Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roman E Reggiardo"'
Autor:
Eric W. Martin, Jana Krietsch, Roman E. Reggiardo, Rebekah Sousae, Daniel H. Kim, E. Camilla Forsberg
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Hematopoietic stem cells (HSCs) have the capacity to differentiate into vastly different types of mature blood cells. The epigenetic mechanisms regulating the multilineage ability, or multipotency, of HSCs are not well understood. To test th
Externí odkaz:
https://doaj.org/article/a593727d6bef415a8611f530138a2328
Autor:
Eric W Martin, Alessandra Rodriguez y Baena, Roman E Reggiardo, Atesh K Worthington, Connor S Mattingly, Donna M Poscablo, Jana Krietsch, Michael T McManus, Susan Carpenter, Daniel H Kim, E Camilla Forsberg
Publikováno v:
Stem Cells. 41:520-539
Epigenetic mechanisms regulate the multilineage differentiation capacity of hematopoietic stem cells (HSCs) into a variety of blood and immune cells. Mapping the chromatin dynamics of functionally defined cell populations will shed mechanistic insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a9a80ed423a34b475f6b469caf875df
https://doi.org/10.1093/stmcls/sxad022
https://doi.org/10.1093/stmcls/sxad022
Mutant KRAS regulates transposable element (TE) RNA and interferon-stimulated gene (ISG) expression, but it remains unclear whether diverse mutations in KRAS affect different TE RNAs throughout the genome. We analyzed the transcriptomes of 3D human l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb6bfc37e8f51d82499e8328220fbe5d
https://doi.org/10.1101/2023.02.27.530369
https://doi.org/10.1101/2023.02.27.530369
Publikováno v:
Advances in experimental medicine and biology. 1363
Long noncoding RNAs (lncRNAs) are promising candidates as biomarkers of inflammation and cancer. LncRNAs have several properties that make them well-suited as molecular markers of disease: (1) many lncRNAs are expressed in a tissue-specific manner, (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3269b863fef69cfbf0046054f77361f
https://pubmed.ncbi.nlm.nih.gov/35220568
https://pubmed.ncbi.nlm.nih.gov/35220568
Autor:
Reem Khojah, Roman E. Reggiardo, Mehmet Ozen, Sreelakshmi Velandi Maroli, David Carrillo, Utkan Demirci, Daniel H. Kim
Extracellular RNAs (exRNAs) are actively secreted from cells in membrane-bound extracellular vesicles (EVs). Diverse classes of RNAs are secreted as exRNAs, including messenger RNAs (mRNAs), long noncoding RNAs (lncRNAs), and transposable element RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::033bee70129c3cbb188b30d506f9b7ef
https://doi.org/10.1101/2022.02.23.481574
https://doi.org/10.1101/2022.02.23.481574
Publikováno v:
Long Noncoding RNA ISBN: 9783030920333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f0fe74c7945a30da5a0a0623e98453
https://doi.org/10.1007/978-3-030-92034-0_7
https://doi.org/10.1007/978-3-030-92034-0_7
Autor:
Jana Krietsch, Eric W. Martin, E. Camilla Forsberg, Roman E. Reggiardo, Daniel H. Kim, Rebekah Sousae
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Epigenetics & Chromatin
Epigenetics & Chromatin
Hematopoietic stem cells (HSCs) have the capacity to differentiate into vastly different types of mature blood cells. The epigenetic mechanisms regulating the multilineage ability, or multipotency of HSCs are not well understood. To test the hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2933a56abbf3b309b7c7b1a00e2c7baa
https://doi.org/10.1186/s13072-020-00377-1
https://doi.org/10.1186/s13072-020-00377-1
Autor:
Roman E. Reggiardo, Sreelakshmi Velandi Maroli, Haley Halasz, Mehmet Ozen, Eva Hrabeta-Robinson, Amit Behera, Vikas Peddu, David Carrillo, Erin LaMontagne, Lila Whitehead, Eejung Kim, Shivani Malik, Jason Fernandes, Georgi Marinov, Eric Collisson, Angela Brooks, Utkan Demirci, Daniel H. Kim
Publikováno v:
Cell reports. 40(3)
RAS genes are the most frequently mutated oncogenes in cancer, yet the effects of oncogenic RAS signaling on the noncoding transcriptome remain unclear. We analyzed the transcriptomes of human airway and bronchial epithelial cells transformed with mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f22780d05c0a495f7d016be6541390
https://pubmed.ncbi.nlm.nih.gov/35858545
https://pubmed.ncbi.nlm.nih.gov/35858545
Autor:
Collisson E, Georgi K. Marinov, Carrillo D, Mehmet Ozgun Ozen, Eejung Kim, Malik S, Roman E. Reggiardo, Erin LaMontagne, Daniel H. Kim, Utkan Demirci, Lila Whitehead, Haley Halasz, Maroli Sv, Jason D Fernandes
RAS genes are the most frequently mutated oncogenes in cancer. However, the effects of oncogenic RAS signaling on the noncoding transcriptome are unclear. We analyzed the transcriptomes of human airway epithelial cells transformed with mutant KRAS to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9a743c7d6f9f98df0cc49011a51115
https://doi.org/10.1101/2020.11.04.367771
https://doi.org/10.1101/2020.11.04.367771
Autor:
Michael J Litt, Masoud Ghamari-Langroudi, Valerie Chen, Roman E. Reggiardo, Erica J. P. Anderson, Isin Cakir, Roger D. Cone, Glenn L. Millhauser
Publikováno v:
Journal of Neuroendocrinology. 31:e12670
Energy stores in fat tissue are determined in part by the activity of hypothalamic neurones expressing the melanocortin-4 receptor (MC4R). Even a partial reduction in MC4R expression levels in mice, rats or humans produces hyperphagia and morbid obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6642de981343d0701d11e1b9cf1bc2
https://doi.org/10.1111/jne.12670
https://doi.org/10.1111/jne.12670