Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Roman M. Kassa"'
Publikováno v:
European Journal of Histochemistry, Vol 62, Iss 2 (2018)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by motoneuron death. Several cellular pathways have been described to be involved in ALS pathogenesis; however, the involvement of presynaptic stripping and
Externí odkaz:
https://doaj.org/article/37f1b8b8f4a043589904a51390885481
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 1, Pp 121-133 (2007)
Involvement of P2X1 and P2X2 purinergic receptors in motoneuron response to injury was investigated with Western blotting and immunohistochemistry and correlated with motoneuron loss, Bcl-2 expression, nitric oxide synthase induction and glial activa
Externí odkaz:
https://doaj.org/article/9fa08d8df82946cfadb972176d8d2904
Autor:
B. Mark Keegan, Roman M. Kassa
Publikováno v:
Mayo Clinic Cases in Neuroimmunology
A 78-year-old man with no pertinent medical history sought care for an 18-month history of progressive right lower extremity weakness, gait impairment, and falls. On neurologic examination, he had a hemiparetic gait. He had normal higher cognitive fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cddc6130fe272812ab3ba8ea7bbbfac8
https://doi.org/10.1093/med/9780197583425.003.0015
https://doi.org/10.1093/med/9780197583425.003.0015
Publikováno v:
Journal of Molecular Neuroscience. 51:788-791
We assessed the ex vivo reactivity of peptidic constructs of Tet1 (analog of tetanus toxin non-virulent C fragment) with sequence homology to the cysteine-active site of thioredoxin (Tet1THO) or tetralysine (Tet1PLYS) with oxidative species or axonop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450fe43c13d31c248f0c4625f6099165
https://doi.org/10.1007/s12031-013-0065-x
https://doi.org/10.1007/s12031-013-0065-x
Publikováno v:
Brain research. 1657
Motoneuron degeneration is the hallmark of amyotrophic lateral sclerosis (ALS). The cause and predisposing factors for sporadic ALS are still unknown. Exposure to a specific environmental risk factors in subjects with a susceptibility genotype may in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f4038ae613333833d60c67ff856b82
https://pubmed.ncbi.nlm.nih.gov/28048973
https://pubmed.ncbi.nlm.nih.gov/28048973
Autor:
G. Nicolas, Desire Tshala-Katumbay, Victor Monterroso, A. L. Ramos, E. Couchi, Jill S. Wentzell, Doris Kretzschmar, Roman M. Kassa, M. C. Lecomte, Mihail S. Iordanov
Publikováno v:
Journal of Molecular Neuroscience. 47:631-638
We use 1,2-diacetylbenzene (1,2-DAB) to probe molecular mechanisms of proximal giant neurofilamentous axonopathy (PGNA), a pathological hallmark of amyotrophic lateral sclerosis. The spinal cord proteome of rodents displaying 1,2-DAB PGNA suggests a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb8929af2f11946a7e6199fbea0098c
https://doi.org/10.1007/s12031-011-9699-8
https://doi.org/10.1007/s12031-011-9699-8
Publikováno v:
Neurology. 90:e94-e95
A 22-year-old woman presented with photopsia, sensory loss, and paresthesia over both lower extremities, visual scotomas, and painless binocular vision loss over 5 months. MRI showed T2 hyperintensities near the optic chiasm (figure 1, B and C), floo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c767f61a0e1af129c353ebe15f7e5606
https://doi.org/10.1212/wnl.0000000000004760
https://doi.org/10.1212/wnl.0000000000004760
Gene, Cell, and Axon Changes in the Familial Amyotrophic Lateral Sclerosis Mouse Sensorimotor Cortex
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 68:59-72
Lower motoneuron abnormalities have been extensively documented in the murine model of familial amyotrophic lateral sclerosis, whereas information on corticospinal neurons in these mice is very limited. We investigated 1) mRNA levels of inflammation-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884665c8000d5f3676ebe6d157b8544e
https://doi.org/10.1097/nen.0b013e3181922572
https://doi.org/10.1097/nen.0b013e3181922572
Publikováno v:
Experimental Neurology. 215:77-86
The neurodegenerative disease amyotrophic lateral sclerosis affects lower motoneurons and corticospinal cells. Mice expressing human mutant superoxide dismutase (SOD)1 provide widely investigated models of the familial form of disease, but informatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13733e96e55c901836e50f11be83f95
https://doi.org/10.1016/j.expneurol.2008.09.005
https://doi.org/10.1016/j.expneurol.2008.09.005
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 1, Pp 121-133 (2007)
Involvement of P2X1 and P2X2 purinergic receptors in motoneuron response to injury was investigated with Western blotting and immunohistochemistry and correlated with motoneuron loss, Bcl-2 expression, nitric oxide synthase induction and glial activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6ef2d5ad1f211b2670b4ed6244eac7
https://doi.org/10.1016/j.nbd.2006.08.020
https://doi.org/10.1016/j.nbd.2006.08.020