Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Romain Zufferey"'
Autor:
Fiona E. O’Keeffe, Romain Zufferey, Pam Tyers, Gerard W. O'Keeffe, Sarah A. Scott, Jeffrey W. Dalley, Maeve A. Caldwell
Neural stem cells (NSCs) are widely endorsed as a cell source for replacement strategies in neurodegenerative disease. However, their usefulness is currently limited by the inability to induce specific neurotransmitter phenotypes in these cells. In o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af84ac89be85f8437a2aa664990ea74
http://doc.rero.ch/record/291324/files/awm340.pdf
http://doc.rero.ch/record/291324/files/awm340.pdf
Autor:
Romain Zufferey, Stéphane Karlen
Publikováno v:
Applied Biosafety. 12:93-99
Autor:
Didier Trono, H Ye, Linh Pham, Romain Zufferey, Kah Whye Peng, Stephen J. Russell, François-Loïc Cosset
Publikováno v:
Gene Therapy. 8:1456-1463
Lentiviral vectors represent an attractive technology platform from which to develop a targetable injectable gene delivery system for transduction of specific cell populations in vivo, irrespective of their cell cycle status. Targeted HIV-1-based len
Autor:
Stefan Karlsson, Didier Trono, Niels-Bjarne Woods, Cecilia Fahlman, Isao Hamaguchi, Hanna K. A. Mikkola, Romain Zufferey, Sten Eirik W. Jacobsen, Karin Olsson
Publikováno v:
Blood. 96:3725-3733
The ability of lentiviral vectors to transfer genes into human hematopoietic stem cells was studied, using a human immunodeficiency virus 1 (HIV-1)-derived vector expressing the green fluorescence protein (GFP) downstream of the phosphoglycerate kina
Autor:
Didier Trono, Patrick Aebischer, Jack L. Tseng, L. Pereira de Almeida, Nicole Déglon, Anne D. Zurn, Yvan Arsenijevic, Jean-Charles Bensadoun, Romain Zufferey
Publikováno v:
Human Gene Therapy. 11:179-190
Glial cell line-derived neurotrophic factor (GDNF) is able to protect dopaminergic neurons against various insults and constitutes therefore a promising candidate for the treatment of Parkinson's disease. Lentiviral vectors that infect quiescent neur
Transgene Expression in the Guinea Pig Cochlea Mediated by a Lentivirus-Derived Gene Transfer Vector
Autor:
Robert M. Pettis, Wei Qiang Gao, Jay J. Han, Michael Wareing, Anil K. Lalwani, Anand N. Mhatre, Didier Trono, Romain Zufferey
Publikováno v:
Human Gene Therapy. 10:1867-1873
The utility of lentivirus as a gene delivery vector in the cochlea was evaluated in vitro and in vivo. Lentivirus transduction was assessed through expression analysis of a reporter gene, green fluorescent protein (GFP), integrated within the viral g
Publikováno v:
Journal of Virology. 73:2886-2892
The expression of genes delivered by retroviral vectors is often inefficient, a potential obstacle for their widespread use in human gene therapy. Here, we explored the possibility that the posttranscriptional regulatory element of woodchuck hepatiti
Publikováno v:
The EMBO Journal. 16:1164-1172
The central reaction in the process of N-linked protein glycosylation in eukaryotic cells, the transfer of the oligosaccharide Glc(3)Man(9)GlcNAc(2) from the lipid dolicholpyrophosphate to selected asparagine residues, is catalyzed by the oligosaccha
Autor:
Pedro Muniesa, Pedro Luis Herrera, Lelio Orci, Bernadette Mermillod, Francesca Sanvito, Jacques Philippe, Jean-Dominique Vassalli, Joaquin Huarte, Romain Zufferey, Anthony Nichols
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 91, No 26 (1994) pp. 12999-13003
Ontogenic relationships between the different types of endocrine cells in the islets of Langerhans were explored by generating transgenic mouse embryos in which cells transcribing the glucagon, insulin, or pancreatic polypeptide genes were destroyed
Autor:
Romain Zufferey, Jolanta Szulc, Allison D. Ebert, Bernard L. Schneider, Patrick Aebischer, Corey R. Seehus, Elizabeth E. Capowski, Clive N. Svendsen
Publikováno v:
Journal of neuroscience methods. 163(2)
Human neural progenitor cells (hNPC) hold great potential as an ex vivo system for delivery of therapeutic proteins to the central nervous system. When cultured as aggregates, termed neurospheres, hNPC are capable of significant in vitro expansion. I