Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Roman, Zubarev"'
Autor:
Franz F. Dressler, Falk Diedrichs, Deema Sabtan, Sofie Hinrichs, Christoph Krisp, Timo Gemoll, Martin Hennig, Paulina Mackedanz, Mareile Schlotfeldt, Hannah Voß, Anne Offermann, Jutta Kirfel, Marie C. Roesch, Julian P. Struck, Mario W. Kramer, Axel S. Merseburger, Christian Gratzke, Dominik S. Schoeb, Arkadiusz Miernik, Hartmut Schlüter, Ulrich Wetterauer, Roman Zubarev, Sven Perner, Philipp Wolf, Ákos Végvári
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Urothelial bladder cancer (UC) has a wide tumor biological spectrum with challenging prognostic stratification and relevant therapy-associated morbidity. Most molecular classifications relate only indirectly to the therapeutically relevant p
Externí odkaz:
https://doaj.org/article/5134170881c84f2485111eb97cd4a685
Autor:
Vittorio Fortino, Pia Anneli Sofia Kinaret, Michele Fratello, Angela Serra, Laura Aliisa Saarimäki, Audrey Gallud, Govind Gupta, Gerard Vales, Manuel Correia, Omid Rasool, Jimmy Ytterberg, Marco Monopoli, Tiina Skoog, Peter Ritchie, Sergio Moya, Socorro Vázquez-Campos, Richard Handy, Roland Grafström, Lang Tran, Roman Zubarev, Riitta Lahesmaa, Kenneth Dawson, Katrin Loeschner, Erik Husfeldt Larsen, Fritz Krombach, Hannu Norppa, Juha Kere, Kai Savolainen, Harri Alenius, Bengt Fadeel, Dario Greco
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Nanomaterials have a range of potential applications, however, toxicity remains a concern, limiting application and requiring extensive testing. Here, the authors report on a predictive framework made using a range of tests linking materials properti
Externí odkaz:
https://doaj.org/article/cd868a81e9ec4d95b4b5c073cf9197e3
Publikováno v:
Bio-Protocol, Vol 12, Iss 22 (2022)
Chemical proteomics focuses on the drug–target–phenotype relationship for target deconvolution and elucidation of the mechanism of action—key and bottleneck in drug development and repurposing. Majorly due to the limits of using chemically modi
Externí odkaz:
https://doaj.org/article/fc31464e193a43ada9f29d2dbc583328
Autor:
Pierre Sabatier, Christian M. Beusch, Radosveta Gencheva, Qing Cheng, Roman Zubarev, Elias S.J. Arnér
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102184- (2021)
Anticancer drugs that target cellular antioxidant systems have recently attracted much attention. Auranofin (AF) is currently evaluated in several clinical trials as an anticancer agent that targets the cytosolic and mitochondrial forms of the seleno
Externí odkaz:
https://doaj.org/article/2416c4c7c36649e9989635fa4100678e
Autor:
Audrey Gallud, Mathilde Delaval, Pia Kinaret, Veer Singh Marwah, Vittorio Fortino, Jimmy Ytterberg, Roman Zubarev, Tiina Skoog, Juha Kere, Manuel Correia, Katrin Loeschner, Zahraa Al‐Ahmady, Kostas Kostarelos, Jaime Ruiz, Didier Astruc, Marco Monopoli, Richard Handy, Sergio Moya, Kai Savolainen, Harri Alenius, Dario Greco, Bengt Fadeel
Publikováno v:
Advanced Science, Vol 7, Iss 22, Pp n/a-n/a (2020)
Abstract Despite considerable efforts, the properties that drive the cytotoxicity of engineered nanomaterials (ENMs) remain poorly understood. Here, the authors inverstigate a panel of 31 ENMs with different core chemistries and a variety of surface
Externí odkaz:
https://doaj.org/article/9a314f0b95114c6db6bf9e1d60d4034a
Autor:
Roman Zubarev
Publikováno v:
The Project Repository Journal. 15:38-41
Next-generation precision antibody profiling; from science fiction to reality The purpose of the TopSpec project is to develop tools to establish the sequence repertoire of human antibodies and their respective antigens, to better understand how the
Autor:
Galina Selivanova, Roman Zubarev, Thomas Helleday, Johan Hartman, Kaisa Lehti, Ulrika Joneborg, Elisabet Hjerpe, Joseph W. Carlson, Lidia Moyano-Galceran, Ali Rihani, Mikael S. Lindström, Torkild Visnes, Amir Ata Saei, Yao Shi, Xinsong Chen, Massimiliano Gaetani, Madhurendra Singh, Gema Sanz, Jiawei Zhu, Sylvain Peuget
qPCR primers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb5e020f996ad2f210eef0f851adb1a
https://doi.org/10.1158/0008-5472.22424566.v1
https://doi.org/10.1158/0008-5472.22424566.v1
Autor:
Galina Selivanova, Roman Zubarev, Thomas Helleday, Johan Hartman, Kaisa Lehti, Ulrika Joneborg, Elisabet Hjerpe, Joseph W. Carlson, Lidia Moyano-Galceran, Ali Rihani, Mikael S. Lindström, Torkild Visnes, Amir Ata Saei, Yao Shi, Xinsong Chen, Massimiliano Gaetani, Madhurendra Singh, Gema Sanz, Jiawei Zhu, Sylvain Peuget
Identification of the molecular mechanism of action (MoA) of bioactive compounds is a crucial step for drug development but remains a challenging task despite recent advances in technology. In this study, we applied multidimensional proteomics, sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1e96a96fa69c7e3fd4da2b5f960df9
https://doi.org/10.1158/0008-5472.c.6511810.v1
https://doi.org/10.1158/0008-5472.c.6511810.v1
Autor:
Galina Selivanova, Roman Zubarev, Thomas Helleday, Johan Hartman, Kaisa Lehti, Ulrika Joneborg, Elisabet Hjerpe, Joseph W. Carlson, Lidia Moyano-Galceran, Ali Rihani, Mikael S. Lindström, Torkild Visnes, Amir Ata Saei, Yao Shi, Xinsong Chen, Massimiliano Gaetani, Madhurendra Singh, Gema Sanz, Jiawei Zhu, Sylvain Peuget
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310bc9f0ed136c4a184c31154a92f339
https://doi.org/10.1158/0008-5472.22424575.v1
https://doi.org/10.1158/0008-5472.22424575.v1
Autor:
Galina Selivanova, Roman Zubarev, Thomas Helleday, Johan Hartman, Kaisa Lehti, Ulrika Joneborg, Elisabet Hjerpe, Joseph W. Carlson, Lidia Moyano-Galceran, Ali Rihani, Mikael S. Lindström, Torkild Visnes, Amir Ata Saei, Yao Shi, Xinsong Chen, Massimiliano Gaetani, Madhurendra Singh, Gema Sanz, Jiawei Zhu, Sylvain Peuget
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f163a52b7c59731c5822b98ce5e7b23
https://doi.org/10.1158/0008-5472.22424572.v1
https://doi.org/10.1158/0008-5472.22424572.v1