Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Roman Pichler"'
Autor:
Valentina Marchesin, Albert Pérez-Martí, Gwenn Le Meur, Roman Pichler, Kelli Grand, Enriko D. Klootwijk, Anne Kesselheim, Robert Kleta, Soeren Lienkamp, Matias Simons
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4407-4421.e5 (2019)
Summary: HNF4A is a nuclear hormone receptor that binds DNA as an obligate homodimer. While all known human heterozygous mutations are associated with the autosomal-dominant diabetes form MODY1, one particular mutation (p.R85W) in the DNA-binding dom
Externí odkaz:
https://doaj.org/article/f2fbf2aa5c0f464d94cfbc91535c9623
Autor:
Simon Lagies, Roman Pichler, Georg Vladimirov, Jana Gawron, Fabian Bäzner, Annabell Schreiner, Dajana Kadena, Dietmar A. Plattner, Soeren S. Lienkamp, Bernd Kammerer
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10111 (2021)
Vancomycin is a glycopeptide antibiotic used against multi-drug resistant gram-positive bacteria such as Staphylococcus aureus (MRSA). Although invaluable against resistant bacteria, vancomycin harbors adverse drug reactions including cytopenia, otot
Externí odkaz:
https://doaj.org/article/fb585441398f43efb98e717c7f7119b3
Autor:
Simon Lagies, Roman Pichler, Tillmann Bork, Michael M. Kaminski, Kevin Troendle, Stefan Zimmermann, Tobias B. Huber, Gerd Walz, Soeren S. Lienkamp, Bernd Kammerer
Publikováno v:
Cells, Vol 8, Iss 10, p 1141 (2019)
Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminur
Externí odkaz:
https://doaj.org/article/a91776ebcf7c4988a28d0b99388a9ade
Autor:
Roman Pichler, Ludovica Rizzo, Kevin Tröndle, Michaela Bühler, Hanna Brucker, Anna-Lena Müller, Kelli Grand, Silvia Farè, Amandine Viau, Michael M. Kaminski, E. Wolfgang Kuehn, Fritz Koch, Stefan Zimmermann, Peter Koltay, Soeren S. Lienkamp
Publikováno v:
Biomaterials. 291
Renal tubular cells frequently lose differentiation markers and physiological properties when propagated in conventional cell culture conditions. Embedding cells in 3D microenvironments or controlling their 3D assembly by bioprinting can enhance thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87e067270303ffef91c830f350a5f4b
https://pubmed.ncbi.nlm.nih.gov/36403325
https://pubmed.ncbi.nlm.nih.gov/36403325
Autor:
Kevin Troendle, Stefan Zimmermann, Fritz Koch, Roman Pichler, Peter Koltay, Roland Zengerle, Ahmad Itani, Ludovica Rizzo, Soeren S. Lienkamp
Publikováno v:
Biofabrication
Scalable fabrication concepts of 3D kidney tissue models are required to enable their application in pharmaceutical high-throughput screenings. Yet the reconstruction of complex tissue structures remains technologically challenging. We present a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefa074ca808a3e409d43b69049e86fa
Autor:
Roman Pichler
Ein erfolgreiches Produkt zu entwickeln ist keine Frage des Glücks, sondern der richtigen strategischen Entscheidungen. Dieses Buch unterstützt Sie hierbei. Es enthält hilfreiche Konzepte, Techniken und Tools und erklärt, wie Sie eine inspirier
Autor:
Albert Pérez-Martí, Valentina Marchesin, Anne Kesselheim, Soeren S. Lienkamp, Robert Kleta, Matias Simons, Kelli Grand, Roman Pichler, Gwenn Le Meur, Enriko Klootwijk
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2019, 29, pp.4407-4421.e5. ⟨10.1016/j.celrep.2019.11.066⟩
Cell Reports, Vol 29, Iss 13, Pp 4407-4421.e5 (2019)
Cell Reports, Elsevier Inc, 2019, 29, pp.4407-4421.e5. ⟨10.1016/j.celrep.2019.11.066⟩
Cell Reports, Vol 29, Iss 13, Pp 4407-4421.e5 (2019)
Summary HNF4A is a nuclear hormone receptor that binds DNA as an obligate homodimer. While all known human heterozygous mutations are associated with the autosomal-dominant diabetes form MODY1, one particular mutation (p.R85W) in the DNA-binding doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a380e83a6337800d9b5f5c7d9b604c
https://hal.archives-ouvertes.fr/hal-03489229
https://hal.archives-ouvertes.fr/hal-03489229
Autor:
Roman Pichler
Pflichtlektüre für jeden angehenden und erfahrenen Produktmanager Grundlagen, spezifische Techniken und hilfreiche Praktiken Sechs Herausforderungen für Product Leadership Das Treppenstufenmodell zur Verhaltensänderung Storytelling aus dem Leben
Autor:
Michael M. Kaminski, Gerd Walz, Simon Lagies, Manuel Schlimpert, Bernd Kammerer, Roman Pichler, Soeren S. Lienkamp
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426daeb01fa279844f5d4fd7df2c459b
http://edoc.mdc-berlin.de/18758/1/18758oa.pdf
http://edoc.mdc-berlin.de/18758/1/18758oa.pdf
Autor:
Simon Lagies, Bernd Kammerer, Soeren S. Lienkamp, Michael M. Kaminski, Manuel Schlimpert, Gerd Walz, Roman Pichler
Publikováno v:
Proceedings of The 2nd International Electronic Conference on Metabolomics.
Forced expression of four transcription factors are sufficient to reprogram mouse embryonic fibroblasts (MEFs) directly to induced renal tubular epithelial cells (iRECs). These cells have been characterized as tubule cells by transcriptomic, morpholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619875b6bee7aa92cef68a8904e8307c
https://doi.org/10.3390/iecm-2-04991
https://doi.org/10.3390/iecm-2-04991