Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Roman Muff"'
Autor:
Alekhya Mazumdar, Joaquin Urdinez, Aleksandar Boro, Matthias J. E. Arlt, Fabian E. Egli, Barbara Niederöst, Patrick K. Jaeger, Greta Moschini, Roman Muff, Bruno Fuchs, Jess G. Snedeker, Ana Gvozdenovic
Publikováno v:
Cancers, Vol 12, Iss 11, p 3457 (2020)
The pre-metastatic niche (PMN) is a tumor-driven microenvironment in distant organs that can foster and support the survival and growth of disseminated tumor cells. This facilitates the establishment of secondary lesions that eventually form overt me
Externí odkaz:
https://doaj.org/article/a59317cdb9cf46819a86ab5d65cb9a9a
Autor:
Alekhya Mazumdar, Joaquin Urdinez, Aleksandar Boro, Jessica Migliavacca, Matthias J.E. Arlt, Roman Muff, Bruno Fuchs, Jess Gerrit Snedeker, Ana Gvozdenovic
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5451 (2020)
Tumor-secreted extracellular vesicles (EVs) have been identified as mediators of cancer–host intercellular communication and shown to support pre-metastatic niche formation by modulating stromal cells at future metastatic sites. While osteosarcoma,
Externí odkaz:
https://doaj.org/article/a0eea1f473bc4d8f81475afd1d31698b
Autor:
Roman Muff, Prisni Rath, Ram Mohan Ram Kumar, Knut Husmann, Walter Born, Michael Baudis, Bruno Fuchs
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125611 (2015)
Osteosarcoma is a rare but highly malignant cancer of the bone. As a consequence, the number of established cell lines used for experimental in vitro and in vivo osteosarcoma research is limited and the value of these cell lines relies on their stabi
Externí odkaz:
https://doaj.org/article/7c889e8ce0384481a5c4edf8762242a6
Autor:
Matthias J. E. Arlt, Ingo J. Banke, Josefine Bertz, Ram Mohan Ram Kumar, Roman Muff, Walter Born, Bruno Fuchs
Publikováno v:
Sarcoma, Vol 2013 (2013)
Metastasis is the major cause of death of osteosarcoma patients and its diagnosis remains difficult. In preclinical studies, however, forced expression of reporter genes in osteosarcoma cells has remarkably improved the detection of micrometastases a
Externí odkaz:
https://doaj.org/article/0dc6adbe00ab4292bdcfb66563759988
Autor:
Ana Gvozdenovic, Matthias J E Arlt, Carmen Campanile, Patrick Brennecke, Knut Husmann, Walter Born, Roman Muff, Bruno Fuchs
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60329 (2013)
Osteosarcoma (OS) is the most frequent primary malignant bone cancer in children and adolescents with a high propensity for lung metastasis. Therefore, it is of great importance to identify molecular markers leading to increased metastatic potential
Externí odkaz:
https://doaj.org/article/2d1642759ffe43d095769fde8eab1d58
Autor:
Patrick Brennecke, Matthias J E Arlt, Roman Muff, Carmen Campanile, Ana Gvozdenovic, Knut Husmann, Nathalie Holzwarth, Elisabetta Cameroni, Felix Ehrensperger, Marcus Thelen, Walter Born, Bruno Fuchs
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74045 (2013)
More effective treatment of metastasizing osteosarcoma with a current mean 5-year survival rate of less than 20% requires more detailed knowledge on mechanisms and key regulatory molecules of the complex metastatic process. CXCR4, the receptor of the
Externí odkaz:
https://doaj.org/article/2ed866bc26c84ca29cb72225614364d9
Publikováno v:
Sarcoma, Vol 2012 (2012)
Osteosarcoma (OS) is a rare bone neoplasm that affects mainly adolescents. It is associated with poor prognosis in case of metastases formation. The search for metastasis predicting markers is therefore imperative to optimize treatment strategies for
Externí odkaz:
https://doaj.org/article/b9b6667d54c24d27946d5870d344c3bf
Autor:
Aleksandar Boro, Barbara Niederöst, Matthias J.E. Arlt, Alekhya Mazumdar, Roman Muff, Bruno Fuchs, Greta Moschini, Fabian E. Egli, Ana Gvozdenovic, Patrick K. Jaeger, Jess G. Snedeker, Joaquin Urdinez
Publikováno v:
Cancers
Volume 12
Issue 11
Cancers, 12 (11)
Cancers, Vol 12, Iss 3457, p 3457 (2020)
Volume 12
Issue 11
Cancers, 12 (11)
Cancers, Vol 12, Iss 3457, p 3457 (2020)
The pre-metastatic niche (PMN) is a tumor-driven microenvironment in distant organs that can foster and support the survival and growth of disseminated tumor cells. This facilitates the establishment of secondary lesions that eventually form overt me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d767ee82ef9dd5d49bd982f6bd61a2f
Autor:
Aleksandar Boro, Beata Bode-Lesniewska, Joaquin Urdinez, Alekhya Mazumdar, Sander M. Botter, Jess G. Snedeker, Roman Muff, Bruno Fuchs, Ana Gvozdenovic, Matthias J.E. Arlt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59741c0745110704001991ba8da4e679
https://doi.org/10.1002/jbmr.3976/v2/response1
https://doi.org/10.1002/jbmr.3976/v2/response1
Autor:
Philomina Selvam, Franziska Seeli-Maduz, Bruno Fuchs, Roman Muff, Sander M. Botter, Joelle Tchinda, Knut Husmann
Publikováno v:
Laboratory Investigation. 96:752-762
Human sarcomas comprise a heterogeneous group of rare tumors that affect soft tissues and bone. Due to the scarcity and heterogeneity of these diseases, patient-derived cells that can be used for preclinical research are limited. In this study, we in