Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Roman Goněc"'
The risk of second primary malignancies in colorectal cancer patients using calcium channel blockers
Autor:
Jana Halámková, Lucia Bohovicová, Lucie Pehalová, Tomáš Kazda, Roman Goněc, Teodor Staněk, Lucie Mouková, Dagmar Adámková Krákorová, Šárka Kozáková, Marek Svoboda, Regina Demlová, Lucie Gabrielová, Lenka Hernychová, Igor Kiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Calcium channel blockers are among the most commonly used agents in the treatment of cardiovascular diseases. There are several known side-effects associated with their long-term use, whereas other potential adverse effects are yet to be pro
Externí odkaz:
https://doaj.org/article/6d25c6199bb14f1786d61c2c93398684
Autor:
Jana Halámková, Lucia Bohovicová, Lucie Pehalová, Roman Goněc, Teodor Staněk, Tomáš Kazda, Lucie Mouková, Dagmar Adámková Krákorová, Šárka Kozáková, Marek Svoboda, Regina Demlová, Igor Kiss
Publikováno v:
Cancers, Vol 14, Iss 7, p 1699 (2022)
An increasing number of studies has brought evidence of the protective role of statin use against different types of cancer. However, data on their association with second primary malignancies (SPMs) are lacking. The purpose of this study was to dete
Externí odkaz:
https://doaj.org/article/6e7ddf0a12b344d38bdead9675bcd6a5
Autor:
Roman Goněc
Publikováno v:
Praktické lékárenství. 18:9-13
Publikováno v:
European Pharmaceutical Journal. 69:84-86
Autoimmune adverse effects of immune checkpoint inhibitors (ICIs) are rare but may be life-threatening. We performed a retrospective analysis of the immune-related adverse effects (irAEs) of ICIs in the Masaryk Memorial Cancer Institute (MMCI) from 2
Publikováno v:
Medicína pro praxi. 17:125-128
K hlavnim rizikům onkologicke lecby, na ktera ve sve denni praxi naraži prakticti lekaři, patři lekove interakce a řeseni nežadoucich ucinků. Lekove interakce jsou castějsi při lecbě starsich polymorbidnich pacientů. Onkologicti pacienti j
Publikováno v:
Onkologie. 12:283-286
interakce s lecivými připravky se mohou objevit na vsech urovnich a jejich neuznani může vest k předavkovani nebo nedostatecne lecbě zavažnými klinickými nasledky. Interakce s lecivy v onkologii zahrnuji interakce v cilene terapii, přicemž
Publikováno v:
Pharmaceutical development and technology. 26(1)
The pharmaceutical industry has to tackle the explosion of high amounts of poorly soluble APIs. This phenomenon leads to numerous sophisticated solutions. These include the use of multifactorial data analysis identifying correlations between the comp
Autor:
Aleš, Franc, David, Vetchý, Pavlína, Vodáčková, Roman, Kubaľák, Lenka, Jendryková, Roman, Goněc
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 67(5-6)
Tablets are the most frequently employed dosage form. Their advantage lies in their availability, easy administration, good stability, and low price. The easiest technology to produce tablets is direct compression, even though the use of the method r
Publikováno v:
Acta Pharmaceutica
Volume 64
Issue 3
Acta Pharmaceutica, Vol 64, Iss 3, Pp 355-367 (2014)
Volume 64
Issue 3
Acta Pharmaceutica, Vol 64, Iss 3, Pp 355-367 (2014)
The article describes the development and production of tablets using direct compression of powder mixtures. The aim was to describe the impact of filler particle size and the time of lubricant addition during mixing on content uniformity according t
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 109
Warfarin is intensively discussed drug with narrow therapeutic range. There have been cases of bleeding attributed to varying content or altered quality of the active substance. Factor analysis is useful for finding suitable technological parameters