Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Roman, Fiedler"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3719 (2024)
Fluid overload in hemodialysis patients (HD) has been proven to be associated with inflammation. Elevated levels of the pro-inflammatory cytokine interleukin-6 (IL-6) appear to be inadequately counterbalanced by the anti-inflammatory cytokine interle
Externí odkaz:
https://doaj.org/article/e5e48868e229458e9f45999bd26ae34b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17550 (2023)
Hypervolemia is associated with inflammation in hemodialysis (HD) patients. How hypervolemia triggers inflammation is not entirely known. We initiated a cross-sectional study enrolling 40 hemodialysis patients who were categorized into normovolemic (
Externí odkaz:
https://doaj.org/article/8b4d6b568b7f4ad6bc97d80dc247b6b8
Autor:
Rusan Catar, Guido Moll, Julian Kamhieh-Milz, Christian Luecht, Lei Chen, Hongfan Zhao, Lucas Ernst, Kevin Willy, Matthias Girndt, Roman Fiedler, Janusz Witowski, Henning Morawietz, Olle Ringdén, Duska Dragun, Kai-Uwe Eckardt, Ralf Schindler, Daniel Zickler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
AbstractSystemic chronic microinflammation and altered cytokine signaling, with adjunct cardiovascular disease (CVD), endothelial maladaptation and dysfunction is common in dialysis patients suffering from end-stage renal disease and associated with
Externí odkaz:
https://doaj.org/article/2b5da9f8659e4b1c889dc9aee829ea9d
Autor:
Christof Ulrich, Anja Leonhardt, Bogusz Trojanowicz, Eric Seibert, Roman Fiedler, Matthias Girndt
Publikováno v:
European Journal of Inflammation, Vol 18 (2020)
The pathogenesis of the pruritus associated with chronic kidney disease-(CKD-aP) is not completely understood. Endocrine, metabolic, neuropathic, and inflammatory disorders were suspected to be the origin of CKD-aP. Based on the hypothesis which sugg
Externí odkaz:
https://doaj.org/article/1b42ef439623473fbcd7aae5332c0725
Autor:
Christof Ulrich, Leonie Kneser, Roman Fiedler, Julia Beckert, Susann Wildgrube, Eric Seibert, Sylvia Fick, Christoph Schäfer, Silke Markau, Bogusz Trojanowicz, Matthias Girndt
Publikováno v:
Toxins, Vol 13, Iss 12, p 839 (2021)
NLRP-3 inflammasome activation can result in interleukin-1β (IL-1β) release and inflammatory cell death (pyroptosis). Caspase-1 is able to trigger both processes. However, other caspases, caspase-4, -5 and -8, are believed to initiate pyroptosis wi
Externí odkaz:
https://doaj.org/article/0dc501f28719405ca8c71cd894f576b0
Autor:
Christian Henning, Christine Stübner, Seyed Hamidreza Arabi, Jörg Reichenwallner, Dariush Hinderberger, Roman Fiedler, Matthias Girndt, Simone Di Sanzo, Alessandro Ori, Marcus A. Glomb
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:3033-3046
Glycation significantly alters the physicochemical and biofunctional properties of proteins in foods and in vivo. In the present study, human serum albumin (HSA) as the major transporter of fatty acids was modified with glyoxal under physiological co
Autor:
Christof Ulrich, Susann Wildgrube, Roman Fiedler, Eric Seibert, Leonie Kneser, Sylvia Fick, Christoph Schäfer, Silke Markau, Bogusz Trojanowicz, Matthias Girndt
Publikováno v:
Toxins, Vol 12, Iss 11, p 675 (2020)
Hypertension is not only an integrative characteristic of hemodialysis (HD) patients but is also very common in the general population. There is evidence that the inflammatory cytokine IL-β, regulated by the NLRP3 inflammasome via caspase-1, contrib
Externí odkaz:
https://doaj.org/article/2a8d6a9e32f345498afb16119ee3bca0
Publikováno v:
Toxins, Vol 12, Iss 3, p 159 (2020)
Dysregulated fluid homeostasis is frequent in haemodialysis (HD) patients and is linked to inflammation which may be elicited by endotoxemia. The impact of hypervolemia on immune cells has not been studied in detail. Therefore, we analysed the hyperv
Externí odkaz:
https://doaj.org/article/4d243b81f55e4d1896682913f4212a96
Autor:
Daniel Zickler, Ralf Schindler, Kevin Willy, Peter Martus, Michael Pawlak, Markus Storr, Michael Hulko, Torsten Boehler, Marcus A Glomb, Kristin Liehr, Christian Henning, Markus Templin, Bogusz Trojanowicz, Christof Ulrich, Kristin Werner, Roman Fiedler, Matthias Girndt
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169024 (2017)
To increase the removal of middle-sized uremic toxins a new membrane with enhanced permeability and selectivity, called Medium Cut-Off membrane (MCO-Ci) has been developed that at the same time ensures the retention of albumin. Because many middle-si
Externí odkaz:
https://doaj.org/article/a90e66239040433d9a4cc810e67854b6
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Among the plethora of uraemic toxins the protein-bound indoxyl sulphate (IS) plays a prominent role in cardiovascular and renal disease progression. IS also appears to be involved in programmed cell death pathways. Regarding the h