Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Roman A Blaheta"'
Autor:
Berlise Yengwa Bakam, Romeo Urich Fosso, Timothy Grein, Derek Tantoh Ndinteh, Sebastian Maxeiner, Stéphane Zingue, Roman A Blaheta, Dieudonne Njamen
Publikováno v:
Journal of Functional Foods, Vol 114, Iss , Pp 106088- (2024)
Pumpkin seeds are claimed to treat prostate tumour/cancer. The in vitro (ability to inhibit cell growth through MTT assay) and in vivo (ability to prevent testosterone-induced BPH in rats at the doses of 125, 250, 500 and 1000 mg/kg BW) of six edible
Externí odkaz:
https://doaj.org/article/ef768c7df15b4f42bb8cc1b9b25e80c6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Herbal medicines are becoming increasingly popular among patients because they are well tolerated and do not exert severe side effects. Nevertheless, they receive little consideration in therapeutic settings. The present article reviews the current s
Externí odkaz:
https://doaj.org/article/635da9dbbff144c086109b75d5c371f1
Autor:
Eva Juengel, Pascal Schnalke, Jochen Rutz, Sebastian Maxeiner, Felix K.-H. Chun, Roman A. Blaheta
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1630 (2021)
Tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors predominate as first-line therapy options for renal cell carcinoma. When first-line TKI therapy fails due to resistance development, an optimal second-line therapy has not yet been es
Externí odkaz:
https://doaj.org/article/d658e594097e425e983507c22ab51534
Autor:
Igor Tsaur, Anita Thomas, Eva Juengel, Sebastian Maxeiner, Timothy Grein, Quynh Chi Le, Veronika Muschta, Jochen Rutz, Felix K. H. Chun, Roman A. Blaheta
Publikováno v:
Biology, Vol 10, Iss 10, p 1007 (2021)
The serum level of soluble (s)E-cadherin is elevated in several malignancies, including prostate cancer (PCa). This study was designed to investigate the effects of sE-cadherin on the behavior of PCa cells in vitro, with the aim of identifying a pote
Externí odkaz:
https://doaj.org/article/4096ec2ba66a4e37835f6aa48dba26ac
Autor:
Hui Xie, Jochen Rutz, Sebastian Maxeiner, Timothy Grein, Anita Thomas, Eva Juengel, Felix K.-H. Chun, Jindrich Cinatl, Axel Haferkamp, Igor Tsaur, Roman A. Blaheta
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4682
Combined cisplatin–gemcitabine (GC) application is standard for treating muscle-invasive bladder cancer. However, since rapid resistance to treatment often develops, many patients turn to supplements in the form of plant-based compounds. Sulforapha
Autor:
Jochen Rutz, Sebastian Maxeiner, Timothy Grein, Marlon Sonnenburg, Salma El Khadir, Nino Makhatelashvili, Johanna Mann, Hui Xie, Jindrich Cinatl, Anita Thomas, Felix K.-H. Chun, Axel Haferkamp, Roman A. Blaheta, Igor Tsaur
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 10996
Combined cisplatin–gemcitabine treatment causes rapid resistance development in patients with advanced urothelial carcinoma. The present study investigated the potential of the natural isothiocyanates (ITCs) allyl-isothiocyanate (AITC), butyl-isoth
Autor:
Eva Juengel, Jasmina Makarević, Michael Reiter, Jens Mani, Igor Tsaur, Georg Bartsch, Axel Haferkamp, Roman A. Blaheta
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 4, Pp 291-300 (2014)
Inhibitors of the mammalian target of rapamycin (mTOR) have improved the treatment of renal cell carcinoma (RCC). However, chronic drug exposure may trigger resistance, limiting the utility of these agents. The metastatic behavior of RCC cells, susce
Externí odkaz:
https://doaj.org/article/fff53da712ce4e9790e0809b4b438f46
Autor:
Derek Tantoh Ndinteh, Sebastian Maxeiner, Stéphane Zingue, Jochen Rutz, Eva Jüngel, Roman A. Blaheta, Berlise Yengwa Bakam, Charline Florence Awounfack, Dieudonné Njamen
Publikováno v:
Biologia. 75:2053-2062
Despite much recent progress in prostate research, Benign prostatic hyperplasia (BPH) and prostate cancer continue to represent major causes of morbidity and mortality in men. In our ongoing search of natural alternatives to treat these prostate dise
Autor:
Anita Thomas, Kimberly Sue Slade, Roman A. Blaheta, Sascha D. Markowitsch, Philipp Stenzel, Katrin E. Tagscherer, Wilfried Roth, Mario Schindeldecker, Martin Michaelis, Florian Rothweiler, Jaroslav Cinatl, Robert Dotzauer, Olesya Vakhrusheva, Maarten Albersen, Axel Haferkamp, Eva Juengel, Jindrich Cinatl, Igor Tsaur
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1683
Whereas the lack of biomarkers in penile cancer (PeCa) impedes the development of efficacious treatment protocols, preliminary evidence suggests that c-MET and associated signaling elements may be dysregulated in this disorder. In the following study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2960efb4e5907a67d482a14600addf45
https://kar.kent.ac.uk/95208/1/cancers-14-01683-v2.pdf
https://kar.kent.ac.uk/95208/1/cancers-14-01683-v2.pdf
Autor:
Igor, Tsaur, Roman A, Blaheta, Robert, Dotzauer, Maximilian P, Brandt, Giorgio, Gandaglia, Ioanel, Sinescu, Cristian, Mirvald, Jonathan, Olivier, Cristian, Surcel, Christian, Surcel
Publikováno v:
World journal of urology.
Focal therapy (FT) is gaining increasing acceptance in the management of localized prostate cancer particularly due to its favorable safety. Preliminary evidence suggests advantageous utilization of local treatment in the field of oligometastatic pro