Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Roman G. Timoshchenko"'
Autor:
Jaime M. Brozowski, Roman G. Timoshchenko, D. Stephen Serafin, Brittney Allyn, Jessica Koontz, Emily M. Rabjohns, Rishi R. Rampersad, Yinshi Ren, Amanda M. Eudy, Taylor F. Harris, David Abraham, Daniel Mattox, Clinton T. Rubin, Matthew J. Hilton, Janet Rubin, Nancy L. Allbritton, Matthew J. Billard, Teresa K. Tarrant
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells
Externí odkaz:
https://doaj.org/article/124f702e78d146ed89416332f38c7248
Autor:
Emily M. Rabjohns, Clinton T. Rubin, Matthew J. Billard, Brittney Allyn, Taylor F. Harris, Roman G. Timoshchenko, Nancy L. Allbritton, Jaime M. Brozowski, David H. Abraham, Donald Serafin, Jessica Koontz, Matthew J. Hilton, Yinshi Ren, Janet Rubin, Teresa K. Tarrant, Daniel E Mattox, Amanda M Eudy
Background The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells are still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41a9e3f319fabeb9612ccfcba0f582ee
https://doi.org/10.21203/rs.3.rs-310081/v1
https://doi.org/10.21203/rs.3.rs-310081/v1
Autor:
Denise Esserman, Brittney Allyn, Daniel E Mattox, Jaime M. Brozowski, Maria F. Sassano, D. Stephen Serafin, Roman G. Timoshchenko, David P. Siderovski, Matthew J. Billard, Young K. Truong, Teresa K. Tarrant
Chemerin receptor (CMKLR1) is a G protein-coupled receptor (GPCR) implicated in macrophage-mediated inflammation and in several forms of human arthritis. Analogous to other GPCR, CMKLR1 is likely regulated by G protein-coupled receptor kinase (GRK) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039d41c608327229aa8aaa666fabdda3
https://europepmc.org/articles/PMC6584946/
https://europepmc.org/articles/PMC6584946/
Autor:
Paola A. Gehrig, Charlene M. Santos, Craig R. Lee, Ramesh K. Ramanathan, Suzan K. Hanna, Roman G. Timoshchenko, William C. Zamboni, Victoria L. Bae-Jump, Gina Song, Teresa K. Tarrant, David A. Barrow, Taylor F. White
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 11:1797-1807
Nanoparticles (NPs) are cleared by monocytes and macrophages. Chemokines CCL2 and CCL5 are key mediators for recruitment of these immune cells into tumors and tissues. The purpose of this study was to investigate effects of CCL2 and CCL5 on the pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f37e2344d163657362feef7b37992f
https://doi.org/10.1016/j.nano.2015.05.007
https://doi.org/10.1016/j.nano.2015.05.007
Autor:
D. Stephen Serafin, M.W. McGinnis, Roman G. Timoshchenko, Dhavalkumar D. Patel, David P. Siderovski, Nelson J. Chao, Oded Foreman, David Lee, William Lento, Denise Esserman, Matthew J. Billard, Teresa K. Tarrant
Publikováno v:
Journal of Leukocyte Biology. 94:1243-1251
Chemokine receptor interactions coordinate leukocyte migration in inflammation. Chemokine receptors are GPCRs that when activated, are phosphorylated by GRKs to turn off G protein-mediated signaling yet recruit additional signaling machinery. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65acbf332fa359147d8271d1159212d
https://doi.org/10.1189/jlb.0213097
https://doi.org/10.1189/jlb.0213097
Autor:
David J. Fitzhugh, M.W. McGinnis, Roman G. Timoshchenko, Joel S. Parker, Jaime M. Brozowski, D. Stephen Serafin, Nancy Klauber-DeMore, Jonathan S. Serody, G. Gary Sahagian, Young K. Truong, Ruth A. Lininger, Teresa K. Tarrant, Maria F. Sassano, Matthew J. Billard
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152856 (2016)
PLoS ONE
PLoS ONE
Triple negative breast cancer (TNBC) is a heterogeneous disease that has a poor prognosis and limited treatment options. Chemokine receptor interactions are important modulators of breast cancer metastasis; however, it is now recognized that quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403efa10bd7f2f2c0dce8408ac790355
http://europepmc.org/articles/PMC4822790?pdf=render
http://europepmc.org/articles/PMC4822790?pdf=render
Publikováno v:
Current Allergy and Asthma Reports. 12:495-510
Many biologic agents that were first approved for the treatment of malignancies are now being actively investigated and used in a variety of autoimmune diseases such as rheumatoid arthritis (RA), antineutrophil cytoplasmic antibody (ANCA)-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be059c4ed88584b0c9fb231705bedd6
https://doi.org/10.1007/s11882-012-0307-y
https://doi.org/10.1007/s11882-012-0307-y
Autor:
Patricia L. Lugar, Luanna Yang, Shaili N. Shah, Kristy L. Richards, Paula Scotland, D. Stephen Serafin, Roman G. Timoshchenko, Matthew J. Billard, Teresa K. Tarrant
Publikováno v:
Journal of Allergy and Clinical Immunology. 137:AB179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::059430af8187e0245375c1783c20ad2f
https://doi.org/10.1016/j.jaci.2015.12.720
https://doi.org/10.1016/j.jaci.2015.12.720
Autor:
M.W. McGinnis, Oded Foreman, Brian K. Buckley, Patrick M. Giguère, Teresa K. Tarrant, Peng Liu, Denise Esserman, Roman G. Timoshchenko, David P. Siderovski, Matthew J. Billard, Geneviève Laroche
Publikováno v:
Molecular immunology. 54(2)
Polymorphism at the GPSM3 gene locus is inversely associated with four systemic autoimmune diseases, including rheumatoid arthritis and ankylosing spondylitis. G-protein signaling modulator-3 (GPSM3) expression is most pronounced in myeloid cells, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a6942714af3f07240b0120b461d471
https://pubmed.ncbi.nlm.nih.gov/23280397
https://pubmed.ncbi.nlm.nih.gov/23280397
Autor:
Teresa K, Tarrant, Peng, Liu, Rishi R, Rampersad, Denise, Esserman, Lisa R, Rothlein, Roman G, Timoshchenko, Marcus W, McGinnis, David J, Fitzhugh, Dhavalkumar D, Patel, Alan M, Fong
Publikováno v:
Arthritis and rheumatism. 64(5)
CX(3) CR1 is a chemokine receptor that uniquely binds to its ligand fractalkine (CX(3) CL1) and has been shown to be important in inflammatory arthritis responses, largely due to its effects on cellular migration. This study was undertaken to test th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19f41993ccaf12f6b91e8f8744cf9f5d
https://pubmed.ncbi.nlm.nih.gov/22144035
https://pubmed.ncbi.nlm.nih.gov/22144035