. Markova, Natalya A. Kireeva, Roman S. Kirsanov, Liudmila S. Khailova, Dmitry A. Knorre, Fedor F. Severin
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1345 (2020)
Chemicals inducing a mild decrease in the ATP/ADP ratio are considered as caloric restriction mimetics as well as treatments against obesity. Screening for such chemicals in animal model systems requires a lot of time and labor. Here, we present a sy
Externí odkaz:
https://doaj.org/article/2521315c69294ff69757321505e036f1
Autor:
Pavel A. Nazarov, Roman S. Kirsanov, Stepan S. Denisov, Ljudmila S. Khailova, Marina V. Karakozova, Konstantin G. Lyamzaev, Galina A. Korshunova, Konstantin A. Lukyanov, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 309 (2020)
Appending a lipophylic alkyl chain by ester bond to fluorescein has been previously shown to convert this popular dye into an effective protonophoric uncoupler of oxidative phosphorylation in mitochondria, exhibiting neuro- and nephroprotective effec
Externí odkaz:
https://doaj.org/article/4b11e352d7ed4190a4089a20701f1c43
Autor:
Vladimir S. Krasnov, Roman S. Kirsanov, Ljudmila S. Khailova, Lyudmila B. Popova, Konstantin G. Lyamzaev, Alexander M. Firsov, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Archives of biochemistry and biophysics. 728
An impressive body of evidence has been accumulated now on sound beneficial effects of mitochondrial uncouplers in struggling with the most dangerous pathologies such as cancer, infective diseases, neurodegeneration and obesity. To increase their eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747f9aa42dea37dcf7b4d0011619acd2
https://pubmed.ncbi.nlm.nih.gov/35878680
https://pubmed.ncbi.nlm.nih.gov/35878680
Autor:
Roman S. Kirsanov, Ljudmila S. Khailova, Tatyana I. Rokitskaya, Iliuza R. Iaubasarova, Pavel A. Nazarov, Alisa A. Panteleeva, Konstantin G. Lyamzaev, Lyudmila B. Popova, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Bioelectrochemistry. 150:108369
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d743b16b51a690b5e743b201b8e675
https://doi.org/10.1016/j.bioelechem.2023.108369
https://doi.org/10.1016/j.bioelechem.2023.108369
Autor:
Vladimir S. Krasnov, Roman S. Kirsanov, Ljudmila S. Khailova, Alexander M. Firsov, Pavel A. Nazarov, Vadim N. Tashlitsky, Galina A. Korshunova, Elena A. Kotova, Yuri N. Antonenko
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 145
A great variety of coumarin-related compounds, both natural and synthetic, being often brightly fluorescent, have shown themselves beneficial in medicine for both therapeutic and imaging purposes. Here, in search for effective uncouplers of oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8342e7a05b696b8ec77969f3b5bb232
https://pubmed.ncbi.nlm.nih.gov/35131667
https://pubmed.ncbi.nlm.nih.gov/35131667
Autor:
Roman S. Kirsanov, Lyudmila S. Khailova, I.R. Iaubasarova, Egor Y. Plotnikov, T. I. Danilina, Dmitry B. Zorov, Tatiana I. Rokitskaya, Galina A. Korshunova, Pavel A. Nazarov, Stepan S. Denisov, Elena A. Kotova, Denis N. Silachev, Yury N. Antonenko
Publikováno v:
Biochemistry-Moscow, 85(12-13), 1578-1590. Maik Nauka-Interperiodica Publishing
Appending lipophilic cations to small molecules has been widely used to produce mitochondria-targeted compounds with specific activities. In this work, we obtained a series of derivatives of the well-known fluorescent dye 7-nitrobenzo-2-oxa-1,3-diazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adebba850e0ec1fd9c450ed7bba551fb
https://pubmed.ncbi.nlm.nih.gov/33705296
https://pubmed.ncbi.nlm.nih.gov/33705296
Autor:
Dmitry A. Knorre, Liudmila S Khailova, Natalya A Kireeva, Ekaterina A. Smirnova, Svyatoslav S. Sokolov, Olga V. Markova, Roman S. Kirsanov, Fedor F. Severin
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 1345, p 1345 (2020)
Volume 10
Issue 9
Biomolecules, Vol 10, Iss 1345, p 1345 (2020)
Volume 10
Issue 9
Chemicals inducing a mild decrease in the ATP/ADP ratio are considered as caloric restriction mimetics as well as treatments against obesity. Screening for such chemicals in animal model systems requires a lot of time and labor. Here, we present a sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97dad2d4fce1dc76ef444b542855f17c
http://europepmc.org/articles/PMC7563754
http://europepmc.org/articles/PMC7563754
Autor:
Vadim N. Tashlitsky, Elena A. Kotova, Yuri N. Antonenko, Victor B. Luzhkov, Tatyana I. Rokitskaya, Galina A. Korshunova, Ekaterina V. Aleksandrova, Roman S. Kirsanov
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1863(1)
To clarify the contribution of charge delocalization in a lipophilic ion to the efficacy of its permeation through a lipid membrane, we compared the behavior of alkyl derivatives of triphenylphosphonium, tricyclohexylphosphonium and trihexylphosphoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5db5d4911d81f29cf1984c519e65cc
https://pubmed.ncbi.nlm.nih.gov/33002452
https://pubmed.ncbi.nlm.nih.gov/33002452