Výsledky vyhledávání - "Roman Mizera"

ROS Scavenger Decreases Basal Perfusion Pressure, Vasoconstriction and NO Synthase Activity in Pulmonary Circulation During Pulmonary Microembolism

Autor: Roman Mizera, Jan Herget, Daniel Hodyc

Publikováno v: Physiological Research. :683-688

Two mechanisms contribute in the development of pulmonary hypertension in pulmonary embolism (PE) – obstruction of pulmonary blood vessels and vasoconstriction. We hypothesize that hypoxia, increased shear stress and/or activation of gathered leuko

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffdec6e16aa6ad0316689cb924ca07d9
https://doi.org/10.33549/physiolres.932906

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Role of Kv7 channels in responses of the pulmonary circulation to hypoxia

Autor: Alison M. Gurney, Roman Mizera, Vojtech Sedivy, Youssef Ghaly, Marie Zaloudikova, Jana Novotná, Jan Herget, Shreena Joshi, Sean Brennan

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology

Hypoxic pulmonary vasoconstriction (HPV) is a beneficial mechanism that diverts blood from hypoxic alveoli to better ventilated areas of the lung, but breathing hypoxic air causes the pulmonary circulation to become hypertensive. Responses to airway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989ccd24974a88e5a777ac043e6152b0
https://doi.org/10.1152/ajplung.00362.2013

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Increased NO‐synthase activity and beneficial effect of PDE‐5 inhibition by sildenafil in pulmonary hypertension caused by pulmonary embolism (LB646)

Autor: Roman Mizera, Daniel Hodyc, Jan Herget

Publikováno v: The FASEB Journal. 28

Background Two mechanisms that contribute to pulmonary hypertension after acute pulmonary embolism (PE) are vascular obstruction and vasoconstriction. Vasoconstriction is influenced by NO release. We focused on NO synthase activity, production of NO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b0997ae0d22edb25fc7189d1d24b898
https://doi.org/10.1096/fasebj.28.1_supplement.lb646

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Reactive Oxygen Species Scavenger, Tempol, Decreases Vasoconstriction after Acute Pulmonary Embolism

Autor: Roman Mizera, Vaclav Hampl, Daniel Hodyc, Jan Herget

Publikováno v: The FASEB Journal. 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e94407043ed2098078b64eba10c4d76
https://doi.org/10.1096/fasebj.26.1_supplement.lb627

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