Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Roman, Dziarski"'
Autor:
Chun-Kai Yang, Des R. Kashyap, Dominik A. Kowalczyk, David Z. Rudner, Xindan Wang, Dipika Gupta, Roman Dziarski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Mammalian peptidoglycan recognition proteins (PGRPs or PGLYRPs) kill bacteria through induction of synergistic oxidative, thiol, and metal stress. Tn-seq screening of Bacillus subtilis transposon insertion library revealed that mutants in th
Externí odkaz:
https://doaj.org/article/5242925f79604c4da0d4aa89b70fd364
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Nod2 is a pattern recognition receptor that modulates host innate immune responses and protects from inflammation, steatosis, and obesity. Obesity and inflammation are risk factors for hepatocellular carcinoma, however, the role of Nod2 in o
Externí odkaz:
https://doaj.org/article/717b3f606c254c97af41ede6ebd03a0e
Autor:
Ivan Rodriguez-Nunez, Tiffany Caluag, Kori Kirby, Charles N. Rudick, Roman Dziarski, Dipika Gupta
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Genetics plays a central role in susceptibility to obesity and metabolic diseases. BALB/c mice are known to be resistant to high fat diet (HFD)-induced obesity, however the genetic cause remains unknown. We report that deletion of the innate
Externí odkaz:
https://doaj.org/article/c00e8f898783402ab063d1e8e5fbaf3f
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146162 (2016)
Dysbiosis is a hallmark of inflammatory bowel disease (IBD), but it is unclear which specific intestinal bacteria predispose to and which protect from IBD and how they are regulated. Peptidoglycan recognition proteins (Pglyrps) are antibacterial, par
Externí odkaz:
https://doaj.org/article/7bbc10250e08452d8388d6ef3d6bb9e3
Publikováno v:
Trends in Molecular Medicine. 26:670-682
Peptidoglycan (PGN) is a cell wall component of both Gram-positive and Gram-negative bacteria. Signature fragments of PGN are proinflammatory through engagement of pattern recognition receptors (PRR) on resident tissue cells and circulating leukocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7eeb93a4be14aa29165321e3383d84
https://doi.org/10.1016/j.molmed.2019.11.006
https://doi.org/10.1016/j.molmed.2019.11.006
Autor:
Maria D. Juarez-Rodriguez, Iztok Hozo, Dipika Gupta, Ashley A. Detzner, Sunil Banskar, Roman Dziarski
Publikováno v:
The Journal of Immunology. 203:3113-3125
Changes in intestinal or respiratory microbiomes in infants correlate with increased incidence of asthma, but the causative role of microbiome in the susceptibility to asthma and the host genes that regulate these changes in microbiome are mostly unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5424a111f72fc6e1f5fcf282b8e0e1c
https://doi.org/10.4049/jimmunol.1900711
https://doi.org/10.4049/jimmunol.1900711
Autor:
Des Raj Kashyap, Annemarie Rompca, Ahmed Gaballa, John D Helmann, Jefferson Chan, Christopher J Chang, Iztok Hozo, Dipika Gupta, Roman Dziarski
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004280 (2014)
Mammalian Peptidoglycan Recognition Proteins (PGRPs) are a family of evolutionary conserved bactericidal innate immunity proteins, but the mechanism through which they kill bacteria is unclear. We previously proposed that PGRPs are bactericidal due t
Externí odkaz:
https://doaj.org/article/72570084344341a08d5a9d453b5e5f5c
Autor:
Roman Dziarski
'[A] worthy tribute to the extraordinary bravery of a remarkable woman.” — Publishers WeeklyIn World War II's Poland, thirty year old Zofia Sterner and her husband Wacek refuse to be classified as Jews destined for extermination.Instead, they
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67393 (2013)
Inflammatory bowel disease (IBD) is a common disease, includes Crohn's disease (CD) and ulcerative colitis (UC), and is determined by altered gut bacterial populations and aberrant host immune response. Peptidoglycan recognition proteins (PGLYRP) are
Externí odkaz:
https://doaj.org/article/2c1ef4959664456e896551c2114995b0