Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Roman Błaszczyk"'
Autor:
Paulina Pilanc, Kamil Wojnicki, Adria-Jaume Roura, Salwador Cyranowski, Aleksandra Ellert-Miklaszewska, Natalia Ochocka, Bartłomiej Gielniewski, Marcin M. Grzybowski, Roman Błaszczyk, Paulina S. Stańczak, Paweł Dobrzański, Bozena Kaminska
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastomas (GBM) are the common and aggressive primary brain tumors that are incurable by conventional therapies. Immunotherapy with immune checkpoint inhibitors is not effective in GBM patients due to the highly immunosuppressive tumor microenvir
Externí odkaz:
https://doaj.org/article/f18cf054fb784a82904cd1fc12251b85
Autor:
Marcin Mikołaj Grzybowski, Paulina Seweryna Stańczak, Paulina Pomper, Roman Błaszczyk, Bartłomiej Borek, Anna Gzik, Julita Nowicka, Karol Jędrzejczak, Joanna Brzezińska, Tomasz Rejczak, Nazan Cemre Güner-Chalimoniuk, Agnieszka Kikulska, Michał Mlącki, Jolanta Pęczkowicz-Szyszka, Jacek Olczak, Adam Gołębiowski, Karolina Dzwonek, Paweł Dobrzański, Zbigniew Zasłona
Publikováno v:
Cancers; Volume 14; Issue 16; Pages: 3967
Background: Arginases play essential roles in metabolic pathways, determining the fitness of both immune and tumour cells. Along with the previously validated role of ARG1 in cancer, the particular significance of ARG2 as a therapeutic target has eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de43a0e8b5529073a0d618a4723b30a8
https://doi.org/10.3390/cancers14163967
https://doi.org/10.3390/cancers14163967
Autor:
Tadeusz Gajda, Marek Sochacki, Marek Cypryk, Roman Błaszczyk, Grzegorz Krasiński, Ewelina Drabik
Publikováno v:
Journal of the American Society for Mass Spectrometry
Electron ionization mass spectrometry and density functional theory (DFT) calculations have been used to study the fragmentation of diastereoisomers of protected 1,2-diaminoalkylphosphonic acids. The loss of a diethoxyphosphoryl group and the elimina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd43b39b9cf08ed9f965b38ca10e4d0c
https://doi.org/10.1007/s13361-012-0556-y
https://doi.org/10.1007/s13361-012-0556-y
Autor:
Tomasz M. Grzywa, Anna Sosnowska, Zuzanna Rydzynska, Michal Lazniewski, Dariusz Plewczynski, Klaudia Klicka, Milena Malecka-Gieldowska, Anna Rodziewicz-Lurzynska, Olga Ciepiela, Magdalena Justyniarska, Paulina Pomper, Marcin M. Grzybowski, Roman Blaszczyk, Michal Wegrzynowicz, Agnieszka Tomaszewska, Grzegorz Basak, Jakub Golab, Dominika Nowis
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Grzywa et al. show that early CD71+ erythroid cells expand in the spleen of anemic mice and in humans and suppress T-cell activation. These results provide insight into the role of CECs in the immune response regulation.
Externí odkaz:
https://doaj.org/article/eb750972eff04eb185f5c3967b7d2308
Publikováno v:
Applied Sciences, Vol 13, Iss 16, p 9201 (2023)
The aim of this study was to develop an analytical method for selective determination of OATD-02 by high-performance liquid chromatography (HPLC) with post-column derivatization and fluorescence detection (FLD). OATD-02, a new boronic acid derivative
Externí odkaz:
https://doaj.org/article/8ef73bdfc5c7465fa5218c3957cda005
Publikováno v:
Rapid communications in mass spectrometry : RCM. 24(16)
Diastereoisomers of diethyl 5-substituted (2-thioxo-imidazolidin-4-yl)phosphonates, which can be regarded as protected diethyl 1,2-diaminoalkylphosphonates, have been analyzed by electron ionization mass spectrometry. Significant differences in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e3502df4a7396baae284532bad6a0d1
https://pubmed.ncbi.nlm.nih.gov/20658678
https://pubmed.ncbi.nlm.nih.gov/20658678
Autor:
Roman Błaszczyk
Publikováno v:
Synlett. 2008:299-300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ab090e2e52ca04c362122aa134ca42
https://doi.org/10.1055/s-2007-1000842
https://doi.org/10.1055/s-2007-1000842
Autor:
Malgorzata Czystowska-Kuzmicz, Anna Sosnowska, Dominika Nowis, Kavita Ramji, Marta Szajnik, Justyna Chlebowska-Tuz, Ewa Wolinska, Pawel Gaj, Magdalena Grazul, Zofia Pilch, Abdessamad Zerrouqi, Agnieszka Graczyk-Jarzynka, Karolina Soroczynska, Szczepan Cierniak, Robert Koktysz, Esther Elishaev, Slawomir Gruca, Artur Stefanowicz, Roman Blaszczyk, Bartlomiej Borek, Anna Gzik, Theresa Whiteside, Jakub Golab
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Cancer cells employ a variety of ways to escape the immune system. Here, the authors show that ovarian cancer cells produce small extracellular vescicles containing arginase 1 that are taken up by dendritic cells in the draining lymph nodes, resultin
Externí odkaz:
https://doaj.org/article/c326eb351422420292defaecb97f1410
Autor:
Anna Sosnowska, Justyna Chlebowska-Tuz, Pawel Matryba, Zofia Pilch, Alan Greig, Artur Wolny, Tomasz M. Grzywa, Zuzanna Rydzynska, Olga Sokolowska, Tomasz P. Rygiel, Marcin Grzybowski, Paulina Stanczak, Roman Blaszczyk, Dominika Nowis, Jakub Golab
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Immunotherapy has demonstrated significant activity in a broad range of cancer types, but still the majority of patients receiving it do not maintain durable therapeutic responses. Amino acid metabolism has been proposed to be involved in the regulat
Externí odkaz:
https://doaj.org/article/07d158283324431ba6734d685c57a6a0