Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Roman Kula"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Sildenafil (Viagra), the first approved and widely used oral drug for the treatment of erectile dysfunction, was occasionally associated with life-threatening ventricular arrhythmias in patients. Since inward rectifier potassium current (IK1) may con
Externí odkaz:
https://doaj.org/article/b1861e74910d4693ba4e49759f037afe
Publikováno v:
Children, Vol 10, Iss 4, p 741 (2023)
The increasing attendance of paediatric emergency departments has become a serious health issue. To reduce an elevated burden of medical errors, inevitably caused by a high level of stress exerted on emergency physicians, we propose potential areas f
Externí odkaz:
https://doaj.org/article/7f3f5a77d2924450904087c0bde3e427
Publikováno v:
Biomedical Papers, Vol 161, Iss 2, Pp 187-196 (2017)
Background and Aims: Delirium is an acute brain dysfunction and a frequent complication in critically ill patients. When present it significantly worsens the prognosis of patients. The aim of this study was to evaluate the incidence of delirium and r
Externí odkaz:
https://doaj.org/article/177f5a728e744fcea10ed55c58d23028
Autor:
Radovan Uvizl, Milan Adamus, Vladimir Cerny, Ladislav Dusek, Jiri Jarkovsky, Vladimir Sramek, Martin Matejovic, Petr Stourac, Roman Kula, Jan Malaska, Pavel Sevcik
Publikováno v:
Biomedical Papers, Vol 160, Iss 2, Pp 287-297 (2016)
Background: Severe sepsis/septic shock is associated with high mortality. In Central Europe, there is a dearth of information on the prevalence and treatment of severe sepsis. The EPOSS (Data-based Evaluation and Prediction of Outcome in Severe Sepsi
Externí odkaz:
https://doaj.org/article/5b72589d26bf4f33b038b7bae9e5219c
Publikováno v:
Progress in Biophysics and Molecular Biology. 157:11-17
The distribution of data presented in many electrophysiological studies is presumed to be normal without any convincing evidence. To test this presumption, the cell membrane capacitance and magnitude of inward rectifier potassium currents were record
Autor:
Roman Kula
Publikováno v:
Critical Care Medicine. 50:e693-e694
Autor:
Roman, Kula
Publikováno v:
Klinicka mikrobiologie a infekcni lekarstvi. 26(4)
The aim of this mini-review is to draw attention to the risk aspects associated with antibiotic treatment in critically ill patients. These include antibiotic underdosing in the early phase of sepsis if treatment is governed by pharmacopoeia and unne
Autor:
Nuno Jorge Dourado Ramalho, Olga Švecová, Roman Kula, Milena Šimurdová, Jiří Šimurda, Markéta Bébarová
Publikováno v:
Pflugers Archiv : European journal of physiology. 474(3)
Bronchodilator aminophylline may induce atrial or less often ventricular arrhythmias. The mechanism of this proarrhythmic side effect has not been fully explained. Modifications of inward rectifier potassium (Kir) currents including I
Publikováno v:
Neuro endocrinology letters. 42(5)
The effect in smokers of nicotine withdrawal following surgery may contribute to the development of postoperative delirium. Nicotine is known to increase myocardial oxygen demand, coronary vasoconstriction, and may cause platelet activation leading t
Autor:
Kateřina Sobotková, Milan Urík, Klára Perce, Barbora Petrová, Soňa Šikolová, Michal Bartoš, Jana Jančíková, Roman Kula, Petr Jabandžiev
Publikováno v:
Ear, Nose & Throat Journal. :014556132211062
Fourth branchial cleft anomalies are rare head and neck congenital lesions seen in children. They present as a neck inflammatory mass and arise essentially on the left side of the neck. We report the case of a 7-month-old female with a mass of the ne