Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Roman Pohorecki"'
Autor:
Roman Pohorecki, Gary E. Hill
Publikováno v:
Open Journal of Anesthesiology. :338-344
This article discusses risk and uncertainty, both stochastic and epistemic, as it applies to anesthesia. It shows the difficulty in quantifying risk of individual case and the somewhat arbitrary and even incorrect and naive assignment of risk in indi
Publikováno v:
Anesthesia & Analgesia. 83:696-700
Pulmonary neutrophil entrapment and resultant oxidative injury is thought to be the primary mechanism of cardiopulmonary bypass (CPB) induced lung injury. Interleukin-8 (IL-8), a potent neutrophil chemoattractant induced by cytokines, including tumor
Publikováno v:
Liver Transplantation and Surgery. 1:220-224
Both cold and warm ischemia occur during liver transplantation. Hypothermia and Wisconsin solution preserve adenine nucleotide energy status, which is crucial to hepatic function and viability. The volatile anesthetic isoflurane has been shown to pre
Publikováno v:
Anesthesia & Analgesia. 81:170-172
Publikováno v:
Annals of the New York Academy of Sciences. 625:818-820
Publikováno v:
The Annals of thoracic surgery. 65(1)
Cardiopulmonary bypass (CPB) is characterized by the systemic release of proinflammatory cytokines, such as tumor necrosis factor-alpha and the interleukins 1 and 6, as well as endogenous antiinflammatory cytokines, including interleukin-10 (IL-10).
Publikováno v:
Anesthesia and analgesia. 82(6)
The hypothesis that general anesthetics protect energy reserves by decreasing energy demand is widely accepted but poorly substantiated. Isoflurane at clinical doses preserved adenosine triphosphate (ATP) levels in anoxic isolated hepatocytes. Specif
Publikováno v:
Brain research. 528(1)
Excessive Ca 2+ influx through NMDA receptor-coupled channels has been linked to neuronal cell death. Using an in vitro model of transient brain ischemia, we investigated possible protective effects of NMDA receptor antagonists ketamine or MK-801 and
Publikováno v:
Anesthesiology. 89:385A
Publikováno v:
Anesthesia & Analgesia. 77:38
We investigated how the protection of energy status by isoflurane in isolated hepatocytes varied with isoflurane dose, duration of anoxia, and reoxygenation. Hepatocytes were isolated from fed rats and incubated in Krebs buffer under O2/CO2 or N2/CO2