Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Roman Bayandin"'
Autor:
Roman Bayandin, Alexander N. Sinyakov, Georgy A. Nevinsky, Vincent Parissi, Anne Caumont, Laura Tarrago-Litvak, Olga D. Zakharova, Elena L. Vasyutina, Vladimir A. Ryabinin, Simon Litvak, Vaea Richard de Soultrait, Ekaterina A. Yurchenko
Publikováno v:
European Journal of Medicinal Chemistry. 35:989-1000
Human immunodeficiency virus type 1 (HIV-1) integrase (IN) is an essential enzyme in the life cycle of the retrovirus, responsible for catalysing the insertion of the viral genome into the host cell chromosome. For this reason it provides an attracti
Autor:
Gordon Jamieson, Vaea Richard de Soultrait, Roman Bayandin, Laura Tarrago-Litvak, Georgy A. Nevinsky, Vincent Parissi, Anne Caumont, Simon Litvak, Michel Fournier, Olga D. Zakharova
Publikováno v:
FEBS Letters. 455:154-158
Retroviral integrase (IN) catalyzes the integration of double-stranded viral DNA into the host cell genome. The reaction can be divided in two steps: 3′-end processing and DNA strand transfer. Here we studied the effect of short oligonucleotides (O