Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Roman, Akasov"'
Autor:
Tatiana Pallaeva, Alexander Mikheev, Daniil Eurov, Dmitry Kurdyukov, Victoriya Popova, Elena Dmitrienko, Roman Akasov, Daria Trushina
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 87 (2022)
A series of calcium carbonate particles with sizes of 500 ± 80 and 200 ± 90 nm were obtained using mass crystallization in aqueous salt solutions by varying the reaction conditions and adding glycerol or a combination of polyethylene glycol, polyso
Externí odkaz:
https://doaj.org/article/3d06e04cb1dc4d79a1a238fbf67420ab
Autor:
Oxana Ryabaya, Anastasia Prokofieva, Roman Akasov, Dmitry Khochenkov, Marina Emelyanova, Sergey Burov, Elena Markvicheva, Andrey Inshakov, Evgenia Stepanova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 2548-2560 (2019)
Melanoma is one of the most aggressive and treatment-resistant tumors that responsible for majority of skin-cancer related deaths. Here we propose a combination of MEK inhibitor binimetinib with metformin as a promising therapy against human melanoma
Externí odkaz:
https://doaj.org/article/4ebfc783ae0642faa8025d690c37fd99
Autor:
Roman Akasov, Maria Drozdova, Daria Zaytseva-Zotova, Maria Leko, Pavel Chelushkin, Annie Marc, Isabelle Chevalot, Sergey Burov, Natalia Klyachko, Thierry Vandamme, Elena Markvicheva
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 7, Iss 4, Pp 593-601 (2017)
Purpose: Multidrug resistance (MDR) of tumors to chemotherapeutics often leads to failure of cancer treatment. The aim of the study was to prepare novel MDR-overcoming chemotherapeutics based on doxorubicin (DOX) derivatives and to evaluate their eff
Externí odkaz:
https://doaj.org/article/705053c8e34c4bd49f38e564ed7f4eb6
Autor:
Mohamed F. Attia, Roman Akasov, Nancy M. Elbaz, Tyler C. Owens, Evan C. Curtis, Soham Panda, Ralph Santos-Oliveira, Frank Alexis, Forrest M. Kievit, Daniel C. Whitehead
Publikováno v:
ACS Applied Materials & Interfaces. 14:54389-54400
Here, we report the synthesis of robust hybrid iodinated silica-lipid nanoemulsions (HSLNEs) for use as a contrast agent for ultrasound and X-ray applications. We engineered iodinated silica nanoparticles (SNPs), lipid nanoemulsions, and a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe68f01757f6f70e8c8450837482c56
https://doi.org/10.1021/acsami.2c09104
https://doi.org/10.1021/acsami.2c09104
Publikováno v:
World Congress on Recent Advances in Nanotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb76f3065f8fad4ace7f7a10ee174e03
https://doi.org/10.11159/nddte23.129
https://doi.org/10.11159/nddte23.129
Autor:
Anastasia V. Sochilina, Vitaly P. Zubov, Evgeny V. Khaydukov, Roman Akasov, Alla N. Generalova, A. G. Savelyev
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:828-836
Abstract Materials based on hyaluronic acid (HA) are extensively used in tissue engineering as scaffolds. Photoinduced crosslinking is one way to prepare them, and, for this, HA must be modified with vinyl groups, which are capable of participating i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ebe9ed75090b088152ed9c53eace7a7
https://doi.org/10.1134/s1068162021040191
https://doi.org/10.1134/s1068162021040191
Autor:
Roman Akasov, Anastasia Prokofieva, I. S. Abramov, Nataly V Sholina, Oxana Ryabaya, D. A. Khochenkov
Publikováno v:
Investigational New Drugs. 39:987-1000
Objective The problem of drug resistance to BRAF-targeted therapy often occurs in melanoma treatment. Activation of PI3K/AKT/mTOR signaling pathway is one of the mechanisms of acquired resistance and a potential target for treatment. In the current r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235cee28673d8908a2e60cd568ad709d
https://doi.org/10.1007/s10637-021-01089-3
https://doi.org/10.1007/s10637-021-01089-3
Autor:
Deev Sm, Polina A. Demina, D. A. Khochenkov, Evgeny V. Khaydukov, A. V. Nechaev, N. V. Sholina, Roman Akasov, Alla N. Generalova, Irina V. Balalaeva
Publikováno v:
Doklady. Biochemistry and Biophysics
Abstract Upconversion nanoparticles (UCNPs) are a promising nanoplatform for bioreagent formation for in vivo imaging, which emit UV and blue light under the action of near-infrared radiation, providing deep tissue penetration and maintaining a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f817ffeb7e6a66b6282969a01b0ebd2
https://doi.org/10.1134/s1607672921020034
https://doi.org/10.1134/s1607672921020034
Autor:
Nikolay V. Zyk, Ksenia Yu Vlasova, Alexander L. Trigub, Olga O. Krasnovskaya, A. S. Semkina, Alexander G. Majouga, Dmitry A. Skvortsov, Elena K. Beloglazkina, Peter Gorelkin, Roman Akasov, Daniil Spector, Alexander Erofeev
Publikováno v:
Dalton Transactions. 50:7922-7927
In a recent research paper Dr. Suxing Jin et al. reported two multispecific PtIV complexes DNP and NP with non-steroidal anti-inflammatory drug naproxen (NPX) as the axial ligand(s). Herein, we clarify the mechanism of action of DNP, its therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d258d03815ebf9f1d534dba58d38c74d
https://doi.org/10.1039/d1dt00898f
https://doi.org/10.1039/d1dt00898f
Publikováno v:
ACS Biomaterials Science & Engineering. 6:6671-6679
We developed four types of para-phenylene-bridged periodic mesoporous organosilica NPs (p-P PMO NPs) with tailored physical parameters including size, morphology, porosity, and surface area using a new polymer-scaffolding approach. The particles have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fc6243a140ec8ec127280a0fa7493d
https://doi.org/10.1021/acsbiomaterials.0c01082
https://doi.org/10.1021/acsbiomaterials.0c01082